genetic mutation lung cancer kurapwa

Kunzwisisa Basa re genetic mutation lung cancer kurapwa inokosha yekuvanzika uye inoshanda cancer cancer manejimendi. Chinyorwa ichi chinoongorora kuti genetic inoedza sei sarudzo dzekurapa, mhando dzekuzvimiririra dzinowanikwa mucanatic cancer cancer. genetic mutation lung cancer kurapwa. Aya maitiro anogona kuitika mumainini anodzora kukura kwesero, kupatsanura uye kugadzirisa. Kuziva izvi kuzvishandura kwakakosha nekuti kunogona kutungamira marongero ekurapa uye kugadzirisa zvabuda murwere. KuSandong Baofa comticer Information Institute, isu tinokoshesa kunzwisisa mamiriro okukura kwegotancape yega yega yemapapu emapuranga. "Ndezvipi zvinhu zvekugadzira genetic?Genetic mutation lung cancer kurapwa vari kufambidzana muzvikamu zvekutevedzana izvo zvinogona kutungamira kune zvisina kujairika maitiro maitiro. Aya maitiro anogona kugarwa nhaka kana kuwanikwa panguva yehupenyu hwemunhu. Mune cancer yemapapu, akawanikwa muchitokisi akajairika uye anowanzo kukonzerwa nezvinhu zvakatipoteredza sekusvuta kana kufumurwa kune zvakasvibiswa. Aya maculies anogona kukanganisa nguva yakajairika cellular maitiro, achitungamira kukura kusingadzoreki uye kuumbwa kwematumon Kunzwisisa izvi kuzvishandura kwakakosha pakusarudza nzira yekurapa kwayo. Heano mamwe ezvakanyanya kuitika:Egfr (epidermal kukura Factor Receptor): Shandura muEgfr zvinozivikanwa mune isiri-diki cell lung cancer (NSCLC), kunyanya muAdenoarcinomas. Aya maitiro anogona kuita cancer cell cell inonzwa zvakanyanya kune mamwe marapirwo akarapwa.ALK (Anaplastic Lymphoma Kinase): ALK rearrzarments ndeyemamwe anovhundusa mutation inowanikwa mu nsclc. ALK Inhibitors yakaratidza kubudirira kwakakosha mukurapa tumors neiyi mutation.Ros1: Zvakafanana neAlk, maRos1 mafungiro anogona kutyaira mapapanza ekukura. Ros1 Inhibitors inowanikwa kune varwere vane ros1-yakanaka nsclc.Braf: Braf shanduro, kunyanya iyo v600e shandisi, inogona kuwanikwa mu nsclc. Braf Inhibitors inogona kushandiswa kunongedza izvi kuzvishandura.KRAN: Kras shanduro dzinozivikanwa muLUNG ADENORINCINGA. Nepo zvakaitika kare zvichinetsa, marapiro matsva ari kubuda kurapa kras-akatunganidzwa mapapiro emapapu.PD-L1 (yakarongerwa rufu-ligand 1): Nepo isiri iyo gene mutation mune yetsika pfungwa, PD-L1 kutaura ndeye biomarker iyo inogona kufanotaura kuti immauriintapy. Yepamusoro PD-L1 Express inogona kuratidza kuti murwere anogona kubatsirwa kubva kumucheto necropotrapy.Genziyo kuongororwa kwegomarara remapapuGenetic mutation lung cancer kurapwa inozivikanwa kuburikidza nekuedzwa kwakazara genetic, inozivikanwawo seBiomarker kuyedza kana mamorekuru. Uku kuyedzwa kuongorora tumor tumor tishu kana, mune zvimwe zviitiko, maratidziro eropa kuratidza zvakananga genetic shanduko dziri kutyaira kuwanda kwe cancer. Mhedzisiro yeiyi bvunzo dzinobatsira Offologists Rakafunga kurapa kuronga kurongedza hunhu hwakasarudzika hwekanasi yemurwere wega wega murwere. Baofa Cancer Information Institute Inoshandisa State-of-The-The-The-The-Art Testinlogies Testinlogies Testsseveral Mhando dzeGenetic bvunzo dzinoshandiswa muLung Cancer Kuongororwa uye Kurapa Kuronga:Inotevera-chizvarwa chekusevha (NGS): NGS ndiyo nzira yakazara yekuyedza iyo inogona kuongorora marudzi akawanda panguva imwe chete. Izvi zvinobvumidza kuongororwa kwehuwandu hwakawanda hwekuzvikamu uye zvimwe zvinoshatisa zvinhu.Polymerase Chain Reaction (PCR): PCR ndiyo yakanyanya kutaridzika nzira yekuyedza iyo inoshandiswa kuona zvakananga maitiro kana gene genera.Fluorescence in Sit Hybridization (hove): Hove inoshandiswa kuona gene gener gener, senge alk uye ros1 dzidziso.Immunhuhistochemistry (IHC): IHC inoshandiswa kuona protein kutaura, yakadai sePD-L1, iyo inogona kubatsira kufanotaura kuti immunomy geneth inofanirwa kuitwa? Kuedzwa kunofanirwa kuitwa nekukurumidza sezvinobvira mukuronga kuronga maitiro kuitira kuti vakarongerwa kurapa kunogona kutariswa kubva pakutanga. Zvakakoshawo kuti uongororezve kana cancer yakafambira mberi kana kana fungidziro nyowani dzekurapa dzikarwa.target genetic mutation lung cancer kurapwa. Aya marapirwo akagadzirirwa kupindira nekukura, kupatsanurana, uye kupararira kwe cancer celers uku kuderedza kukuvara kwemasero akajairwa. Baofa Hospital Commy Spection Spell Inoshandisa Yakanyanya Inonongedzerwa Inosvitswa Kurapa Izvi zvinodhaka zvinovharira chiitiko cheiyo egfr protein, iyo inowanzo nyonganisa mu cancer masero nezvinhu izvi. Zvakajairika EGFR Inhibritor zvinosanganisira:GEFITINIB (IRESSA)Erlotinib (tarceva)Afatinib (gdcfitifif)Osimortinib (tagsso): Kazhinji kurapa kwekutanga-mutsara weEgf-Mutated NSCL.alk Inhibitoral Havira inoshandiswa kubata mapapiro emapapu neAlk rearransge. Izvi zvinodhaka zvinovharira chiitiko cheALK protein, inowanzoita zvisina kujairika mu cancer masero neiyi yekugadziridzwa. Zvakajairika ALK Inhibritor zvinosanganisira:Crizotinib (Xalkorili)Alectinib (Alecensa)Ceritinib (Zykadia)Brigatinib (Alunbrig)Lorlatinib (Lorbrena)Ros1 Inhibitors ... Inhibitors inoshandiswa kubata mapapiro emapapu neRos1 mafungiro. Izvi zvinodhaka zvinovharira chiitiko cheRos1 protein, inowanzoita zvisingaite muCancer masero neiyi pfungwa. Zvakajairika Ros1 Inhibritor zvinosanganisira:Crizotinib (Xalkorili)Entrecechib (rozlytrek)Braft Inhibitrerbitrf Inhibitors inoshandiswa kubata mapapiro emapapu ane braf shandisi, kunyanya v600e shandisi. Izvi zvinodhaka zvinovharira chiitiko cheBrap Protein, iyo inowanzo nyonganisa muChinzana masero ane izvi kuzvishandura. Zvakajairika Braf Inhibritor zvinosanganisira:Dabrafenib (tafinlar)Tretinib (mekinist): Kazhinji inoshandiswa mubatanidzwa naDebrafib.kras g12c inhibitorotororib (lumakrasotororib (lumakrasotororib (lumakrasotororib (lumatib (Krazrasib (Krazati) mimwe mienzaniso Ivo vanoshanda nekuvhara chiitiko cheiyo mutated kras kras preperin.immunototherapy Nepo immamuritrapy haina zvakananga chinangwa genetic mutation lung cancer kurapwa, mamwe marudzi ezvivakwa uye biommars, akadai sePD-L1 kutaura uye bundu rekutengesa mutongo (TMB), anogona kufanotaura kupindura kuti immunotherapy. Varwere vane yakakwira PD-L1 kutaura kana TH High inogona kunge iri mukana wekubatsirwa kubva kumucheto. Ku Shandong Baofa cancer Information Institute, isu tinobatanidza immunomunorapy nedzimwe nzira dzakateedzana. Nyowani dzakarongedzwa kurapa uye immunomothapies iri kugadzirwa uye kuyedzwa mumiedzo yekiriniki. Vatsvagiri zvakare vari kushandawo kuti vazivise nyowani genetic mutation lung cancer kurapwa izvo zvinogona kunangwa nemanyowani ekurapa. Sezvo kunzwisisa kwedu genetics yekanza yemapapu kunovandudzika, tinogona kutarisira kuona kunyange sarudzo dzakarongeka uye dzakarongeka dzevarwere. Shandong baofcer Information Institute yakazvipira kuti irambe iri pamberi peTafura. Alk Protein Bathitein1Cilcinolock ros1 Protein Acrateinbraf V600edabraFenib (Bhuroka Bretinib) BLOCK BRAFRAST G12CSotoras BATE genetic mutation lung cancer kurapwa inokosha kune kuvandudza zvibodzwa kune varwere nekenza yemapapu. Genetic kuyedzwa kunogona kubatsira kuziva zvakananga kuzvitumbuka zvinogona kunangwa nemishonga yakarongeka. Sezvo kunzwisisa kwedu genetic yegomarara remapapu kunoramba kuchikura, isu tinogona kutarisira kuona zvakanyanya zvinobudirira uye zvakanangwa kurapwa kwechirwere ichi chinoparadza. Kushanya Shandong baofa cancer researching Institute Kuti udzidze zvakawanda nezve yedu yekunongedzerwa nzira yekuenda kuCommarcer Cancer.Disiki: Ruzivo urwu nderwezvinangwa zvekudzidzisa chete uye hazvifanirwe kutorwa zano rekurapa. Gara uchibvunza neanokodzera hutano hwehutano hwekuongororwa uye kurapwa kwemamiriro ezvinhu ekurapa.refecendicational cancer institute. www.achrerle.vcxAmerican cancer nzanga. muminhonic.com