Kunzwisisa uye Kugadzirisa Triple-Isina Mbiru Yekenza yeChina

Iyi gwara rakazara rinotsvaga kuoma kwe China triple-isiriyo yechipfuva kenza. Isu tinodzungudza mukutanga kufambira mberi uye kukurukura kukosha kwekutanga kwekuona uye kurongeka kwekutarisirwa. Dzidza nezve rutsigiro zviwanikwa uye nzvimbo yekuvandudza ye Trincer Trincer Cancer kurapwa mukati meiyo Chinese hutano hwehutano hwehutano.

Prearence uye njodzi zvinhu zvevakapetwa katatu-kongiri yechipfuva muChina

Kunzwisisa Katatu-Yakashata Mazamu Cancer

Trincer Cancer yemazamu (TNBC) Icho chidimbu chegomarara remazamu izvo zvinoshaya mazwi matatu: Estrogen Receptor (ER), Progesterone Receptor (pr) Uku kusavapo kunoita kuti ive nehasha uye kunetsa kurapa zvichienzaniswa nedzimwe cancer tencer. Iko kushomeka kwezviitiko izvi kunoreva kuti zvinozivikanwa zvinorema hazvishande, zvinokonzeresa kuvimba nemakemotherapy, kuvhiyiwa, uye radiation.

Prevalence muChina

Nepo magwaro epamusoro anosiyana, zvidzidzo zvinoratidza kuti kuwanda kwe TNBC muChina yakafanana neyekuti kana zvishoma zvakakwirira kupfuura izvo kumadokero kwevanhu. Izvi zvinoratidzira kukosha kwekuwedzera kwekuziva uye nekuvandudzwa kwekuwana kuongororwa uye kurapwa mukati meiyo Chinese hutano hwehutano. Kuwedzera kutsvagisa kwakakosha kuti unzwisise zvakananga genetic uye zvakatipoteredza njodzi zvinhu zvinopa kuwanda kwekuwanda kweChina.

Zvinhu zvine njodzi

Zvinhu zvinoverengeka zvinowedzera njodzi yekukudziridza TNBC, kusanganisira zera diki pakuongororwa, brca1 / 2 genetic bvunzo dzinogona kubatsira kuziva izvi kuzvikoro), kunyangwe kukanganisika kwechiChinese kwechiChinese kunoda kuwedzera kuongorora), uye nhoroondo yemhuri yekenza yemazamu. Zvinhu zvehupenyu sekufutisa uye kushaya basa remuviri kungatambawo basa. Izvo zvakakosha kuti ubvunze nehutano hwehutano hwekuongororwa kwakarongeka kwehuwandu hwekuongororwa.

Kuongororwa uye sarudzo dzekurapa

Kubvira kwekutanga kukoshesa

Kuongororwa kwekutanga kunovandudza kunoita prognosis ye TNBC. Kugara uchizvikudza pachako-bvunzo, mammograms (kunyanya kune vakadzi vanopfuura makumi mana), uye kukurudzira kurapwa kuti chero chipi zvacho zvachinja mazamu anokosha. Iyo Shandong Baoma cancer Research Information Institute (https://www.bhabohanaleptal.com/) Inopa Yepamberi Yekuongorora Sevhisi yegomarara rekenza.

Kurapwa kunosvika

Kurapwa kwe TNBC kazhinji inosanganisira kusanganiswa kwenzira:

• Kuvhiya: Lumpectomy kana mastectomy, zvichienderana nehukuru hwaTumor uye nzvimbo.
• Chemotherapy: Inoshandiswa kudzima tumors isati yavhiyiwa (neoadjuvant) kana mushure mekuvhiyiwa (Adjuvic (Adjuvic (Adjuvic (Adjuvic (Adjuvic (Adjuvic (Adjuvic (Adjuvic (Adjuvic (Adjuvic) kubvisa masero akasara ekanza.
• Radiation Kurapa: Target cancer masero mushure mekuvhiyiwa kuti udzivise kudzokorora.
• Target Intapige: Nepo tsika dzakarongedzwa marapirwo adzisingakwanisi kurwisa TNBC Nekuda kwekushayikwa kwekutarisa kutaura, kutsvagisa kuenderera mberi kunotora ruzha rwakatarisana nekurapa. Immamuritherapy zvakare iri nzvimbo inokura yekutsvaga uye kurapwa.

Kuenderera mberi kwekutsvaga uye ramangwana mirayiridzo

Miedzo yekiriniki uye kufambira mberi

Kufambira mberi kwakakosha kuri kuitwa mukunzwisisa uye kurapa TNBC. Miedzo yakawanda yekiriniki iri kuenderera kuChina uye pasi rose, kuongorora mishonga mitsva uye maratidziro ekurapa. Iyi miedzo inopa tariro yezvinyorwa zvakavandudzwa uye zvirongwa zvekurapa zvakarongeka.

Basa reGenomics uye mushonga wakasarudzika

Genomic ongororo iri kubatsira kuziva zvakananga genetic muutsican drive TNBC, achiridza nzira yekuita zvakanyanya kurapwa. Izvi zvinobvumidza kurapa kwakadzvanywa kwakavakirwa pane mumwe nemumwe maitiro emurwere uye genetic profiles. Ramangwana re TNBC kurapwa kunorara mumushonga wakanyorova.

Tsigiro uye Zviwanikwa

Kutarisana neKuongororwa kwe TNBC inogona kuve yakaoma. Mapoka anotsigira, mabasa ekupa zano, uye masangano emurwere emurwere anopa rubatsiro runokosha. Kuwanika kune ruzivo rune mukurumbira uye kuenderera mberi rutsigiro rwekurapwa kwakakosha kwekufamba rwendo urwu. Rangarira, kutanga kuona uye kuwana kune hutano hutano hutano hunokanganisa.

Mhedziso

China triple-isiriyo yechipfuva kenza Zvipo zvakakura, asi zvichiratidzika uye kufambira mberi mukurapwa kunopa tariro yakavandudzwa. Kuona kwekutanga, kurapa kwakasarudzika kuswedera, uye kuwana zvekutsigira zviwanikwa zviri kutsigira hupenyu hwevanhu vakabatwa neiyi hutsinye hwegomarara remazamu. Iyo Shandong baofCan cancer research Institute institute inotsaurwa kuti ichipa kutarisirwa kwakazara uye kufambira mberi kwevarwere ne TNBC.