Naším hlavním příspěvkem je, že terapie s trvalým uvolňováním integruje výhody chemoterapie a imunoterapie a poprvé byly oba kombinovány a aplikovány na intratumorální terapii prostřednictvím zásahu. It integrates local and global treatment, and increases the concentration and time of drug action through sustained release of drugs within the tumor, which not only plays a local anticancer effect of chemotherapy drugs, but also takes into account the role of systemic immunotherapy, thus making up for the shortcomings of other therapies, providing new ideas and approaches for cancer treatment, especially for middle and advanced tumors, especially for reducing tumor recurrence and inhibiting tumor The transfer has very important hodnota; UMPIC terapie má výhodu použití nádoru jako zdroje antigenu a autologní vakcíny, která je také v souladu s vývojovým trendem personalizované medicíny. And applied to the clinic, hapten combined with chemotherapy drugs for sustained release treatment of pancreatic cancer primary focus, while inducing distal effect, the essence of which is to induce immune response, T-cell-related CD4, CD8, DC, T and NK cells, and B-cell-related tumor autoantibodies: Antibodies to P53, P16, Cmyc, Zeta, IMP1, Koc, Survivin, p62, HCC1 and other oncogenes, this is the first time to find that T and B are involved in the immune response, and the clinical functions of the distal effect and this therapy was selected for "Clinical Operation Guidelines for Interventional Treatment of Advanced Pancreatic Cancer" (Trial) (7th edition) jointly formulated by the Chinese Anti-Cancer Association, the National Clinical Medical Research Center for Radiology and Therapy, and the National Intervention Medicine Innovation Alliance byla publikována v Journal of Clinical Radiology, Svazek 43, číslo 19, 2024, 1636-1648.