I-PANCRORORINICINICINACRY EBALULEKILEYO: Ukuqonda izinto zomngcipheko 

Ukufumanisa ngqo I-pancreatic douspes Kuhlala kungumceli mngeni, kodwa uphando luchonge izinto ezininzi zomngcipheko ezinokwandisa amathuba okuphuhlisa esi sifo. Ezi zinto zisuka kwizigqibo zemfuza kunye nokhetho lwendlela yokuphila kwiimeko zonyango zangaphambili. Eli nqaku libonelela ngamagqabantshintshi ngokubanzi kwezi zinto zinokubangela, ukuhambisa ukuqonda okuxabisekileyo ekuqondeni nasekuthongeni umngcipheko wakho.

Yintoni umhlaza wepancreatic?

I-pancreatic umhlaza sisifo apho iiseli ezingathandekiyo zenziwa kwizicubu zepancreas, ilungu eliziimitha. I-pancreas ivelisa i-enzymes enceda ukugaya ukutya kunye neehomoni ezinceda ukulawula iswekile yegazi. Zimbini iintlobo eziphambili zomhlaza we-pancreatic

Kusekwe I-pancreatic douspes kunye nezinto zomngcipheko

Indalo yemfuza

Ipesenti encinci ye I-pancreatic umhlaza Amatyala anxibelelene notshintsho lwendalo. Olu tshintsho lunokunyusa ubume bomntu ekuphuhliseni esi sifo. Ezinye zeemfuza ezinxulumene nomngcipheko owondisiweyo zibandakanya:

• I-brca1 kunye ne-brca2: Ezi zihlobo zidibene nebele kunye nomhlaza we-ovarian.
• I-Palb2: Le misebenzi yemfuza kunye ne-brca2 ukulungisa i-DNA eyonakeleyo.
• I-ATM: Le gene ibandakanyeka kulungiso lweDNA kunye nolawulo lweseli.
• I-lynch syndrome genes (MLH1, MSH2, MS2, PMS2, EPCEAM): Esi sifo sonyusa umngcipheko wokuba ngumfundisi oliqela, kubandakanya nomhlaza we-pancreatic.
• I-P16 / CDKN2A: Olu velo lunceda ukulawula ukukhula kweseli.
• Stk11: Ukunxulunyaniswa ne-peutz-jeers syndrome, ebangela i-polyps kwitreyithi yokugaya kwaye yonyusa umngcipheko womhlaza.

Izinto zokuphila zokuPhila

Ukhetho oluthile lwendlela yokuphila lungayichaphazela kakhulu umngcipheko wakho wokukhula I-pancreatic umhlaza:

• Ukutshaya: Ukutshaya yenye yezona zinto zinomngcipheko kakhulu I-pancreatic umhlaza. Abantu abatshayayo baphindwe kathathu kangangethuba lokukhulisa esi sifo xa kuthelekiswa nabangatshayi. Ukuyeka ukutshaya kunokunciphisa umngcipheko wakho ngokuhamba kwexesha.
• Ukutyeba kakhulu: Ukutyeba kakhulu okanye ukutyeba, ngakumbi ukuba neflamu engapheliyo, kunxulunyaniswa nomngcipheko owandisiweyo we I-pancreatic umhlaza. Ukugcina ubunzima bempilo ngokutya kunye nokuzilolonga kubalulekile.
• Ukutya: Ukutya okuphezulu kwi-red kunye ne-mets eqhotyoshelweyo kwaye iphantsi kwiziqhamo kunye nemifuno inokunyusa umngcipheko. Gxila kwizityebi ezixabisekileyo ezityebileyo kwi-great protein, iproteni, iziqhamo kunye nemifuno.
• Ukusetyenziswa kotywala: Ukuselwa kotywala obukhulu, ngakumbi xa kudityaniswa nokutshaya, kudityaniswe nomngcipheko onyukayo.

Iimeko zoNyango

Ezinye iimeko zonyango zinokuphakamisa umngcipheko we I-pancreatic umhlaza:

• Iswekile: Isifo seswekile ende, ngakumbi uhlobo lweswekile 2 lesifo seswekile, linxulunyaniswa nomngcipheko ophezulu. Nokuba iswekile sisizathu okanye uphawu lokuqala lwe I-pancreatic umhlaza isephantsi kophando.
• I-pancreatiitis ye-CHCCreatie: Ukuvunywa kwexesha elide kwepancreas kunokwandisa umngcipheko, ngakumbi kubantu abane-vancreatitis yelifa.
• Imbali yosapho: Ukuba nembali yosapho ye I-pancreatic umhlaza Yongeza umngcipheko wakho, ngakumbi ukuba izale zazalamane ziphelelwe lixesha. Oku kunokubonisa ukubakho kobuso obufundileyo obuzuze njengelifa.
• Ubudala: Umngcipheko we I-pancreatic umhlaza inyuka ngeminyaka. Uninzi lwamatyala kufunyaniswa ukuba abantu ngaphezulu kweminyaka engama-65.
• Ugqatso: Abantu base-Afrika baseMelika banomngcipheko ophezulu wokukhulisa I-pancreatic umhlaza xa kuthelekiswa neCaucasians. Izizathu zokungafaniyo aziqondakali ngokupheleleyo kodwa zinokubandakanya imfuyo, yezentlalo noqoqosho, kunye nendlela yokuphila.

Izinto ezingalunganga zomngcipheko

Ngelixa kuxhaphake, ezi zinto zinokufaka igalelo kuphuhliso lwe I-pancreatic umhlaza:

• Ukuvezwa kwiikhemikhali ezithile: Ukuboniswa ixesha elide kwizitshabalalisi ezithile, iidaya, kunye neekhemikhali ezisetyenziswa ekusebenzeni ngokwesinyithi kunokunyusa umngcipheko.
• I-Hylobacter Pylori (H. Pylori) Usulelo: Olunye uphando lubonisa ikhonkco phakathi kwe H. Pylori Usulelo, olunokubangela izilonda zesisu, kunye nomngcipheko owonyukayo we I-pancreatic umhlaza.
• Isibindi seRiverhosis: Ukuqina kwesifo, okanye ukuncipha kwesibindi, kunokwandisa umngcipheko.

Unakho I-pancreatic umhlaza ithintelwe?

Ngelixa akukho ndlela iqinisekileyo yokuthintela I-pancreatic umhlaza, ungathabatha amanyathelo okunciphisa umngcipheko wakho ngokugxila kwimiba yomngcipheko esebenzayo:

• Yeka ukutshaya: Le yeyona nto ibaluleke kakhulu onokuyenza ukunciphisa umngcipheko wakho.
• Gcina ubunzima obunempilo: Yitya ukutya okulinganayo kunye nokuzivocavoca rhoqo ukugcina ubunzima obusempilweni.
• Umda wokusetyenziswa kotywala: Ukuba usela utywala, yenza njalo ngokumodareyitha.
• Lawula iswekile: Sebenza kunye nogqirha wakho ukuba ulawule iswekile yakho.
• Qwalasela ingcebiso yemfuza: Ukuba unembali yosapho eyomeleleyo ye I-pancreatic umhlaza OKANYE UKUHLAZIYWA KWABASEBENZI BENKQUBO, Qwalasela ingcebiso ngomfuzo yokuvavanya umngcipheko wakho.

UPhando kunye nokuNgenwabela kwiShandong BaookA IZiko loPhando

Kwi IZiko loPhando lweShandong Baeo, sizinikezele ekuphuculeni ukuqonda kunye nonyango lomhlaza, kubandakanya I-pancreatic umhlaza. Uphando lwethu lujolise ekuchongeni iithagethi zonyango lweNovel, ekuhlaleni izixhobo zokuxilonga, kunye nokuphucula iziphumo zesigulana. Sizimisele ukuguqulela uphando-olwenziweyo kwizicelo ezisebenzayo ezixhamla izicelo kwihlabathi liphela. Iqela lethu leengcali lisebenza ngokungakhathali ukukhangela ubunzima bebhayoloji yomhlaza kunye nokuphuhlisa unyango olusebenzayo kwesi sifo sinzima. Sikholelwa ukuba ngophando olusebenzisanayo kunye nokuzinikela kwi-Instion, sinokwenza impembelelo ebalulekileyo kumlo wokulwa I-pancreatic umhlaza.

Ukuqonda umngcipheko wakho kunye nokufuna ingcebiso kwezonyango

Kubalulekile ukukhumbula ukuba ukuba nento enye okanye engaphezulu yomngcipheko akuthethi ukuba uya kuphuhlisa I-pancreatic umhlaza. Abantu abaninzi abanezinto zomngcipheko akaze bafumane esi sifo, ngelixa abanye bengekho bantu bomngcipheko. Ukuba ukhathazekile ngomngcipheko wakho, thetha ugqirha wakho. Banokuvavanya izinto zakho zomngcipheko ngamnye kwaye bacebise uvavanyo olufanelekileyo okanye iindlela zokubeka iliso. Ukufunyanwa kwangoko kunye nokuxilongwa kubalulekile ukuze kuphuculwe iziphumo kwi I-pancreatic umhlaza unyango.

Iindlela zokuxilonga

Ukufunyanwa kwangoko kwe I-pancreatic umhlaza kubalulekile ekuphuculeni iziphumo zonyango. Iindlela ezininzi zokuxilonga zisetyenziselwa ukufumana kunye nenqanaba lesi sifo:

• Ukucinga kuvavanyo:
  • I-CT Scan (i-computer id tomography): Ibonelela ngemifanekiso eneenkcukacha ze-pancreas kunye ne-organs ejikelezileyo, inceda ekuchongeni amathumba.
  • I-MRI (i-Magnetic Reming): Sebenzisa amasimi e-magnetic kunye namaza erediyo ukwenza imifanekiso eneenkcukacha zepancreas kwaye inokuba luncedo ekufumaneni amathumba amancinci.
  • I-Endoscopic ultrasound (eus): Kubandakanya ukufaka ityhubhu ecekeceke, eguqukayo eneprojekhthi ye-ultra I-EUS inokusetyenziselwa ukuqokelela iisampulu zezicubu ze biopsy.
  • Iskena sasekhaya (i-Popitron iphakamisa i-tomography): Ihlala isetyenziswa ngokudibeneyo ngeskena ye-CT ukufumana iiseli zomhlaza kuwo wonke umzimba.
• I-biopsy:
  • I-Inpiration yenaliti (FNA): Inaliti ecekeceke ifakwe kwi-pancreas yokuqokelela iiseli zohlalutyo.
  • I-biopsy ye biopsy: Kubandakanya ukonakala ngokususa isampulu ye-tishu kwi-pancreas yoviwo. Oku kuhlala kwenziwe xa ezinye iindlela azinakwenzeka okanye zigqibelele.
• Uvavanyo lwegazi:
  • I-Tumor Markers: Ezinye izinto, ezinjenge-ca 19-9, ziphakanyisiwe kwabanye abantu I-pancreatic umhlaza. Nangona kunjalo, aba makikishi abasoloko bechanekile kwaye bahlala besetyenziswa ngokudibeneyo kunye nolunye uvavanyo lokuqonda.

Izinketho zoNyango

Unyango I-pancreatic umhlaza Kuxhomekeka kwinqanaba kunye nendawo yomhlaza, kunye nempilo epheleleyo yesigulana. Izinketho zonyango eziqhelekileyo zibandakanya:

• Utyando:
  • Inkqubo ye-whiple (pancreaticuodedenectoy): Kubandakanya ukususa intloko ye-pancreas, inxalenye yamathumbu amancinci, i-gallbladder, kunye nenxalenye yesisu.
  • I-Direcreatectomy: Ukususwa komsila kunye nenxalenye yomzimba weepancreas.
  • Iyonke i-pancreatectomy: Ukususwa kwazo zonke iipancreas. Oku kungaqhelekanga kodwa kunokuba yimfuneko kwezinye iimeko.
• I-chemotherapy:
  • Sebenzisa iziyobisi ukubulala iiseli zomhlaza okanye ukhula lwabo banciphise. I-chemotherapy inokusetyenziswa ngaphambi okanye emva kotyando, okanye njengonyango oluphambili ukuba lo utyando aluyiyo inketho.
• Unyango lwe-radiation:
  • Sebenzisa imitha yamandla aphezulu ukubulala iiseli zomhlaza. Unyango lwe-radiation lungasetyenziswa ngaphambi okanye emva kotyando, okanye njengonyango oluphambili.
• Unyango olujolise kulo:
  • Sebenzisa iziyobisi ezijolise kwiimolekyuli ezithile ezichaphazelekayo ekukhuleni kweseli yomhlaza kunye nokusinda.
• Immunoherapy:
  • Inceda amajoni omzimba alwa iiseli zohlaza. Immunotherapy ayisetyenziselwanga I-pancreatic umhlaza Kodwa kunokuba yinketho kwezinye iimeko.

Ixabiso lokusinda

Amaxabiso okusinda I-pancreatic umhlaza yahluka ngokuxhomekeka kwinqanaba lokufumanisa isifo kunye nonyango olufunyenweyo. Ukufunyanwa kwangoko kunye nonyango kubalulekile ukuze kuphuculwe iziphumo zokusinda. Ngokutsho koMbutho woMhlaza waseMelika, inqanaba leminyaka emi-5 yokusinda kwikhaya I-pancreatic umhlaza (Umhlaza ongasasazikanga ngaphandle kwepancreas) malunga ne-44%. Nangona kunjalo, malunga ne-12% ye I-pancreatic umhlaza Amatyala afunyaniswa ngeli nqanaba. Ngomhlaza osasazeke kumalungu akufuphi okanye izicubu, iqondo lokuphila eli-5 limalunga ne-12%. Ngomhlaza osasazeke kwiindawo ezikude zomzimba, izinga leminyaka emihlanu lokuphila malunga ne-3%. Uxilongo lwangasekuqaleni kwi-Shandong Baesood Baeda IZiko loPhando lweZiko lonyusa inqanaba lokusinda.

La manani aluqikelela kwaye ayohluka ngokuxhomekeke kwiimeko zabantu. Kubalulekile ukuxoxa nge-progunosis yakho kunye nogqirha wakho ukuba uqonde imeko yakho ethile.

Uphando oluqhubekayo

Abaphandi basebenzela ukuphucula isifo kunye nonyango I-pancreatic umhlaza. Iindawo zophando oluqhubekayo zibandakanya:

• Ukuphuhliswa konyango olutsha kunye nokusebenza ngakumbi, kubandakanya unyango olujolise kuwe kunye nomonotherapies.
• Ukuchonga ii-bimarskars zokufunyanwa kwangoko kunye nokuphakamisa.
• Ukuqonda imeko yemfuza kunye nemolekyuli ye I-pancreatic umhlaza.
• Ukuphucula ubuchule bokuhlinzwa.

Ukuqukumbela

Ukuqonda amandla I-pancreatic douspes Kwaye izinto zomngcipheko zinika amandla ukuba wenze izigqibo malunga nempilo yakho. Ngelixa ezinye zezinto ezinomngcipheko, ezinje ngemfuza, zingaphaya kolawulo lwakho, zamkela indlela yokuphila esempilweni kwaye besebenza ngokusondeleyo nogqirha wakho banokunciphisa kakhulu umngcipheko wakho. Izazinzulu kunye namagqirha kwi-Shandong Baeo Book IZiko leMfundo linikezelwe ekuqhubeni ukuqonda kwe I-pancreatic umhlaza kunye nokuphucula unyango olusebenzayo. Hlala unolwazi, ubeke phambili impilo yakho, kwaye unxibelelane nabasebenzi bezempilo ukuze bakhokele.

Iphepha elichazayo: Eli nqaku libonelela ngolwazi ngokubanzi kwaye akufuneki kuthathelwe ingqalelo icebiso ngonyango. Nxibelelana nengcali yokhathalelo lwempilo oluqeqeshiweyo ukuze ufumane isikhokelo kunye nokukhetha unyango.

Imithombo:

1. Umbutho woMhlaza waseMelika: www.cancerr.org
2. IZiko loNcedo lweSizwe: www.cancer.gov
3. Inethiwekhi ye-pancreatic yomhlaza: www.panan.org