kuvura renal selile carcinoma patcinoma pathology ishyiraho ibitaro

Gusobanukirwa sirninoma remer: Urupapuro rwa Pathologiya & Gutunganya Ibitaro Guhitamo Carcinoma ya Renal Solx (RCC) bisaba uburyo bwinshi, guhuza indwara ya patologiya, amaradiyo. Iki kiganiro cyingenzi cya RCC, cyerekana ibintu byinshi byo gusuzuma, imikoreshereze, hamwe no kuvura biboneka mubitaro byumye.

Renal selile karcinoma: Incamake ya pathologiya

Renal selile karcinoma (kuvura renal selile carcinoma patcinoma pathology ishyiraho ibitaro) Nubwoko busanzwe bwa kanseri yimpyiko, bikomoka kuri epithelial ya tubule ya renal. Gusuzumwa neza kwibinya ningirakamaro mugutega inama yo kuvura no guhanura prognose. Ikizamini cyerekana icyerekezo gitandukanye, kigira ingaruka ku bugizi bwa nabi no kuvura. Ubucuruzi bwibanze burimo selile isobanutse RCC (CCRCC), Papillary RCC, Chromosophobe RCC, nabandi. Buri subtype yerekana ibintu bidasanzwe bya microscopique idasanzwe, bigira ingaruka kubikorwa no kuvura ingamba.

Gukuramo Akagari ka karutu wa karutu (CCRCC)

Konti ya CCRCC kuri benshi muri RCC. Pattologique, irangwa na cytoplasm isobanutse muri selile yibibyimba kubera glycogen nyinshi na lipide. Utugingo ngengabuzima dukunze kwerekana uburyo butandukanye bwo gukura, gukora ibyari cyangwa tubules. Kuba hari imyanya yihariye ya genetike, nka vhl gene ihinduka, bikunze kugaragara.

Papillary Renal Carcinoma

Papillary RCC itandukanijwe nuburyo bwo gukura kwa papirary, hamwe na selile zikora ibiryo cyangwa papillae. Bitandukanye na CCRCC, cytoplazme ntisobanutse neza. Subtypes ebyiri zibaho: Ubwoko bwa 1 nubwoko bwa 2, hamwe nubwoko bwa 2 bujyanye no kubabara nabi.

Chromosophobe renal carcinoma

Chromosophobe rcc ntabwo asanzwe kandi arangwa na selile hamwe na frale, inzoga za eosinophilic kandi ugereranije niclear. Akenshi ifite uburyo butandukanye bwo gukura, gukora ibyari cyangwa impapuro.

Izindi subtypes

Izindi mbaraga nyinshi zibaho, zirimo gukusanya umuyoboro wa CARCINO, mebullary RCC, na RCC. Iyi subtypes akenshi isaba ubuhanga bwihariye bwo gusuzuma no kuboneza urubyaro.

Gukoresha no Gutera imbere muri RCC

Strange Pathologiya, ishingiye kuri sisitemu ya TNM (Ingano yigifuniko, uruhare rwa Nodal, na Metastasis ya kure), nibyingenzi kugirango bimenye urugero rwindwara. Aya makuru, kuruhande rwihariye rwa RCC nizindi mpamvu zishimishije nkicyiciro (mbega ukuntu selile za kanseri zigaragara munsi ya microscope), zigira ingaruka zingamba zifata. Hejuru urwego, twongeye kuvura muri rusange.

Amahitamo yo kuvura kuri renal selile karcinoma

Guhitamo kwivuza biterwa nibintu bitandukanye, harimo icyiciro, amanota, nubuzima bwumurwayi muri rusange. Amahitamo avuye kubaga (Nephrecremy cyangwa Neprecremy), Ubuvuzi bwimiterere, Imyumuvumvumu, hamwe nubuvuzi bwimirasire.

Inkunga yo kubaga

Gukuraho kubaga bikunze kwivuza kwa mbere RCC. Abacuranga igice barinda ingirabuzimafatizo bafite ubuzima bwiza, mugihe abacurangabumbaranga bikubiyemo gukuramo impyiko zose ndetse na lymph node. Guhitamo biterwa nibintu byinshi, harimo ubunini n'ahantu h'ibibyimba, hamwe n'umurwayi muri rusange.

IGITABO

Abakozi bagenewe Tyrosine Kinase Ababuza (TKIS), byihariye proteins idasanzwe yo gukura kwa RCC. Iyi miti yahinduye imiti yateje imbere ya RCC yateye imbere, kunoza umubare urokoka. Ingero zirimo Suwitinib, Sorafenib, na Pazopanib.

Impfuya

Impunoray Harses sisitemu yumubiri wumubiri kurwanya selile za kanseri. Abagizi ba nabi, nka NIVOLUMAB na ipilimab, ni uburyo bwiza bwo kuvura RCC. Ibi biyobyabwenge bikora kurekura feri ku sisitemu yumubiri, kubikesha neza kumenya neza no gutera kanseri ya kanseri.

Imivugo

Umuvugizi w'imirasire urashobora gukoreshwa mubihe runaka, nko kwita kubitekerezo byindwara yateye imbere cyangwa dufatanye nubundi buryo.

Guhitamo ibitaro byiza bya RCC

Guhitamo ibitaro bikwiye kuri kuvura renal selile carcinoma patcinoma pathology ishyiraho ibitaro ni ngombwa. Shakisha inzego zifite amakipe menshi y'inararibonye harimo n'ababitabinyagu, abatecali, abahanga mu by'ishuri, n'abaganga n'ababitangaza kuri radiyondorono muri kanseri ya Genitourinary. Shandong Baofa Kanseri Ikigo cyubushakashatsi (https://www.baofahospasdatan.com/) Ese urugero rw'ibitaro byagejeje gutanga imiti yuzuye ya kanseri, hamwe n'abahanga mu kwisuzumisha no kuvura karcinoma ya renal. Reba ibintu nkigifite ubushobozi bwikoranabuhanga, uruhare rwubushakashatsi, hamwe na serivisi zunganira mugihe ufata icyemezo.

Umwanzuro

Gutsinda kuvura renal selile carcinoma patcinoma pathology ishyiraho ibitaro bisaba kwisuzumisha neza, harashizweho neza, hamwe na gahunda yo kuvura. Mugusobanukirwa imiterere ya RCC, subtypes zitandukanye, hamwe nuburyo bwo kuvura, abarwayi barashobora gufata ibyemezo byuzuye ku bufatanye nitsinda ryabo ryubuzima. Guhitamo kw'ibitaro ni ngombwa kubisubizo byiza bishoboka.