I-China iRenali Reninoma Pathology

I-China I-Celnal Caltinoma Pathology ichaza i-patology ye-patolomu kwi-CarComa ye-Chinalis ye-Chinalis ye-Chinal Caltolo (i-RCC) eTshayina, igxile kwizifundo eziqhelekileyo, kunye neziphumo zoxilongo. Siza kuphonononga uphando lophando kunye nezikhokelo zeklinikhi ukubonelela ngokuqonda ngokucacileyo lomhlaza oxhaphakileyo. Lo vimba ucelwe ukuba ngoochwephesha bezempilo kunye nabaphandi abanomdla kwi-Rcc Pathology.

Epidemiology kunye nezinto zomngcipheko ze-RCCC e China

I-renali ye-carcinoma ibonisa umngeni obalulekileyo wempilo eTshayina. Ngelixa ichaza izelelo ezichanekileyo zengingqi, izifundo zibonisa imeko ekhulayo, zibonisa iipateni zehlabathi. Izinto ezininzi zomngcipheko zinegalelo kuphuhliso lwe-RCC, kubandakanywa ukutshaya, ukutyeba, uxinzelelo lwegazi kunye nembali yosapho. Ngapha koko, ukuvezwa kwezinto ezithile zemo engqongileyo kungadlala indima. Ukuqonda ezi zinto zobungozi kubalulekile ekusebenzeni ngeendlela zokuthintela.

Ukuhlelwa kwe-pathoical ye-RCC

Eyona tyhefu ye-subtyloginal ye I-China Reaninal Calcinoma I-CCCC ecacileyo ye-RCC (CCHCc), inika ingxelo kubaninzi bamatyala amatyala. Nangona kunjalo, ezinye izinto ezityhutywe, ezinje nge-papillary i-RCC, i-chromophobe i-RCC, kwaye ukuqokelela i-DUCC ye-RCC, yenzeka. Ukucaciswa ngokuchanekileyo kwe-pathoical kubaluleke kakhulu ekukhokeleni izigqibo zonyango kunye nokuqikelela isifo. Ubuchwephesha bamhla, kubandakanya i-Ignohistochemistry kunye ne-moleculating proiling, ziya kuqeshwa ngokuphucula ukuchaneka.

Cima iselfowuni yeseli renali (i-CCRCC)

I-CCRCC iphawuleka nge-cytoplasm ecacileyo kwiiseli ze-tumor ngenxa ye-glycogen ye-glycogen kunye ne-lipidy. Ihlala ibonisa iphethini yezidli eziqinileyo kunye neetyhubhu. Utshintsho oluthile lwemolekyuli, olunjengokuguqulwa kwe-vhlere, kuhlala kunxulunyaniswa ne-CCHCc. Ukuqonda ezi mpawu zemolekyuli kubalulekile ukuze kuthathwe uphuhliso lonyango.

Ezinye izinto eziphantsi kwe-RCC

I-Papillary i-RCC iphawulwa yizakhiwo zePapillaE-njenge-PAPPIL-AFLS ebonisa eyona nto ifanelekileyo kune-CCHC. I-Chromophobe i-RCC ayifani kwaye ibonisa i-soosinophilic ye-leyophilic ye-Eosinophilic. Ukuqokelela i-DUCCRCC yi-subtype enqabileyo nenobundlongondlongo. Umahluko ochanekileyo phakathi kwezi subtypes kubalulekile kwizicwangciso zonyango.

Iindlela zokuxilonga ze-RCCC eTshayina

UKUXHASA I-China Reaninal Calcinoma Ngokwesiqhelo kubandakanya indibaniselwano yezifundo zokucinga (i-CT, Mri) kunye novavanyo lwe-fictophetrolold okanye iisampulu zonyango. Inkqubela phambili kwiindlela zokucinga, kubandakanya i-Multiphasic CT, yandisa ukufunyanwa kunye nokulinganiswa kwezinto ze-renal. I-Aspilous ye-Inapsy yenaliti i-biopsy inokubonelela ngolwazi lwe-cytological cytological, ngelixa i-utyaning thergacal ivumela ukuxilongwa ngokuqinisekileyo.

Izinto eziqinisekileyo kunye neziphumo zonyango

Izinto ezininzi zinefuthe kwi-RCC-progenosis ye-RCC, kubandakanya inqanaba le-tumoor (i-TNM isigaba), iBakala le-teralogical, nobukho be-metastasis. Inkqubo ye-TNM ibonelela ngendlela emiselweyo yokufikelela emngciphekweni. Ngapha koko, inkqubo yokuhlela iFuhrman ivavanya imixholo yenyukliya yeeseli ze-RCC ukuqikelela indlela yokuziphatha. Ezi zinto zikhokelela kwizigqibo zonyango, zisusela kwi-sugoction ye-surgical kwiindlela ezijolise kuzo kunye nemmunotherapy.

Uphando kunye nezikhombisi ezizayo

Uphando oluqhubekayo e-China lujolise ekuphuculeni ukufunyanwa kwangoko, kunye neendlela zokuqonda zokuxilonga, kunye nokuphuhlisa amaqumrhu eNovel I-China Reaninal Calcinoma. Oku kubandakanya uphando kwii-biomarkers ukuba kufunyenwe kwangoko, ukuphononongwa kweethagethi zonyango lweNovel, kunye nezilingo zeklinikhi ezihlola iindlela zokunyanga. Intsebenziswano phakathi kwabaphandi, oonontlalontle, kunye nabaqulunqi bemigaqo-nkqubo kubalulekile ukuqhubela phambili ukuqonda nolawulo lwe-RCCC e China.

Itheyibhuli: Thelekisa i-RCC ye-RCC

Iphepha elichazayo: Olu lwazi luyinjongo zemfundo kuphela kwaye akufuneki kuthathelwe ingqalelo icebiso ngonyango. Soloko unxibelelana nengcali yezempilo ngayo nayiphi na inkxalabo yezempilo okanye ngaphambi kokwenza naziphi na izigqibo ezinxulumene nempilo yakho okanye unyango.

Ukufumana ulwazi oluthe kratya ngophando lomhlaza kunye neenketho zonyango, nceda utyelele IZiko loPhando lweShandong Baeo.