Iseli ye-renalin carcinoma pathology

Iseli ye-renalin carcinoma pathology Ibandakanya uvavanyo lwe-microscopic kunye nohlalutyo lwezicubu zezintso ukuze ufumane umhlaza weentso. Linyathelo elibalulekileyo ekuqinisekiseni uhlobo, iBanga, kunye nenqanaba lomhlaza, owazisa izigqibo zonyango kwaye uxela kwangaphambili. Ukuqonda amanqaku ngelingelovimba-ntle kubalulekile kuzo zombini izigulana kunye neengcali kwezonyango. Esi sikhokelo sinikezela ngamagqabantshintshi eneenkcukacha ze Iseli ye-renalin carcinoma pathology, kubandakanya imisonto emiselweyo, iinkqubo zokuhlela, isitali, kunye nendima ye-IgonohistochemistsIseli ye-renalic carcinoma (i-rcc) lolona hlobo luqhelekileyo lomhlaza wezintso kubantu abadala, i-accounting malunga ne-90% yazo zonke iintsomi zezintso. Iphakama kwi-tube i-tucule ye-proximal, eneebhubhu ezincinci kwizintso ezicoca igazi kwaye zivelise umchamo. Isifo esichanekileyo sobuchwephesha kunye nokuhlelwa kwe-RCC kukukhokelela kwizicwangciso-nkqubo zonyango kunye ne-PrestyMonsMPles.com yokuqikelela kwi-RANCYPLSEPOLS SURTYELEPLs Subtypes Subtys, nganye inezinto eziphilayo, iimpawu zemfuza, kunye nokuziphatha kwengqondo. Ezi phunga zinokwahlulwa phantsi koviwo lwe-microscopic kwaye ziqinisekiswe ngakumbi yi-uRununohistochemistry. Ezona subtypes ezinkulu zibandakanya: cima iselfowuni ye-Renalin Calcular (i-CCRCc) i-RCCC ecacileyo ye-RCC yelona lixhaphakileyo, inika ingxelo malunga ne-70-80% yazo zonke iimeko ze-RCC. Ibonakaliswa ziiseli ezicocekileyo okanye ze-cytoplasm ecacileyo ngenxa ye-glycogen ephezulu kunye ne-lipid. Ezi seli zihlala zenza iindlwana okanye amashiti, kwaye ithumba liqhelekile kakhulu.papillary renal carcinma (prcc) i-Papillary Rcc PCCE, yenza malunga ne-10-15% yetyala le-RCC. Ibonakaliswa yi-papillary uyilo, okuthetha ukuba iiseli ze-tumor zikhulisa ngexesha elifanelekileyo. Zimbini iintlobo eziphambili ze-PRCC: Uhlobo lwe-1 kunye nohlobo lwe-2. Uhlobo lwe-1 prcc lihlala line-progunopho (chcromophobe i-chromophobe i-RCC imele malunga ne-5% ye-RCC yetyala. Iiseli ze-chcc zine-cytoplalic i-cytoplasm ye-pile kunye ne-pertinuar halo. I-nuclei ihlala ijijeke okanye ingekho mthethweni.Collection Duct I-DACCINA (CDRCCC) yokuqokelela i-DUCC i-DUCCRCC yi-ducc ye-ducc scct i-ducc enqabileyo nenobundlongondlongo. Inika imali engaphantsi kwe-1% yetyala le-RCC. Iiseli ze-tumor zenza i-tubule engekho mthethweni kunye ne-papillae, zihlala zine-Desmopastic stromarialsupal Oku kwahluka kubonakaliswa yi-carcinoma eyahlukileyo engaphandle kwe-infsolmagety efihliweyo. Inkqubo yokuhliswa kwe-fuhrman yayisetyenziswa ngokwesiko, kodwa uluntu lwehlabathi lwe-Urological Thothology (i-Iup) ngoku yamkelwa rhoqo. Inkqubo yokuhlela iSuping ithatha umntu odumileyo we-nucleolar kunye nokungahambelani kwenyukliya. Amabakala aphezulu abonisa amathumba amaninzi kwaye adityaniswa ne-Pregnosis ehlwempuzekileyo. I-Isup yebakala leBanga le-1 le-iyunifoni ene-nuclei nge-nucleleli engekhoyo okanye engekhoyo inyukri. IBAKALA 2 ISIQINISEKISO SE-NUCEI YENKULUMBUZO NGE-NYANELO ENGCONO. Ibanga lesi-3 elikhulu, elingaqhelekanga le-Nuclei nge-nencleoli ebalaseleyo. Ibanga lesi-4 aliqhelekanga, i-nuclei ye-nuzari enemilo yebhihari okanye umahluko we-sarcomatoid. Ukubeka i-carcinoma yeseli ye-renali: Inkqubo ye-TNM ye-RCC ichaza ubungakanani bomhlaza, kubandakanya ubungakanani be-tumor eyintloko (t), ukubandakanyeka kweendawo ze-lymph zendawo (n). Inkqubo ye-TNM Sygram yeyona nkqubo isetyenziswayo yokusetyenziswa kwe-RCC. Isitayile esichanekileyo sibalulekile ekuzimiseleni izigqibo ze-prognosis kunye neendlela ezithile ze-T, n, kunye nee-M, kwaye zineenkcukacha ze-tumas, kunye nobukho be-memph kwii-mines okanye iindawo ezikude. Iingcali ze-phathologics zisebenzisa iziphumo ze-microscopic kunye neziphumo zokucinga ukuba zinike indawo efanelekileyo ye-TNM.immunonOhistochemists kwi-renal carcinoma patologmiststommumpemistommumists Iseli ye-renalin carcinoma pathology. Kubandakanya ukusebenzisa ii-antibodies ukufumanisa iiproteni ezithile kwiisampulu zezicubu. OKUNYE APHAKAMIBILI NGOKUGQIBELA UKUTHENGA phakathi kwe-RCC subsuttypet, eqinisekisa ukuxilongwa, kunye nokuchonga iithagethi zonyango ezinokubakho. Amagosa aqhelekileyo eHC asetyenziswa kwi-RCC iquka: I-Pax8: Isiphawuli esihlala sivakaliswa kwi-carnal sel carcinomas, ngakumbi iiseli ezicacileyo zeseli. ICais: ichazwe rhoqo kwiseli ecacileyo yeseli yeseli. I-CK7: Inceda ukwahlula phakathi kwe-RCC ye-RCC eyahlukeneyo, ihlala inesibindi ne-chromophobe rcc. I-Vilostin: zihlala zilungile kwi-Sarcomatoid RCC. I-CD117 (C-kit): ingaba luncedo ekuchongeni i-chromophobe i-chcrophobe i-chcc.pathology: Ingxelo ephambili ye-IntheTheThe ye-IntheTheThe ye-IntheThelthe ishwankathela iziphumo zoviwo lwe-pathological. Ibandakanya ezi zinto zilandelayo: Ulwazi lwesigulana kunye neenkcukacha ezichaziweyo. Inkcazo epheleleyo ye-tumoor. Inkcazo yemicroscopic yeeseli ze-tumor kunye noyilo. I-RCC ye-RCC. Ibakala le-Imp. Inqanaba le-TNM. Iziphumo zeShunohistochemication. Isimo seMargins (nokuba iiseli zomhlaza zikhona kwimiphetho ye-tishu esusiweyo). Izimvo zikagqirha ze-patologist kunye nesishwankathelo IZiko loPhando lweShandong Baeo Dlala indima ebalulekileyo ekuqhubeni ukuqonda kwethu kunye nonyango lomhlaza, kubandakanya Iseli ye-renalin carcinoma. Ngokwenza uphando kunye novavanyo lweklinikhi, la maziko afaka igalelo kuphuhliso lwezixhobo ezintsha zokuxilonga kunye nonyango, ekugqibeleni ukuphucula iziphumo zesigulana.concuensegeIseli ye-renalin carcinoma pathology yintsimi enzima ebandakanya uviwo ngononophelo kunye nohlalutyo lwezicubu zezintso. Ukuqonda amatyholo ohlukeneyo, iinkqubo zokuhlela, ukubeka isitali, kunye nendima ye-uRununohistochemistry kubalulekile ukuze zixilongwe ngokuchanekileyo, progunosis, kunye nocwangciso lonyango. Intsebenziswano phakathi kwama-Nathologists, oochwephesha boochwephesha bezempilo kubalulekile ekuboneleleni ngononophelo olufanelekileyo kwizigulana ezine-RCC.Iphepha elichazayo: Olu lwazi kukolwazi ngokubanzi kunye neenjongo zolwazi kuphela, kwaye azisebenzi kakuhle. Kubalulekile ukuba ujongene nengcali yezempilo efanelekileyo kuyo nayiphi na inkxalabo yezempilo okanye ngaphambi kokwenza naziphi na izigqibo ezinxulumene nempilo yakho okanye unyango.Izalathiso: Umbutho woMhlaza waseMelika Isiseko seSizwe seZintso