Yakatumirwa zvinodhaka zvinodhaka zve cancer: Nhungamiro Yakakwana 

Yakatumirwa zvinodhaka zvinodhaka zve cancer ndeye nzira yekurapa iyo inosimbisa mishonga yakananga panhau yebunako. Iyi nzira inovavarira kusimudzira kushanda kwekurapa uku uchideredza mativi emhedzisiro inowanzobatanidzwa neyechinyakare chemotherapy.

Nhanganyaya kune Localised Dishm Dishm

Cancer cancer marapirwo kunge chemotherapy kazhinji inosanganisira kurongeka kwehurongwa hwekutonga, zvinoreva mishonga inofamba mumuviri wese. Paunenge uchishanda pamasero ekutarisa cancer, nzira iyi inogona zvakare kukuvadza masero ane hutano, anotungamira kune zvakakosha mhedzisiro. Yakatumirwa zvinodhaka zvinodhaka zve cancer inopa nzira yakanyanya kunangwa, ichiendesa mushonga wakananga kune bundu nzvimbo.

Iyi nzira inogona kusanganisira nzira dzakasiyana siyana, kusanganisira:

• Kuraira kwakananga kwezvinodhaka mubundo.
• Kuiswa kwezvinodhaka-eluting misveti kana wafers.
• Kushandiswa kweanonangwa Naneparticles ekuendesa zvinodhaka zvakananga kumasokisi cancer.
• Regional Comotherapy, uko zvinodururwa zvinopihwa kune imwe nzvimbo yemuviri ine bundu.

Zvakanakira Kutumirwa Kwemunodhaka

Yakatumirwa zvinodhaka zvinodhaka zve cancer inopa akati wandei zvakanakira pamusoro pehurongwa hwekurapa:

• Yakaderedzwa mhedzisiro: Nekutarisa mushonga paTumor saiti, kuratidzwa kune hutano hwemateyi hunorerutswa, zvichitungamira kune mashoma uye mashoma mativi emhedzisiro.
• Yakawedzera kusimbisa zvinodhaka paTumor: Kutakura kwenzvimbo kunogona kuzadzisa zvakakwirira zvinodhaka mishonga mukati mebunako, zvinogona kuvandudza kushanda kwekurapa.
• Yakavandudzwa kunaka kwehupenyu hwehupenyu: Yakadzikira mhedzisiro uye yakavandudzwa mabudiro ekurapa anogona kusimudzira zvakanyanya hupenyu hwemurwere panguva yekurapa cancer.
• Zvinogona kusanganisa kurapwa: YEMAHARA YEMAHARA inogona kusanganiswa nedzimwe nzira dzekurapa, dzakadai sekuvhiyiwa, radiation kurapwa, uye systemic chemotherapy, kuzadzisa zvinokanganisa.

Maitiro ezvekutumirwa kwemari yemishonga

Maitiro akati wandei anoshandiswa Yakatumirwa zvinodhaka zvinodhaka zve cancer, imwe neimwe nezvigadzirwa zvayo uye zvaringana zviyero:

Zvakananga jekiseni

Izvi zvinosanganisira kupinza zvakananga zvinodhaka mubundo. Iyo iri nyore uye isingadhuri nzira yakakodzera yakakodzera kune anowanikwa mapundu. Ultrasound kana ct kutungamira kunogona kushandiswa kuve nechokwadi chekuiswa kwakaringana. Mienzaniso inosanganisira jekiseni rehutachiona hwevaTollytic kana chemoithepeutic vamiririri.

Zvinodhaka-eluting magetsi uye wafers

Midziyo iyi inovhenekera zvakananga mukati kana padyo nejira. Ivo vanosunungura mushonga zvishoma nezvishoma nekufamba kwenguva, kupa mari yakasimbiswa yekuraira. Gridel^? Wafers, ine Carmustine (BCNU), iwo muenzaniso unozivikanwa wakashandiswa mushure mekutongwa kwekuvhiya kwehuropi.

NANOPATCICCLICCICLESS

Nanoparticles zvidiki zvidiki zvidiki zvakagadzirirwa kuendesa zvinodhaka zvakananga kuCancer Celcer Celcer Celcer. Vanogona kuunganidzwa kuti vanongedze manhamba akanyanya pamasero emakomputa, achiwedzera kuunganidza zvinodhaka pajasiji nzvimbo uye kuderedza mari yekubvisa. Loschoms, polymeric naneparticles, uye mesimbi nanoparticles inowanzo shandiswa.

Regional chomotherapy

Izvi zvinosanganisira kuendesa komotherapy zvinodhaka kune yakatarwa nzvimbo yemuviri ine bundu. Mienzaniso inosanganisira:

• Hepatic Artery Infusion (hai): Yaishandiswa kurapa cancer yeropa nekuendesa chemopoterapy zvakananga kune chiropa kuburikidza neye hepatic artery.
• Intraperitoneal Chemotherapy (IP): Yaishandiswa kubata cancer yeOvarian nekuendesa komotherapy zvakananga mumudumbu.
• Yakasarudzika Limb Forfusion (ILP): Yaishandiswa kurapa melanoma uye sarcoma yemakumbo nekuparadzanisa kutenderera kwerumende uye kuendesa madhiza akakwira emaketomotrapy zvakananga kunzvimbo yakakanganisika.

Mienzaniso yeAnowonek Yakatumidzwa Kudhakwa muKaruta Kurongeka

Yakatumirwa zvinodhaka zvinodhaka zve cancer inoshandiswa pakurapa kwemhando dzakasiyana dzemishonga cancer. Heano manhamba mashoma:

Brain tumors

Gridel^? Wafers akaiswa muuropi mushure mekuvhiya kwekuvhiya kwegiredhi Golomas. Aya Wafer anoburitsa Carmustine (BCNU), mushonga wepotesherapy, zvakananga mumhepo yekuvhiya, kuuraya chero cancer yemaseru echionana akasara. Chidzidzo chakabudiswa mu * renhau yekiriniki oncology * yakaratidza kuti Glidel^? Wafers yakanyanya kuvandudzwa kupona muvarwere nekutsvagirwa ichangobva kuwanikwa-giredhi gliomas.¹

Chiropa chiropa

Hepatic Artery Infsion (hai) ndiyo dunhu remotherapy maitiro anoshandiswa kubata cancer yeropa. Izvo zvinosanganisira kuendesa komotherapy zvinodhaka zvakananga kune chiropa kuburikidza neye hepatic artery, iyo hombe yeropa kupa chiropa. Izvi zvinobvumira zvakakwirira zvekuvhara kwemushonga kuti usvike pombi uchideredza mativi emhedzisiro. Zvidzidzo zvakaratidza kuti Hai vanogona kunatsiridza kupukunyuka muvarwere vane hushoma hwecheka cancer. Nyanzvi dze Shandong baofa cancer researching Institute kunyatso shandisa maitiro aya.

Ovarian cancer

Intraperitoneal Chemotherapy (IP) inzvimbo yedunhu remotherapy inoshandiswa kubata cancer yeOvarian. Zvinosanganisira kuendesa zvinodhaka zve chemotherapy zvakananga mumudumbu mudumbu, uko kenza yeOvarian inowanzopararira. Izvi zvinobvumira zvakakwirira zvekumanikidza kwemushonga kuti usvike pamakanza masero mudumbu. Zvidzidzo zvakaratidza kuti IP chokotherapy inogona kuvandudza kupukunyuka muvarwere nekanyaya yepamusoro yeOvarian.

Zvinonetsa uye Nzira Dzamangwana

Nepo Yakatumirwa zvinodhaka zvinodhaka zve cancer inopa zvakawanda zvakanaka, kune mamwe matambudziko ekukunda:

• Tumor Heterogeneity: Masero cancer mukati mebundu anogona kuve akasiyana-siyana akasiyana, achiita kuti zviome kutaridzira masero ese zvinobudirira.
• Kudzikisira kwezvinodhaka: Masero cancer anogona kukudziridza kupokana nemishonga inodhaka, kudzikamisa kushanda kwekutakura kwenzvimbo.
• Dhirivhari zvipingamupinyi: Dzimwe tumor dzakaoma kuwana kana kuve nezvipingamupinyi zvemuviri zvinodzivirira zvinodhaka kubva pamasero ese ematehwe.
• Kugadzira uye kuyananisa zvipingaidzo: Kukudziridza uye Kugadzira Local Comm Comms Systems inogona kuve yakaoma uye inodhura.

Kutsvaga mune ramangwana kwakatarisana nekutaura izvi zvinonetsa ne:

• Kukudziridza mamwe maitiro ekutarisa ekurongedza kukurira bundu heterogeneity.
• Kubatanidza Yakatumirwa Kuiswa Kwemishonga nedzimwe nzira dzekurapa, dzakadai secamvothapy uye dzakanangidzirwa kurapa, kukurira kupokana kwezvinodhaka.
• Kukudziridza mitsva madhiragi ekutumira masisitimu ayo anogona kupinda mumatauriri zvakanyanya.
• Kusvibisa iyo yekugadzira uye yekudzora maitiro emidziyo yemari yekuzvitakura.

Mhedziso

Yakatumirwa zvinodhaka zvinodhaka zve cancer Iyi nzira inosimudzira iyo inogona kuvandudza kurapwa kwekurapa uye kuderedza mhedzisiro. Sezvo kutsvagurudzo kunoenderera mberi, nzira iyi ingangoita basa rinowedzera kukosha mu cancer kurapa. Nekutarisira zvinodhaka zvakananga kune bundu saiti, kuendesa kwenzvimbo dzinogona kupa tariro itsva kune varwere vari kurwisa chirwere ichi chinoparadza.

Glossary yeMitemo

Mareferensi

1. Westfal, M., Vakafa, D. C. C., Bortey, E., Del Mastro, R. Fr., 习惯, Comser, M., 2003). Chikamu chechitatu chekutongwa kwenzvimbo yemunharaunda ne biodegradable carmustine (BCNU) WAFERS (GLADEL WAFERS) muvarwere vane mukurumbira glies. * Chinyorwa cheClinical Oncology *, * 21 * (24), 4414-4419.