Kuvura Ibiyobyabwenge Gutanga Ibitaro bya kanseri

Iki gitabo cyuzuye gishakisha iterambere na porogaramu ya Kuvura ibiyobyabwenge murwego rwibitaro bya kanseri. Twiyeje muburyo butandukanye, inyungu, ibibazo, nibikorwa bizaza byuyu muriyi umurima wingenzi, gutanga ubushishozi bujyanye ninzobere mu byubuzima n'abashakashatsi. Amakuru yatanzwe ashingiye kubitabo byubumenyi nuburyo bwinganda.

Gusobanukirwa gutanga ibiyobyabwenge

Ni ibihe byatangajwe n'ibiyobyabwenge?

Kuvura ibiyobyabwenge Sisitemu yateguwe kugirango itange neza abakozi ba Tratheutic kugera kuri selile kavukire mugihe bagabanya ibyangiritse kumyenda myiza. Ubu buryo bugamije kuzamura imikorere, kugabanya ingaruka mbi, no kunoza ibizagurwa muri rusange ugereranije nuburyo bwa chemitherapi. Ingamba nyinshi zibaho kugirango zigerweho kuri iki gishushanyo, harimo no kurwanya ibiyobyabwenge, nanoparticles, na liposomes.

Uburyo bwo gukora

Ubu buryo busanzwe bukoresha kwibasira ligands, nka antibodies cyangwa inyenzi, ihambira cyane cyane kwakirana gukabije kwa kanseri. Bimaze guhambirwa, ibiyobyabwenge bimaze kurekurwa, biganisha ku kuvura bwaho kandi bigabana uburozi bwa sisitemu. Guhitamo uburyo bwo gutanga biterwa nibintu nkubwoko bwa kanseri, imitungo yibiyobyabwenge, hamwe ningaruka zifuzwa. Imikorere ya Kuvura Ibiyobyabwenge Gutanga Ibitaro bya kanseri yiyongereye cyane mubushakashatsi bukomeje.

Uburyo bwo gutanga ibiyobyabwenge

Antibody-ibiyobyabwenge (ADCs)

ADCS ihuza ibiyobyabwenge bya cytotoxique hamwe na antibody monoclonal yibasiye kanseri yihariye ya kanseri. Ubu buryo buremeza ko ibiyobyabwenge bigenwa mbere na selile za kanseri, bigabanya uburyo bwo kwerekana no kugabanya ingaruka mbi. Adcs nyinshi zemejwe gukoresha ivuriro kandi zikoreshwa mu buryo busanzwe muri protocole yo kuvura kanseri. Ingero zirimo trastuzumab emtine (kadcyla) na bretoximab vedotin (adcetris).

Nanoparticle-Gutanga

Nanoparticles, nka liposomes, na polymeric nanoparticles, na anorganic nanoparticles, birashobora gutsemba abakozi ba orapeutic no kuzamura imibare yabo kubibyibu. Ibi bice birashobora kwibasira ingirabuzimafatizo zihariye hamwe ningingo, kuzamura ibiyobyabwenge murwego rwibibyimba. Shandong Baofa Kanseri Ikigo cyubushakashatsi https://www.baofahospasdatan.com/ ni ku isonga ry'ubu bushakashatsi.

Gutanga ibiyobyabwenge

Liposomes ni scsherical vesticles igizwe na Bilayopide Bilayipite Bilayelipide ishobora kwangiza abakozi batandukanye. Batanga uburinzi bwo gutesha agaciro kandi barashobora kuzamura igihe cyo kugabanyirizwa ibiyobyabwenge. Byongeye kandi, Liposomes irashobora guhindurwa kugirango ikore ingirabuzimafatizo zihariye cyangwa imyenda, kuzamura ibiyobyabwenge kurubuga. Docetaxel, akoreshwa cyane imiti ya chimiotherapy, akenshi ikorwa muburyo bwa liposoman kugirango itezimbere imikorere yayo kandi igabanye ingaruka.

Inyungu n'imbogamizi z'ibiyobyabwenge biteganijwe

Icyerekezo kizaza mu gutanga ibiyobyabwenge bya kanseri

Ubushakashatsi bukomeje bwibanda ku iterambere ryinshi Kuvura ibiyobyabwenge Sisitemu ifite uburyo bwiza bwo kwibasirwa, bwagabanijwe uburozi, kandi bukongerwa imbaraga zo kuvura. Ibi bikubiyemo gushakisha igitabo cyibasiye ligands, gukoresha uburyo bwo gutekereza bwambere bwo gukurikirana ibiyobyabwenge, no guteza imbere uburyo bwihariye bushingiye kubiranga umuntu ku giti cye. Kwishyira hamwe kwa NanoteChOlogy na Umununotherapie itanga isezerano rikomeye ryiterambere ryiterambere ryumurima.

Iterambere no gushyira mubikorwa bifatika Kuvura Ibiyobyabwenge Gutanga Ibitaro bya kanseri Ikeneye ubufatanye bwihuse hagati y'abashakashatsi, abaganga, n'ibigo bya farumasi. Gukomeza ishoramari mubushakashatsi niterambere ningirakamaro kugirango uhindure amatote kugirango wita ku yihangana no kwitabwaho.

¹ Amakuru namakuru atandukanye mubinyamakuru bitandukanye bya siyansi hamwe nurubuga rwa farumasi. Ibisobanuro byihariye biboneka bisabwe.