Sabon rashin ilimin sel na ciwon jini

Rashin karancin sel mai karfin sel (NSCLC) shine jagorar yiwuwar azaba ta ciwon daji a duk duniya. Abin farin ciki, ingantaccen ci gaba a cikin zaɓuɓɓukan magani suna fitowa, yana ba da sabon bege don inganta sakamako da ingancin rayuwa. Wannan labarin yana bincika sababbin Sabon rashin ilimin sel na ciwon jini, gamsarwa da kwastomomin da aka yi niyya, immunotherreapes, imnotherapys, da kuma rashin fahimtar ciwon kan sel seader hung. Ya mamaye yawancin substetpes, gami da Adenocarcinoma, selemous tantanin halitta, da kuma babban carcinoma sel. Mataki na NSCLC a ganewar asali yana tasiri ga zaɓukan magani da hangen nesa. Za'a iya kula da farkon-carie tare da tiyata, yayin da yake ci gaba da yawa matakan yawanci suna kaiwa wasu sunadarai ko kwayoyin halittar da suka haifar da ci gaban tantanin halitta da kuma rayuwa. Wadannan hanyoyin kwantar da hankali suna da tasiri kuma suna da ƙarancin sakamako fiye da maganin maganin gargajiya. Maƙasudin yau da kullun a cikin NSCLC sun haɗa da EGFr, Alk, Ros1, Braf, da Motfita Ci gaban Cikakken Wasu ciwace-ciwacen dabbobi na NSCLC suna da maye gurbi a cikin ƙwayar EGFR, yana haifar da haɓakar ƙwayar ƙwayar cuta. Egfr masu hana, kamar gefitib, Erlotiniib, Afatanib, toperrtitib, ya toshe ayyukan Egfr, yana raguwa.Fa'idodi: Sau da yawa tasiri a cikin marasa lafiya tare da cutar egfr, yana haifar da ingantacciyar rayuwa da ingancin rayuwa.Tasirin sakamako: Fata na fata, zawo, fatigie.oSimertinib shine mafi yawan lafazin na farko don ƙwayoyin cuta na egfr-mutated ne idan aka kwatanta da na ƙarfafawa na ƙarni na farko. Kuna iya ƙarin ƙarin koyo game da masu hana cutar daga Gidan yanar gizon cutar kansa na Amurka.Kahibitorsanna Lymphomaplastic Lymphoma Kinase (Alk) wani furotin ne wanda za'a iya maye gurbinsa da NSCLC. ALK masu kame, kamar Crizotinib, CerieTinib, Brigatinib, da Lorlatinib, suna bin diddigin furotin.Fa'idodi: Inganci a cikin marasa lafiya tare da Alk kayan aiki, wanda ya haifar da ingantaccen rayuwa da rage cutar ci gaba.Tasirin sakamako: Tunaninsa yana canzawa, tashin zuciya, amai, gudawa. Ciwon daji Bincike UK Yana ba da ƙarin bayani.Ros1 Inhibitorsros1 shine mai karɓuwa Tyrosine cewa, lokacin da aka harba da wani gene, zai iya fitar da ciwon daji. ROS1 masu hana, kamar crizotinib da entoltib, ana amfani dasu don magance NSCLC tare da Ros1 Fusions.Fa'idodi: Muhimmin ciwan ruwa da tsawan tsinkaye a cikin marasa lafiya tare da ROS1-tabbatacce NSCLC.Tasirin sakamako: Kamanni da alka na nuna alkawarin wa'adi saboda iyawarsa don ya haye sharri-kwakwalwa mai jini, yana ba shi tasiri don kula da mettiase kwakwalwa. Duba Shafin yanar gizo na Turai Don cikakken bayani.im nukukuka ga gargajiya na nscl nothaneshin ikon cutar da jikin mutum don yakar cutar kansa. Abubuwan da ke hana su na rigakafi akwai nau'in rigakafin rigakafi wanda ke hana tsarin rigakafi da aka gabatar daga ƙwayoyin cutar kansa (PD-1) da kuma shirye-shiryen cutar sel na cutar kansa-1 (PD-1) kuma suna taimakawa sel sel na musger a kansu tsarin rigakafi. Pd-1 / PD-L1 masu hana, kamar kwarangwal, da Atezolumab, da Durvalumab, toshe wadannan sunadarai, suna ba da wadannan sunadarai don gane da sel na cutar kansa.Fa'idodi: Ambadan martani da Ingantattun rayuwa a cikin subsarfin marasa lafiya tare da Nsclc.Tasirin sakamako: Abubuwan da ke da alaƙa da ke da alaƙa da su, kamar yadda ƙwayar ƙwayar cuta, colitis, da hepatitis ana amfani da shi azaman jiyya na farko don mahaɗan na NSCLC tare da magana ta PD-L1. Ana iya samun ƙarin bayani akan Yanar gizo FDA.Tla-4 inhibitorscytoxic t-hymphococyte-hadarancin furotins 4 (CTLA-4) wani furotin ne wanda zai iya murkushe tsarin rigakafi. IPlailmallab ne CTla-4 inhibitor wanda za'a iya amfani dashi a hade tare da PD-1 masu hana su inganta amsar rigakafi game da sel na ciwon daji.Fa'idodi: Na iya inganta rayuwa idan aka hade da masu hana ruwa 1.Tasirin sakamako: Yawancin muhimman sakamako masu amfani da kwastomomi idan aka kwatanta da PD-1 masu hana su sauya aikin NSCLC, Chemotherapy ya kasance wani zaɓi mai mahimmanci, musamman a hade tare da sauran jiyya. Sabon rashin ilimin sel na ciwon jini galibi suna hada da hada cutar kimantawa tare da rigakafin hana daukar ciki don inganta tasiri.chemooim nayi amfani da sakamako masu cutar sankarau da aka nuna Sabon rashin ilimin sel na ciwon jini. Wannan ƙirar na ƙirar ƙwararrun iyawar ƙwaƙwalwar ajiya don lalata ƙwayoyin cutar sankarar mahaifa da kuma saki antigens, sa su zama mai saukin kamuwa da su. Ausan Imwaothera na iya amsar amsar rigakafi, yana haifar da haɓaka sakamako.Fa'idodi: Ingancin rayuwa da kuma yawan da amsa aka kwatanta da Chemothera shi kadai.Tasirin sakamako: Extraarin haɗarin duka masu ilimin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa. Wannan hanyar tana iya taimakawa shawo kan hanyoyin yin rikici da kuma inganta sakamakon magani.Fa'idodi: Na iya mayar da hankali ga magani da inganta rayuwa.Tasirin sakamako: Haramarin haɗarin sakamako masu tasirin sakamako daga duka magunguna Sabon rashin ilimin sel na ciwon jini da dabaru. Kasancewa cikin shari'ar asibiti na iya samar da damar yin amfani da kwayar halittar-baki waɗanda ba su da yawa. Cibiyar Bincike ta Shandong Cibleer Cener Citizenaliyar ta himmatu wajen fafatawa da binciken cutar kansa kuma yana ba da sabis wajen yin shari'ar a asibiti da ba a samun su ba tukuna. Moreara koyo game da gwajin asibiti a Shandong Cibiyar Bincike Centie.Emerging masu koyar da hankali a cikin asibiti na asibiti Sabon rashin ilimin sel na ciwon jini a halin yanzu ana kimanta su a cikin gwaje-gwajen asibiti, gami da:Magungunan rigakafi-Magunguna Conjugate (AdCs): Wadannan kwayoyi sun ba da maganin chemotherapy kai tsaye a cikin sel na cutar kansu, rage girman lalacewar sel.Anticific Wadannan maganin rigakafi suna ɗaure ƙwayoyin cutar kansa da sel na rigakafi, suna kawo su don haɓaka amsar rigakafi.ARAPERARINLUES (E.G., Ciki-T Cely Terrapy): Waɗannan maganiniyoyin rigakafi sun ƙunshi canza sel na rigakafi da lalata da sel na ciwon daji. Yi la'akari da binciken albarkatu daga ƙungiyoyi kamar Kungiyar Hadin Kan Amurka ko Gidauniyar Lunnevity.Discimer: Wannan labarin shine don dalilai na bayanai kawai kuma bai kamata a dauki shawarar lafiya ba. Da fatan za a nemi shawara tare da mai ba da lafiyar ku don shawarwarin na keɓaɓɓen shawara.