Tsis yog cov kev kho mob me me cancer cancer cancer

Tsis yog-me me cell mob cancer (NSCLC) yog ib hom mob ntsws uas mob ntsws. Cov kev kho mob rau NSCLC tau sib txawv thiab nyob ntawm ntau yam, nrog rau theem ntawm kev noj qab haus huv, thiab kev sib raug zoo ntawm cov qog. Daim ntawv qhia no muab cov ntsiab lus ntawm kev kho mob loj rau kev phais thiab tshuaj tua kab mob, txhawb nqa cov kev paub ntawm kev txiav txim siab.Tsis yog-me me cell mob cancer (NSCLC) yog ib pab pawg ntawm cov qog nqaij hlav uas coj cwj pwm zoo sib xws. Cov ntsiab ntawm NSCLC suav nrog Adenocarcinoma, squamous cell carcinoma, thiab cov carcinomy loj heev. Kev kuaj mob yog lawm, suav nrog kev xeem thiab molecular, yog qhov tseem ceeb rau kev txiav txim siab cov tswv yim zoo tshaj plaws. Shanga Cancer Kev Tshawb Fawb Lub Koom Haum tau mob siab rau cov kev tshawb fawb cancer thiab kev txhim kho kev kho mob tshiab, kawm paub ntau ntxiv ntawm https://baofahospital.com.Txawm ntawm NSCLCNSCLC yog staged siv TNM system (qog, ntawm, Metastasis). Cov theem piav txog qhov loj me thiab qhov chaw nyob ntawm thawj cov qog (t), seb tus mob cancer kis ze rau cov chaw (M). Theem kev khwv ntau ntawm kuv (pib theem) rau iv (qib theem siab) .molcolecular qhia txog cov noob sib txawv lossis cov protein txawv txawv nyob rau hauv cov qog hlwb. Cov biomarers no pab txiav txim siab tias tus neeg mob yog ib tus neeg sib tw rau kev kho mob rau kev kho mob. Cov kev sib hloov xws li EGF, Alk, Ros1, Braf, thiab lwm tus. Cov txiaj ntsig ntawm cov molecular kuaj cov kev cuam tshuam ntau dua kev txiav txim siab kho tswv yim.Ceb NSCLC kev kho mobKev phais mob feem ntau yog kev kho thawj-kab rau cov theem thaum ntxov-theem I thiab II). Lub hom phiaj yog kom tshem cov qog thiab cov qog ntshav ze. Hom kev phais xws li: NPOG REWECTION: Tshem tawm ntawm ib qho me me, npoo-puab daim ntawm lub ntsws. Segmentectomy: Kev tshem tawm ntawm qhov loj dua ntawm lub ntsws ntau dua li kev rov pib dua. Lobectomy: Tshem tawm ntawm tag nrho Lobe ntawm lub ntsws. Qhov no yog cov txheej txheem phais feem ntau rau NSCLC. Pneumonectomy: Tshem tawm ntawm tag nrho lub ntsws. Qhov no tsis tshua muaj ntau thiab tshwj tseg rau ntau cov qog txav dav hlau.Voo siv hluav taws xob ntau rau kev tua cov kabmob kheesxaws. Nws tuaj yeem siv los ua kev kho mob tseem ceeb, tom qab kev phais mob los tua ib qho kev mob hlwb, lossis daws cov tsos mob hluav taws xob (palliative). Ntau hom hluav taws xob kev kho xws li: Sab nraud nqaj hluav taws xob hluav taws xob (EBRT): Hluav taws xob yog xa los ntawm lub tshuab sab nraud lub cev. Stereotactic lub cev hluav taws xob hluav taws xob (SBRT): Xa cov koob tshuaj ntau ntawm hluav taws xob mus rau thaj chaw me me, muaj cov khoom. Feem ntau siv rau thaum ntxov-theem NSCLC thaum kev phais mob tsis yog kev xaiv. Brachythertherapy (sab hauv hluav taws xob kev kho mob): Cov khoom siv hluav taws xob muab tso ncaj qha sab hauv cov qog lossis ze nws.chemotherapital siv tshuaj los tua cov qog nqaij hlav cancer thoob plaws lub cev. Nws feem ntau siv hauv kev phais mob lossis kev kho hluav taws xob, lossis ua ib qho kev kho mob tseem ceeb rau kev tshaj lij NSCLCCov. Cov Khoom Siv Kev Siv Kev Puas Tsuaj Rau NSCLC suav nrog Cisclatin, Carboplatin, paclitaxel, Docetexel, thiab Gemcitabine.Target Thoj Kev Kho Mob Rau NSCLC kev kho mobKev kho mob yog tshuaj uas lub hom phiaj tshwj xeeb molecules koom nrog Cancer Kev Loj Hlob thiab Ciaj sia taus. Cov kev kho mob no tsuas yog ua tau yog tias cov qog muaj kev sib hloov lossis protein tshwj xeeb.KF Intibitiongfr (epidermal kev loj hlob receptor (inhibitors tau siv los kho NSCLC nrog EGFr hloov zuj zus. Cov tshuaj thaiv no cov tshuaj kabmob EGFR protein, uas pab kheescawv cov qog nqaij hlav. Cov piv txwv muaj xws li: GreaSa) Eressa) Erlotinib (Taratrif) Oscitorsalalk (anegrasto lymboma Kinase) Inhibitors yog siv los kho NSCLC nrog alk cov gene rearrangies. Cov tshuaj thaiv cov alk protein, uas pab kheesxaws cov qog nqaij hlav cancer loj hlob. Piv txwv li: Crizotinib (Xalrinib) Ceritinib (Alecensa) Lorlatinib (Lorlrena) Ros1 InhibitorsRos1 Inhibitors tau siv los kho NSCLC Nrog Ros1 cov gene rov qab. Cov tshuaj thaiv cov Ros1 protein, uas pab kheescawv cancer loj tuaj. Piv txwv li: Crizotinib (Xalori) Entrectinib (ROAZLYTREK) Braf Inibitorsebraf Inhibitors yog siv los kho NSCLC nrog Braf V600E sib hloov. Cov tshuaj no thaiv cov neeg muaj protein braf. Piv txwv li: Dabrafenib (TABRARIBLAR) trametinib (siv ua ke nrog Dabrafenib) (siv rau hauv kev kho mob DabraTib) (siv rau cov kev kho mob Piv txwv suav nrog kev so kom rov qab ua cov fusions) thiab ua kom muaj inhibitors (rau kev ntsib exon 14 Skis Mav) .immunotherapy rau NSCLC kev kho mobKev txhaj tshuaj tiv thaiv kev txhaj tshuaj pab lub cev tiv thaiv mob cancer. Lawv ua haujlwm los ntawm kev thaiv cov protein uas tiv thaiv kev tiv thaiv kab mob tiv thaiv kab mob los ntawm kev tawm tsam cov kabmob hlwb. Cov no yog nquag siv nyob rau hauv NSCLC Kev Kho Mob.PD-1 / PD-L1 inibitorspd-1 (PD-Ligand 1) thiab PD-Ligham 1) Thiab pab las-Ligwor 1) Piv txwv li: Pembrolizumab (Keystruda) Nivolumo) Flimchodab (IMTOTHOLOGCE) Protein, uas tseem yuav pab tau cov cancer cancer nkaum txoj kev tiv thaiv kab mob. Ib qho piv txwv yog Ipilualeab (yervoy), feem ntau siv hauv kev sib xyaw nrog PD-1 inhibitors.comBining Herapiesoften, NSCLC kev kho mob koom nrog kev sib xyaw ntawm cov kev kho mob sib txawv. Piv txwv, kev phais mob tuaj yeem ua raws li los ntawm kev siv tshuaj kho mob lossis hluav taws xob kho. Lub hom phiaj kev kho mob lossis tshuaj tiv thaiv kab mob yuav ua ke nrog kev siv tshuaj kho mob. Cov kev sib xyaw ua ke yuav yog nyob ntawm tus neeg mob qhov xwm txheej. Txhawm rau nrhiav kom paub ntau ntxiv txog kev tshawb fawb cancer Shanga Cancer Tshawb Fawb Txog Lub Koom Haum.Clinical kev sim siab yog cov kev kawm tshawb fawb uas ntsuas kev kho tshiab lossis kev sib xyaw ua ke. Cov Neeg Mob NSCLC Tej zaum yuav txiav txim siab koom nrog hauv kev sim tshuaj xyuas kom nkag mus rau cov kev kho mob txiav. Cov ntaub ntawv hais txog cov kev sim hauv tsev kho mob tuaj yeem nrhiav tau ntawm National Cancer Instantage lub vev xaib thiab lwm cov npe tseem ceeb.side cov txiaj ntsig NSCLC kev kho mob tuaj yeem ua rau phiv. Nws yog ib qho tseem ceeb los tham txog cov kev mob tshwm sim nrog koj tus kws kho mob thiab kawm paub tswj hwm lawv li cas. Kev saib xyuas kev saib xyuas, xws li kev tswj hwm qhov mob thiab kev txhawb nqa kev noj haus zoo, tuaj yeem pab txhim kho lub neej zoo thaum lub sij hawm kho.pogcosos thiab rov qab mus kuaj rau NSCLC Nyob ntawm theem ntawm tus mob cancer, tus neeg mob ua haujlwm tag nrho, thiab cov mob cancer tau kho kho mob. Cov kev teem caij rov qab ua raws li cov kev teem caij ib ntus los saib xyuas kom rov muaj dua thiab tswj cov kev mob tshwm sim ntev ntawm kev kho.DISCLAIMER: Kab lus no muab cov ntaub ntawv dav dav txog Tsis yog-me me cancer mob cancer cancer me me (NSCLC) thiab yuav tsum tsis txhob txiav txim siab kho cov lus qhia kev kho mob. Ib txwm sab laj nrog koj tus kws kho mob lossis lwm tus kws kho mob rau tus kheej cov lus pom zoo hais txog koj tus mob tshwj xeeb.