I-metastatitic i-carnali yeseli

I-metastatitic i-carnali yeseli (Mnucc) luhlobo lomhlaza wezintso osasazeke kwamanye amalungu omzimba. Ukhetho lonyango luyahluka ngokuxhomekeke kwinqanaba kunye neempawu ezithile zomhlaza, kodwa zihlala zibandakanya unyango olujolisiweyo, u-gonotherapy, utyando, kunye nonyango lwe-radiation. Ukufunyanwa kwangoko kunye nezicwangciso zonyango ezinobuchule kubalulekile ukuze kuphuculwe iziphumo kwizigulana ezinemibutho ebhalwe kwi-MRCC. Esi sikhokelo sibonelela ngamagqabantshintshi enzulu ye-MRCC, egubungela oonobangela, iimpawu, iindlela zokunyanga, kunye ne-Ponalis, i-Renegalis ye-CarCnoma (i-RCEAL) yeyona ndlela iqhelekileyo yomhlaza wezintso kubantu abadala. Ivela kwi-tube ityhubhu ye-tucule ye-proximal, iityhubhu ezincinci kakhulu kwizintso ezicoca igazi kwaye zisuse iimveliso zenkunkuma. Xa i-RCC ifihlakele, kuthetha ukuba iiseli zomhlaza ziye zaphulukana ne-turum yoqobo kwizintso zezintso, zisasazeka kwamanye amalungu omzimba, ezinje ngemiphunga, amathambo, okanye iBrain. Nje ukuba isasazeke, ihlelwe njenge I-metastatitic i-carnali yeseli . Ukutyeba kakhulu: Ukutyeba kakhulu okanye ukutyeba kuyahambelana nomngcipheko onyukayo. Uxinzelelo lwegazi oluphezulu: Uxinzelelo lwegazi oluphezulu lwegazi lunokonakalisa izintso kwaye unyuse umngcipheko womhlaza. Imbali yosapho: Ukuba nembali yosapho ye-RCC inyusa umngcipheko wakho. Iimeko ezithile ezithethwe njengelifa, ezinjenge-von hindal-lindau (VHL), i-BHL-HOGG-Dube Syndrome, kunye ne-Papillary ye-Partillary i-Parkoma, zidityaniswa nomngcipheko ophezulu. Isifo sezintso okanye isifo sedayisi: Abantu abanesifo esinganyangekiyo, ngakumbi abo banesifo sedayisi, banomngcipheko onyukayo. Ukuvezwa kwiikhemikhali ezithile: Ukuvezwa kweCadmium, i-Trichlorethylene, kwaye ezinye ii-herbicides zinxulunyaniswa ne-rcc.symptoms ze-carcinmatic carcinmaearly-Inqanaba le-RCCIT-Inqanaba le-RCCIT-Inqanaba le-RCCIT-I-RCC-I-RCCE ingenazimpawu. Njengoko ithumba ikhula okanye inokuthi ivele, iimpawu zinokuvela. Ezi zinokwahluka ngokuxhomekeka apho umhlaza usasazeke khona, kodwa iimpawu eziqhelekileyo ze I-metastatitic i-carnali yeseli Quka igazi kumchamo (i-hemauria) Intlungu engapheliyo ecaleni okanye ibuyisa i-vemp okanye i-suble ye-factor ye-facture (ukuba umhlaza uye wasasazwa kwi-anks ye-carcinadic sel I-metastatitic i-carnali yeseli Ngokwesiqhelo kubandakanya ukudityaniswa kweemviwo zokwenyama, ukucinga kunye nokucinga, kunye ne-biopsies. Uvavanyo lomzimba: Ugqirha uya kwenza uvavanyo lomzimba ukukhangela nayiphi na into engaqhelekanga. Ukuvavanya uvavanyo: Iskena se-CT: Iskena se-CT ibonelela ngemifanekiso eneenkcukacha kunye nezicubu ezingqonge kwaye zinokunceda ukuba zifumane ubungakanani kunye nendawo yazo. Mri: I-MRI inokubonelela ngemifanekiso eneenkcukacha nangakumbi kwaye ihlala isetyenziselwa ukuvavanya ubungakanani bomhlaza. I-Bone Scan: Iskena sethambo isetyenziselwa ukukhangela ukuba umhlaza usasazeke emathanjeni. Iskena sezilwanyana zasekhaya: Iskena se-per sinokunceda ukufumana iiseli zomhlaza kuwo wonke umzimba. I-biopsy: I-biopsy ibandakanya ukususa isampulu encinci yezicubu ezivela kwizintso okanye indawo ye-metastatitic yoviwo phantsi kwemakroskopu. Oku kuqinisekisa ukufumanisa isifo se-RCC kwaye sinceda ekumiseleni uhlobo oluthile lwe-RCCE.TRENT entsokheli ye-metastatic carcinatity I-metastatitic i-carnali yeseli Kuxhomekeka kwizinto ezininzi, kubandakanya ubungakanani bomhlaza, impilo yezigulana iyonke, kunye neempawu ezithile zethumba. Izinketho zonyango eziqhelekileyo zibandakanya: I-Therapytity ejolise kumachiza amathamo ajongwayo ekujoliswe kuzo iimolekyuli ezithile ezichaphazelekayo ekuhlululeni kweseli yomhlaza kunye nokusinda. La machiza anokunceda ukhula kancinci ukukhula komhlaza kunye nokuphucula amaxabiso okusinda. Unyango oluqhelekileyo olujolisiweyo lwe-MRCC lubandakanya: I-Vegf ethi (E.GINEB, i-SOZOPINB, i-Axitinib, i-Axitinib, i-Axitinib, i-vegf) ye-vasklib endotheliation ye-vascular endotheli, ebaluleke kakhulu kwi-tumum. I-MTRous inhibitors (E.G., i-Evelimus, i-Temimonimo): La machiza avimba indlela yokukhula kwe-mammalin (i-MTAbolism.immunOtherapy.com.immunopy.com La machiza abonise iziphumo ezithembisayo ekunyangeni uMercc. Ukunyanzelwa okuxhaphakileyo kwi-MRCC kubandakanya: I-Teking Anfinitors (Eivolomab, iPilisumab): La maProundab) Oku kunokunceda ukuphelisa iimpawu kunye nokuphucula umgangatho wobomi. I-Cytoreductive Nephrectomy ibandakanya ukususa isifo esiphambili sezintso nokuba umhlaza uye wasasazeka kwamanye amalungu omzimba. Oku kunokuphucula ukusebenza kolunye unyango.Ukuphalazeka kwendlela yokunyanga unyango kusebenzisa i-ping enamandla-enamandla okubulala iiseli zomhlaza. Ingasetyenziselwa ukukhulula iintlungu okanye ezinye iimpawu ezibangelwa zii-metastatic tumum, ngakumbi emathanjeni okanye kwi-Brain.clineical PlationsSlines Commances lezihlo zovavanyo ezivavanya unyango lomhlaza. Abaguli I-metastatitic i-carnali yeseli inokucinga ngokuthatha inxaxheba kulingo lweklinikhi ukufikelela kwi-premities yokusika i-Propies.Prognosis ye-carcinati ye-carcinaati ye-Recinoathi I-metastatitic i-carnali yeseli Ukuhluka ngokuxhomekeke kwizinto ezininzi, kubandakanya ubungakanani bomhlaza, impilo yesigulana iyonke, kunye nempendulo kunyango. Imbali, i-MRCC yayinengxaki engalunganga, kodwa inkqubela phambili ekuhlaleni ekujoliswe kulo kunye nonyango luye lwaphucule iziphumo kwizigulana ezininzi. Izinto ezinokubangela ukuba i-proginosis iquka i-Catistalitity ye-Candotical ye-Carncital ye-Carcinalium (i-IMDC) i-SORTEATION I-metastatitic i-carnali yeseli inokuba ngumceli mngeni, ngokwasemzimbeni nangokweemvakalelo. Kubalulekile ukuba ube nenkqubo yenkxaso eyomeleleyo kwaye uthathe amanyathelo okulawula iimpawu kunye neziphumo ebezingalindelekanga zonyango. Oku kunokubandakanya: Ulawulo lweentlungu ngeNkxaso-mali yeNkxaso-mali kunye nokuCetyiswa kweNkcazo yoNyango okanye iNkxaso yeGurha yeGrokhnolo ye-Shandong Baofi IZiko loPhando lweShandong Baeo, sizinikezele ekuboneleleni ngononophelo olubanzi noluhlaza olunempumelelo. Sizibophelele ekuqhubeni uphando lomhlaza kunye nokubonelela abaguli ngonyango olunokwenzeka. Iqela lethu le-ocologists enamava, oogqirha bophandengi, kunye nabasebenzi abaxhasayo basebenza kunye ukuphucula izicwangciso zonyango ezizezobuqu kwisigulana ngasinye sigxile ekuphuculeni umgangatho wobomi kunye nokusinda. Sizabalazela ukunikezela inkqubela phambili yomhlaza kunyango lomhlaza, kubandakanya unyango olujolise kulo, ucoceko kunye novavanyo lweklinikhi I-metastatitic i-carnali yeseli iyaqhubeka, ngenjongo yokuphuhlisa unyango olutsha kunye nonyango olululo. Iindawo ezikhoyo zangoku zophando zibandakanya: Ukuphuhlisa unyango olujolisileyo kunye nomonotherapies ochonga ii-biomaskers ezinokuthintela ukuqhubela phambili kweendlela zokunyanga kunye nokuhlaziya izicwangciso zethu zokuqhubela phambili ukuqhubela phambili ekuqondeni izigulana ezinesifo esinengxaki.