Unyango olutsha lwe-prostal yomhlaza womhlaza

Imitha yolwelo, ekwabizwa ngokuba yi-radiaphacemacermical prapy, ivela njengethembisayo unyango Inketho yokuqhubela phambili Umhlaza womhlaza. Le ndlela yokucwangciswa kwenkqubo ihambisa i-radiation ejolise ngqo kwiiseli zomhlaza kuwo wonke umzimba, ukuhambisa izibonelelo ezinokubakho kwimitha yangaphandle yebhunga. Unyango lusebenzisa isotopes radiopes eqhotyoshelwe kwiimolekyuli ezizimeleyo Umhlaza womhlaza Iiseli, ukunciphisa umonakalo kwizicubu ezinempilo.Intoni Imitha yolwelo Unyango lwe Umhlaza womhlaza?Imitha yolwelo Unyango, ukwabizwa ngokuba nguRadiaphacemastical Prepy okanye iMida yenkqubo yenkqubo, isebenzisa amachiza ama-radid elawulwayo. La machiza ajikeleza kuwo wonke umzimba kwaye ukhethe iiseli zomhlaza, ukuhambisa i-radiation ngqo kubo. Le ndlela inikezela ngendlela yokufikelela kwiiseli zomhlaza ezinokuthi zisasaze ngaphaya kwe-prostate gland, ezenza ukuba zibekho unyango kwi-metastatic Umhlaza womhlaza. Kwi IZiko loPhando lweShandong Baeo, siqhubeka nokwenza uphando kunye nokucoca ukusetyenziswa kweendlela ezinjalo ezikhoyo.Iyasebenza? Le nkqubo ibandakanya ukunamathela kwi-istoe ye-radiope ukuya kwimotoule ejolise kuyo. Le molekyuli ifuna kwaye ibophelele kwiiproteni ezithile okanye ii-receptors ezifunyenwe Umhlaza womhlaza iiseli. Nje ukuba ichiza lilawulwa, lihambahamba kwigazi, lifumana iiseli zomhlaza, kwaye ihambisa idosi yendawo yemitha, itshabalalisa iiseli zomhlaza ngelixa incipha i-tishus ejikelezileyo. Cinga ngayo njengendawo yokujonga i-Shopsing kuphela utshaba kuphela.wa Umhlaza womhlaza Izigulana zinokuxhamla Imitha yolwelo?Imitha yolwelo ngokuyintloko isetyenziswa kwizigulana ezihamba phambili Umhlaza womhlaza Oko kusasazeke kwamanye amalungu omzimba (i-metastatitic Umhlaza womhlaza), ngakumbi xa enye unyango Izinketho ezinje ngonyango lwehomoni kunye ne-chemotherapy azisasebenzi. Ihlala iqwalaselwa kwizigulana ezivuza iithagethi ezithile, ezinje nge-PSMA Unyango lwemitha ezingamanzi kuba Umhlaza womhlazaIqela imitha yolwelo Unyango luyafumaneka okanye luphantsi kophuhliso lokunyanga Umhlaza womhlaza. Nazi ezinye zezinto ezibalaseleyo: I-Luttium-177 psma Pepylutetium-177 Psma (177Lu-psma-psma) yenye yezona zisetyenziswa kakhulu kwaye zifundwa Unyango lwemitha ezingamanzi kuba Umhlaza womhlaza. I-PSMA yiprotheyini efunyenwe kugxininiso oluphezulu kumphezulu omkhulu Umhlaza womhlaza iiseli. I-177Lu-psma iqulathe isotope ye-radiope lutetium-177 iqhotyoshelwe kwimolekyuli ebopha kwi-PSMA. Oku kuvumela i-radiation iza kusiwa ngokuthe ngqo kwiiseli zomhlaza zibonisa i-psma. Izifundo zibonakalise izibonelelo ezibalulekileyo malunga nokusinda kunye nobuncinci bobomi bezigulana eziphathwe nge-177Lu-psma emva kokuba ezinye iindlela zisilele. KwiZiko lePhandong Bhasoong BaeoR IZiko, uphando lwethu lujolise ekuphuculeni ukusebenza kunye nokunciphisa iziphumo ebezingalindelekanga zale radium. Unyango lwe-radiation yeradi isetyenziselwe i-metastatic Umhlaza womhlaza Oko kusasazeke emathanjeni kodwa hayi kwamanye amalungu. I-radium-223 I-calcium ye-calcium kwaye ithathiwe ngokukhethekileyo ithambo, ngakumbi kwiindawo apho umhlaza wonakalise ithambo. I-radiation ikhutshwe yi-radium-223 itshabalalisa iiseli zomhlaza kwithambo, incedisa ekupheliseni iintlungu kwaye iphucule ukusinda.benet ye Imitha yolwelo kuba Umhlaza womhlazaImitha yolwelo inikezela izibonelelo ezinokubakho ngaphezulu kwemveli unyango Iindlela: Unyango olujolise kulo: Kukhethwe kujolise kwiiseli zohlaza, ukunciphisa umonakalo kwizicubu ezisempilweni. Inkqubo yenkqubo: Unokufikelela kwiiseli zomhlaza ezisasazeke kuwo wonke umzimba. Umgangatho ophuculweyo wobomi: Banokunciphisa iimpawu kwaye baphucule umgangatho wobomi bonke abaguli abahamba phambili Umhlaza womhlaza. Inokubakho ukusinda ixesha elide: Izifundo zibonakalisile oko imitha yolwelo Ungandisindisa kwizigulana ezithile.Iziphumo zexesha elide Unyango lwe-radiation yeradiNjengawo wonke umhlaza unyango, imitha yolwelo inokubangela iziphumo ebezingalindelekanga. Iziphumo ezichaziweyo zecala zixhomekeke kuhlobo lwesiyobisi esinerediyo esisetyenzisiweyo kunye nesigulana somntu ngamnye. Iziphumo ebezingalindelekanga eziqhelekileyo zibandakanya i-suusea ye-suusea yethambo (ekhokelela kwiiseli eziphantsi) zezandla ezizomileyo ziya kukubeka esweni iziphumo ebezingalindelekanga kwaye zinikezele ngononophelo. Yintoni onokuyilindela ngexesha Unyango lwe-radiation yeradiI unyango Inkqubo iqhele ukubandakanya: Ukubonisana kokuqala kunye nogqirha wakho we-oncologist ukufumanisa ukuba imitha yolwelo kufanelekile kuwe. Ukucingisisa ukuvavanya ubungakanani bomhlaza wakho kwaye ubone ukuba ichaza ilungelo lokujolisa kwichiza lerediyo. Ulawulo lweziyobisi ze-radioung ngokungathandabuzekiyo. Ukuqeshwa rhoqo ukubeka iliso kwimpendulo yakho unyango kwaye ulawule nayiphi na imiphumo ebezingalindelekanga.Ikamva le Imitha yolwelo ngaphakathi Unyango lomhlazaIntsimi ye imitha yolwelo kuba Umhlaza womhlaza ivele ngokukhawuleza. Abaphandi baphuhlisa amachiza amatsha erediyo ejolise kwiimolekyuli ezahlukeneyo kwiiseli zomhlaza, kunye nezicwangciso zokudibanisa imitha yolwelo kunye nezinye unyango, njengokuhlwa kunye nonyango lwehomoni. Injongo kukuphucula ngakumbi ukusebenza unyango kunye nokusinda kwizigulana ezihamba phambili Umhlaza womhlaza. Siyakumema ukuba uqhagamshele ukuze uqhagamshelane ne-Shandong Baeong Badrar Institute iZiko lokufunda ngakumbi malunga negalelo lethu kule ntsimi inomdla.Ukusasazeka okwahlukileyo Unyango lwemitha ezingamanziUthelekiso olulula lwezi zinto zimbini ziphambili Unyango lwemitha ezingamanzi ifumaneka Umhlaza womhlaza: Ithagethi yonyango Sebenzisa iziphumo ebezingalindelekanga ze-Lutettium-177 I-PSMA (177U-177Lu-PSMA-PSMA) I-PSMA (i-PROstate-Antign) Umhlaza womhlaza . Umhlaza womhlaza ukuya kwi-bone nausea, ukugabha, Intlungu yethambo, uxinzelelo olukhulu lwethambo Iphepha elichazayo: Le theyibhile ibonelela ngamagqabantshintshi olwenziwe lula kwaye akufuneki isetyenziswe njengendawo yokuhlala icebiso lonyango. Nxibelelana nomnikezeli wakho wezempilo ukuze ufumane isikhokelo.I Imitha yolwelo Ilungelo lakho? Ukuba ukuqhubela phambili Umhlaza womhlaza kwaye unomdla wokufunda ngakumbi malunga imitha yolwelo, Thetha nogqirha wakho we-oncologist. Banokuvavanya imeko yakho kwaye babone ukuba le unyango Inketho ilungele wena.Izalathiso:[1] IZiko leSizwe leSizwe. https: //www.cancer.gov/