Unyango lomhlaza we-pancreatic: Isikhokelo esibanzi 

Unyango lomhlaza we-pancreatic Iinketho zixhomekeka kwinqanaba kunye nendawo yomhlaza, kunye nempilo yesigulana iyonke. Unyango oluqhelekileyo lubandakanya utyando, i-chemotherapy, unyango lwe-radiation, kunye nonyango olujolise kuyo. Rhoqo, indibaniselwano yezi ndlela isetyenziselwa ukufikelela kwiziphumo ezilungileyo. Ukuqonda ezi ndlela zikhethiweyo kubalulekile ukuze kuthathwe izigqibo.

Ukuqonda umhlaza we-pancularic

I-pancreas lilungu elisemva kwesisu elidlala indima ebalulekileyo ekuphengeni kunye nommiselo weswekile yegazi. I-pancreatic umhlaza Kwenzeka ntoni xa iiseli ezikwipancreas zikhula ngokungalawuleki, zenza ithumba. Zimbini iintlobo eziphambili ze I-pancreatic umhlaza: Adenocarcinoma (olona hlobo luqhelekileyo) kunye ne-neuroendongombo

Izinto zomngcipheko zomhlaza we-pancreatic

Izinto ezininzi zinokonyusa umngcipheko wokukhula I-pancreatic umhlaza, kubandakanya:

• Ukutshaya
• Isifo seswekile
• Ukutyeba kakhulu
• I-pancreatisis ye-ticreatitis
• Imbali yosapho ye I-pancreatic umhlaza
• I-syndromes ethile yemfuza

Iimpawu zomhlaza we-pancreatic

Kwinqanaba lokuqala, I-pancreatic umhlaza ihlala inempawu ezibonakalayo. Njengoko umhlaza uyakhula, iimpawu zinokubandakanya:

• Intlungu zesisu
• I-jaundice (ityheli lolusu kunye namehlo)
• Ukuhla ukusinda
• Ukuphulukana nokutya
• Isicaphucaphu kwaye sigale
• UTSHINTSHO KWI-CABITS YAKHO
• I-New-Onset Diabetes

Uxilongo lwe-pancreatic lomhlaza

Ukuba I-pancreatic umhlaza Ukrokrelwa, ugqirha uya kwenza uvavanyo lomzimba kwaye oda lovavanyo, kubandakanya:

• Uvavanyo lwegazi: Ukujonga umsebenzi we-Silr kunye nabamakishi.
• Ukuvavanya uvavanyo
• I-biopsy: Ukuqinisekisa ukuxilongwa kwaye kuchongwe uhlobo lwe I-pancreatic umhlaza.

I-pancreatic yomhlaza onyango

Unyango lwe I-pancreatic umhlaza Kuxhomekeka kwizinto ezininzi, kubandakanya inqanaba lomhlaza, indawo ayo, kunye nempilo yesigulana iyonke. Olona khetho luphambili lonyango luchazwe ngezantsi. IZiko loDumelo leShandong Bae AOOOCY Unga Funda ngakumbi apha malunga nendlela yabo.

Utyando

Utyando luhlala luphawu lodidi lokuqala I-pancreatic umhlaza Ukuba i-tumar ifikile kwaye ayisasazi amanye amalungu. Iinkqubo ezahlukeneyo zoqhaqho zinokusetyenziswa ngokuxhomekeke kwindawo ye-tumar:

• Inkqubo ye-whippen (i-pancreaticudeguode): Oku kubandakanya ukususa intloko ye-pancreas, inxalenye yamathumbu amancinci, i-gallbladder, kunye nenxalenye ye-bile duct.
• I-Direcreatectotectomy: Oku kubandakanya ukususa umsila weepancreas kwaye kunokubandakanya i-spleen.
• Iyonke i-pancreatectomy: Oku kubandakanya ukususa zonke i-pancreas, i-spleen, i-gellbladder, inxenye yesisu, kunye nenxalenye yamathumbu amancinci. Oku kuyinto engaqhelekanga.

Nokuba i-turum ingasuswa ngempumelelo ixhomekeke kwindawo nangenqanaba layo. Le yinto ebalulekileyo ekuqinisekiseni iindlela zonyango. Ingcali yoNyango inokuchaphazela kakhulu iziphumo, ukwenza amaziko anjenge-shandong baook yophando loPhando lweZibonelelo eziphambili kwizigulana.

Chemotherapy

I-chemotherapy isebenzisa iziyobisi ukubulala iiseli zomhlaza. Ingasetyenziswa ngaphambi kotyando (i-neaadjualjuracy chemotherapy), emva kotyando (i-chemotherapy), okanye njengonyango oluphambili I-pancreatic umhlaza. Iziyobisi eziqhelekileyo ze-chemotherapy ezisetyenziselwa ukunyanga I-pancreatic umhlaza Faka:

• IGemcitabine
• I-Foferinox (indibaniselwano ye-fluorouracil, i-leucovrin, i-Irinotecan, kunye ne-ongulalipn)
• I-abraaxane (paclitaxel iproteyini)

I-chemotherapy inokubangela iziphumo ebezingalindelekanga, ezinjenge-nausea, ukugabha, ukudinwa kweenwele, kunye nelahleko yeenwele. Ezi ziphumo zisecaleni zihlala zilawulwa ngamayeza kunye nokuxhasa ukhathalelo.

Unyango lwe-radiation

Unyango lwe-radiation lonyango lusebenzisa imitha yamandla aphezulu ukubulala iiseli zomhlaza. Ingasetyenziswa ngaphambi kotyando, emva kotyando, okanye njengonyango oluphambili lwe I-pancreatic umhlaza. Iindidi zonyango lwe-radiation ibandakanya:

• I-radiation ye-radiation yebhiya yangaphandle (i-EBRT): Imitha inikezelwa kumatshini ngaphandle komzimba.
• I-Brachytherapy: Imbewu yerediyo ibekwe ngqo kwi-tumar.

Unyango lwe-radiation lunokubangela iziphumo ebezingalindelekanga, ezinjengokucaphuka kolusu, ukudinwa, kunye nesicaphucaphu.

Unyango olujolise kunyango

Unyango olujolise kunyango lusebenzisa iziyobisi ezijolise kwiimolekyuli ezithile ezichaphazelekayo ekukhuleni kweseli yomhlaza kunye nokusinda. Imizekelo ye-carapies ekujoliswe kuyo esetyenziselwa ukunyanga I-pancreatic umhlaza Faka:

• I-EROTONIniB: Ithagethi I-Eceradeli yokukhula
• I-Olaparib: Ithagethi I-Parp Enzyme kwizigulana ezine-brca eziguqukayo.

I-gonotherapy

Umgono unceda amajoni akho omzimba alwa nomhlaza. Ayisetyenziswanga njengonyango lomgca wokuqala I-pancreatic umhlaza Kodwa kunokuba yinketho kwiimeko ezithile. I-Pembromizumab (I-Indirtrida) lichiza elimlumyo elinokusetyenziselwa I-pancreatic umhlaza Izigulana ezinolwazi oluthile lwendalo.

Inkathalo ye-pallitive

Inkathalo ye-pallietive igxile ekupheliseni iimpawu kunye nokuphucula umgangatho wobomi kwizigulana ezinesifo esinezifo ezinamandla, ezinje I-pancreatic umhlaza. Inkathalo ephangiweyo inokubandakanya ulawulo lweentlungu, inkxaso yesondlo kunye nenkxaso yeemvakalelo.

Amanqanaba omhlaza we-pancreatic kunye neendlela zonyango

I-pancreatic umhlaza Ilungiselelwe ukufumanisa ubungakanani bomhlaza kunye nezigqibo zonyango. Amanqanaba avela kwinqanaba le-0 (Umhlaza kwi-IV) kwiNqanaba le-IV (Umhlaza waseMetatitic). Le theyibhile ilandelayo ishwankathela iindlela zonyango kwinqanaba ngalinye:

Ukuhlala nomhlaza we-pancreatic

Ukuhlala nayo I-pancreatic umhlaza kunokuba ngumceli mngeni, kodwa kukho izibonelelo ezikhoyo zokunceda abaguli kunye neentsapho zabo iintsapho. Amaqela enkxaso, ukucetyiswa, kunye neenkqubo zemfundo kunokunika uncedo olubalulekileyo. Ukugcina indlela yokuphila esempilweni, kubandakanya ukutya okulinganayo kunye nokuzilolonga rhoqo, kunokuphucula ubomi.

Indima yovavanyo lweklinikhi

Iimvavanyo zeklinikhi zizifundo zophando ezivavanyayo Unyango lomhlaza we-pancreatic iindlela zokusondela. Ukuthatha inxaxheba kwityala leklinikhi kunokubonelela ngokufikelela kwiindlela zokucheba umphetho kunye negalelo kwinkqubela phambili yoKhathalelo loMhlaza. Izigulana zinomdla kwiimvavanyo zeklinikhi kufuneka zixoxe ngethuba kunye neqela labo lezempilo.

Ukuqukumbela

Unyango lomhlaza we-pancreatic inzima kwaye ifuna indlela yethutyana. Ukuqonda iindlela ezikhoyo zonyango, amanqanaba, kunye nezixhobo zokuxhasa amandla okunika amandla izigulana ukuba enze izigqibo ezinolwazi kunye nokuphucula iziphumo. Soloko unxibelelana nomboneleli wakho wezempilo ukufumanisa eyona khosi ilungileyo yonyango kwimeko yakho ethile. Ngeqela elizinikeleyo kwi-shandong baook yophayisi lomhlaza, ngokuqinisekileyo baya kuthathwa yimfesane nobungcali.

Iphepha elichazayo: Eli nqaku libonelela ngolwazi ngokubanzi malunga Unyango lomhlaza we-pancreatic kwaye akufuneki ukuba ithathwe njengengcebiso yonyango. Soloko unxibelelana nengcali yezempilo efanelekileyo yokuchonga isifo kunye neengcebiso zonyango.

Izalathiso:

1. IZiko leSizwe leSizwe. Unyango lwe-pancreatic yomhlaza (PDQ?) - Inguqulelo yesigulana
2. Umbutho woMhlaza waseMelika. Malunga nomhlaza we-pancreatic