kuvura ibihaha bya kanseri ya kanseri

Kuvura ihinduka ry'igihugu mu buryo bw'ibihaha no kuvura ibihatsi by'ibihaha no kuvura kanseri y'ibihaha: Kanseri Yuzuye Amabwiriza nindwara igoye, kandi ubuvuzi bwayo akenshi biterwa na mutation yihariye ihinduka mu bibyimba. Aka gatabo gatanga incamake yuzuye y'uruhare rwo kwipimisha genetike muri kanseri y'ibihaha, mu ihinda, no guhitamo ihari. Igamije guha imbaraga abarwayi nimiryango yabo bifite ubumenyi bukenewe kugirango bayobore uru rugendo rutoroshye. Tuzasesengura amashanyarazi, Imbimubyo, hamwe nizindi ngamba zikoreshwa muri ubu mugucunga kanseri y'ibihaha biterwa na genetike idasanzwe.

Ikizamini cya genetike muri kanseri y'ibihaha

Akamaro ko kuranga molekile

Mbere yo gutangira kuvura ibihaha bya kanseri ya kanseri, kugerageza genetitike ni ngombwa. Iyi nzira, ikunze kuvugwa nkibisobanuro bya molecular cyangwa ibinyabuzima, byerekana guhinduranya geneti kuri selile yibibyimba. Ihindura rishobora guhindura ibyemezo byo kuvura no guhanura amahirwe yo kuvura. Genovile zisanzwe zirimo EGFR, ALK, ROS1, Craf, na Kras. Kumenya umuyoboro wihariye ushingiye kuri decologue yemerera ababike umuhanga mu buvuzi bwa kanseri yumurwayi kugiti cye. Ibisubizo by'ibizamini bya genetike ni ngombwa mu kugena inzira nziza y'ibikorwa.

Ubwoko bwibizamini bya genetike

Uburyo bwinshi burahari kubizamini bya genetique, buri kimwe hamwe nibyiza byacyo nibibi. Ibi birimo gukurikiranya-igisekuru gikurikira (Ngs), bituma bigera kuri kanseri nyinshi, na Polymeyese reaction (PCR), uburyo bugamije kwibanda kuri gen. Guhitamo uburyo biterwa nibintu nkubikoresho bihari nibibazo byihariye bya kavukire bivugwa. Oncologue yawe azakuyobora muburyo bwiza bwo kwipimisha ukurikije ikibazo cyawe.

Ibisanzwe bisanzwe muri kanseri y'ibihaha no kuvura kwabo

Egfr ihinduka

Ubu egfr ihinduka risanzwe muri kanseri idafite kanseri nto (NSCLC), cyane cyane kubarwayi batigeze banywa itabi cyangwa bafite amateka yoroheje itabi. Ubuvuzi bwibanze, nka egrosine tyrosine kinase (TKIS), nibyiza cyane kubarwayi bafite ihinduka ryibihinduka. Aba bagizi babuza bahagarika ibikorwa bya poroteyine evfr poroteyine, kubangamira kwigirirwa. Ingero zirimo Gefitinib, Erlotinib, na Afatinib. Ariko, kurwanya iyi miti birashobora gutera imbere mugihe runaka.

ALK Rearngengements

Alk Imyitozo ngororangingo niyindi mukunzi wingenzi cyane muri NSCLC. Bisa na Egfr Mutations, ALK Rearungeoments ikunze kwibasirwa na TKIs yihariye. CRYTINIB na Aptinib ni ingero za Alk Abayahudi bagaragaje neza mu kuvura abarwayi hamwe na kanseri y'ibihaha alk-nziza. Gukurikirana buri gihe ni ngombwa kumenya no gucunga imyigaragambyo iyo ari yo yose ishobora gutera imbere.

ROS1 Imyidagaduro

ROS1 Imyidagaduro ntihara kenshi kuruta egfr cyangwa alk rearungenoments, ariko basangiye uburyo bwo kuvura. Abarwayi bafite kanseri y'ibihaha byiza barashobora kungukirwa no kuvuza intego, nka crizotine, lorlatinib, na entretinib. Izi mvugo zerekanye intsinzi mukurokoka kubaho no kuzamura imibereho kubarwayi bafite iyi gahunda.

IZINDI MUHITAMO

Ibindi byinshi bitandukanye byamoko birashobora kugira uruhare mu iterambere rya kanseri y'ibihaha, harimo na BRAF, KRAs, na Mutation ya Het2. Mugihe abatisizi bahari kuri bimwe muribi bihinduka, ahantu havubirira bigenda bihinduka, hamwe nubushakashatsi bukomeje butusanya amahitamo mashya kandi anoze. Shandong Baofa Kanseri Ikigo cyubushakashatsi (https://www.baofahospasdatan.com/) iri ku isonga ryubu bushakashatsi, guhora dushakisha uburyo bushya kandi bushya bwo kuvura kanseri y'ibihaha.

Ingamba zo kuvura birenze kuvura

Impfuya

ImpubumeTherapy ikoresha imbaraga zumubiri wumuhanga mu kurwanya kanseri. Abashinyaguzi bagenzura, nka Pembezimab na Nivolumab, bakoreshwa muri kuvura ibihaha bya kanseri ya kanseri, rimwe na rimwe muguhuza na terapies zigamije cyangwa chimiotherapie. Iyi miti ihagarika kugenzura umudayimoni, yemerera sisitemu yumubiri kumenya neza no gutera kanseri. Impindurarapy irashobora kuba ingirakamaro no mubihe aho abafite amashanyarazi adashobora gukoreshwa.

Chimiotherapie

Chimitrapi ikomeje kuba uburyo bwo kuvura kuri kanseri y'ibihaha, cyane cyane mugihe aho abafite amashanyarazi cyangwa imyuka idakwiriye. Ariko, muri chimiotherapie mubisanzwe itabasiwe cyane kuruta amashanyarazi mashya, kandi irashobora kugira ingaruka zikomeye.

Imivugo

Umuvugizi w'imirasire urashobora gukoreshwa mu ntego no gusenya kanseri. Bikunze gukoreshwa muguhagarika ibibyimba, kugabanya ububabare, cyangwa kugabanya ibindi bimenyetso. Irashobora gukoreshwa wenyine cyangwa guhuza nubundi buryo.

Kuyobora Urugendo rwo kuvura

Ubwoko bwo kuvura	Ibyiza	Ibibi
IGITABO	Ibyingenzi mu murongo runaka, ingaruka nkeya kuruta chimiotherapie.	Kurwanya birashobora gutera imbere, bidafite akamaro kuri ihinduka ryabyo.
Impfuya	Ibisubizo biraramba, birashobora kuba byiza ndetse no kurwanya izindi mbuga.	Ubushobozi bwo kubikorwa bibi.
Chimiotherapie	Ingirakamaro muburyo bwinshi bwa kanseri, irahari cyane.	Ingaruka nyinshi zitari zo mu buvuzi cyangwa kudahindura imyuka, kudakunda.

Guhitamo uburenganzira kuvura ibihaha bya kanseri ya kanseri ni inzira igoye isaba ubufatanye bwa hafi hagati yumurwayi, oncologiste yabo, hamwe nabandi bahanga mu buvuzi. Ni ngombwa kubaza ibibazo, kumva uburyo bwo kuvura, no kugira uruhare rugaragara mu gufata ibyemezo. Wibuke, iterambere mubushakashatsi buringaniza ingamba za kanseri y'ibihaha. Stay informed, and don't hesitate to seek support from patient advocacy groups and support networks.Disclaimer: This information is for educational purposes only and should not be considered medical advice. Buri gihe ujye ubaza umunyamwuga wubuzima kubibazo byose byubuzima cyangwa mbere yo gufata ibyemezo bijyanye n'ubuzima bwawe cyangwa kuvura.