Unyango lwe-carnali ye-recinoma

Unyango lwe-carnali ye-recinoma . Ukhetho lwe unyango Kuxhomekeke kwizinto ezinje ngenqanaba lomhlaza, impilo yesigulana iyonke, kunye nokhetho. Ukufunyanwa kwangoko kunye nokungenelela kwangexesha kubaluleke kakhulu ekuphuculeni iziphumo.Indise i-renal carcinomaIseli ye-renalin carcinoma (I-RCC) lolona hlobo luqhelekileyo lomhlaza wabaninzi kubantu abadala. Ivela kwi-tube ityhubhu ye-proximal, inxenye yezintso ezicoca igazi kwaye isusa iimveliso zenkunkuma. Ngelixa eyona nto ibalulekileyo kwi-RCC ayisoloko icacile, izinto ezithile zomngcipheko zinxulunyaniswa nokuphuhlisa esi sifo. Ezi zinto zinobungozi zibandakanya ukutshaya, ukukhuluphala, uxinzelelo lwegazi oluphezulu, kunye neemeko zemvelo ezinje nge-von hindal-lindau (VHL) yesifo. Kwi IZiko loPhando lweShandong Baeo, Sizimisele ukubonelela ngolwazi olubanzi kwaye siqhubekile unyango Iinketho zabaguli be-RCC.types ze-carcomomah iselfowuni ye-RCCE zininzi ze-RCC, nganye ineempawu ezahlukeneyo kunye neempawu ezinokubakho kuzo unyango. Olona phawu luqhelekileyo lubandakanya: Cima i-RCC ye-RCC: Olu lolona hlobo lube luxhaphakileyo, i-accounting malunga ne-70-80% yamatyala. I-Papillary Rcc: Okwesibini uhlobo oluqhelekileyo, olumele malunga ne-10-15% yamatyala. I-chromophobe rcc: Uhlobo oluncinci oluqhelekileyo, lwenza malunga ne-5% yamatyala. Ukuqokelela i-DUCC RCC: Ifom enqabileyo nenobundlongondlongo ye-rcc.ct unyango Indlela ye-RCC ixhomekeke kwizinto ezininzi, kubandakanya nenqanaba lomhlaza, impilo yesigulana, kunye ne-RCC. Eqhelekileyo unyango Uhlengahlengiso lubandakanya utyando, unyango olujolisiyo, umongo wokunyanga, kunye ne-radiation i-quindorgergergergergerger.ingacals ihlala iphambili Unyango lwe-carnali ye-recinoma, ngakumbi xa umhlaza usekwele ndlu. Ukhetho loqhaqho lubandakanya: I-Nephrectomy ye-raid Oku kubandakanya ukususwa ngokupheleleyo kwezintso ezichaphazelekayo, kunye nezicubu ezijikelezileyo ezinje nge-adrenal gland kunye ne-lymph node. Inxalenye ye-Nephrectomy: Oku kubandakanya ukususa kuphela ithumba kunye nomda omncinci wezicubu zempilo, ukugcina uninzi lwezintso kangangoko kunokwenzeka. Le ndlela idla ngokukhethwa amathumba amancinci okanye xa isigulana sinezinzwane enye kuphela. Ezi ntlalo zinokusebenza ngokukodwa kwi-RCC. Unyango oluqhelekileyo oluqhelekileyo lubandakanya: I-vegf inhibitors: La machiza athintela i-vascir endothelial endoteral yokukhula (i-vegf), ebaluleke ngokokubekwa kwemithambo yegazi entsha ebonelela amathumba. Imizekelo ibandakanya i-sunritinib (Sutent), i-sorafenib (i-nexavar), i-pazopanib (i-votlie), i-axitinib (i-inlyta), kunye neCabhozantinib (Cabhometyx). I-MTRous inhibitors: La machiza athintela ithagethi yaseMammalian yeParamycin (Mtor) yendlela, elawula ukukhula kweseto kunye neMetabolism. Imizekelo ibandakanya iTemissimos (iTeririliyo) kunye ne-Everolimus (i-aphinetor) .immunopokimmunopyungopy uhombisa amandla amajoni omzimba omzimba ukuze alwe nomhlaza. IZiyobisi zokuPhuti ze-RCE ye-RCC ibandakanya: Indawo yokujonga amagorha yokutshekisha: La machiza athintela iiproteni ezithintela amajoni omzimba akwazi ukuhlasela uhlambulisi womhlaza. Imizekelo iquka i-nivoolini (Opdivo), i-Pembromizumab (i-Iplimudab), Iplimundab (Yervoy), kwaye i-tebizolizmab (ye-teeceriq). UNivoLUmab uhlala edityaniswe ne-IPilindab kwisifo esikhawulezayo. I-cytokines: I-Deseuki ephezulu yeDomeukin-2 (il-2) kunye ne-inverferon-Alfa (i-Il-α-α) i-cytokenes inokukhuthaza amajoni omzimba. Nangona kunjalo, la machiza anokuba neziphumo ebezingalindelekanga kwaye asetyenziswa kancinci ngoku ngenxa yokufumaneka kwe-Newderrapies I-Interradies yaseNewRotheradies. Ayisiyo iprayimari Unyango lwe-carnali ye-recinoma, kodwa inokusetyenziselwa ukuphatha iintlungu okanye ezinye iimpawu ezibangelwa ngumhlaza ophambili oye wasasaza amanye amalungu omzimba. Ngamanye amaxesha isetyenziswa emva kotyando ukuba kukho umngcipheko ukuba umhlaza uza kubuya okanye ukuba ezinye zethumba azinakususwa. I-Sterereotactic yonyango lwe-radialic ye-radiation (i-SBRT) ihambisa iidosi eziphezulu zemitha kwaye ngamanye amaxesha zisetyenziselwa i-Carcinoma ye-Carcnoma kunye nenqanaba le-RCCE ye-RCCY lelokho unyango indlela. Inqanaba lisekwe kubungakanani kunye nendawo ye-tumar, nokuba isasazeke kwiindawo ezikufuphi, kwaye nokuba i-turigas i-tercin i-tumr ye-surkoathe tumar ivalelwe kwizintso kwaye incinci ubukhulu. Unyango Ngokwesiqhelo kubandakanya ukususwa kwe-sumor, nokuba yeyokuthintela okanye i-nephrectomy ye-II Renal I-TurCINOAL TUMOR inkulu kunezintso. Unyango Ihlala ibandakanya i-biefrectomy ye-biefcialy.stage III I-I-I-I-CarCINAL CARCINAAL I-Tumor isasazeke kwiindawo ezikufutshane ze-lymph okanye ikhule imithambo enkulu okanye izicubu ezingqongileyo. Unyango Inokubandakanya iNephrectomy ye-phyph, i-lymph node, kwaye inokwenzeka i-Adrause unyango (i-E.G. Unyango Ukhetho lunokubandakanya utyando ukuze ususe i-tumor eyintloko (i-cytoredpectictop), i-ranotherapy ejolise kuyo, i-tunotherapy, i-radiation yonyango, okanye indibaniselwano yezi ndlela. Uvavanyo lweklinikhi lusenokukukhetha.Live nge-Calnal Calculalive nge-RCC ye-RCC inokunika imiceli mngeni eyahlukeneyo, ngokwasemzimbeni nangokweemvakalelo. Kubalulekile ukuba nenkqubo yenkxaso eyomeleleyo kunye nokufikelela kunyango olubanzi. Izigulana zinokufumana iziphumo ebezingalindelekanga unyango, njengokudinwa, isicaphucaphu, urhudo kunye nolusu. Ukulawula ezi ziphumo zecala liyinxalenye ebalulekileyo yononophelo lomhlaza. Ukongeza, ukugcina indlela yokuphila esempilweni, kubandakanya ukutya okulinganayo kunye nokuzilolonga rhoqo, kunokunceda ukuphucula impilo-ntle. KwiZiko lePhandong baookA ye-Bharator IZiko, iqela lethu elizinikeleyo libonelela ngononophelo kwaye lisebenze unyango Izicwangciso zokunceda abaguli balawule i-RCC yabo kwaye baphucule umgangatho wabo wobomi. Sikwindawo ye-jinan entsha, kunye nemishini yethu ye-chinalines kunye 'eyenziwe kwi-china 2025' yesicwangciso-nkqubo. unyango ihlala ivela, kunye nonyango olutsha kunye neendlela zokuphuhliswa. Inkqubela phambili yakutshanje ibandakanya: Indibaniselwano amaJunOtherapy: Ukudibanisa amachiza amasiko ngokuhlukeneyo, anjengeNivolomab noIplimeyab, kubonisile iziphumo eziphuculweyo kwezinye izigulana ezine-RCC. Ukuphuculwa konyango olujolisiweyo: Izizukulwana ezintsha zonyango olujolisiweyo zenziwa ngokuphuculwa ngokuphuculweyo kunye neziphumo ezimbalwa. IIMALI YOKUGQIBELA: Abaphandi basebenzela ukuchonga i-biomarks enokunceda ekuqinisekiseni ukuba zeziphi izigulana ezinokwenzeka ukuba ziphendule ngqo unyangoI-S.Prognosis ye-CarCoathe iDarcnomis ye-RCCNosis ye-RCCU iyahluka ngokuxhomekeke kwinqanaba lomhlaza, impilo yesigulana iyonke, kunye nempendulo kuyo unyango. Ukufunyanwa kwangoko kunye nokungenelela kwangexesha kubaluleke kakhulu ekuphuculeni iziphumo. Izigulana ezine-RCC ye-RCC efakwe kwi-RCC enotyando zinethuba eliphezulu lokunyangwa. Nangona kunjalo, iproginologus ayithandeki kwizigulana ezine-RCC. Uphando oluqhubekayo lujolise ekuphuhliseni okutsha kunye nokusebenza ngakumbi unyangos ukuphucula i-prograsis kwiprogramu yazo zonke izigulana ezine-RCC.CLInical Iimvavanyo zemvavanyo zezifundo ezivavanyayo ezivavanyayo unyangoS okanye kwiindlela ze-RCC. Ukuthatha inxaxheba kwityala leklinikhi kunokubonelela ngokufikelela kwiindlela zokucheba ezinqamlezileyo ezingekafumaneki ngokubanzi. Izigulana zinomdla wokufunda ngakumbi malunga nezilingo zeklinikhi kufuneka zithethe nogqirha. Umthombo: Umhlala-phantsi waseMelika (www.cancerr.org)