kathathu umhlaza wamabele

Umhlaza othi gca ongezantsi: Isikhokelo esibanzi somhlaza ongezantsi webele: Umhlaza we-CNBC ongenasigulana ongesosimo somhlaza webele ongaveza ii-receptor, iprogesterone, okanye i-progesterone. Oku kunganqongopheli kwesazela kwenza ukuba kube nzima ngakumbi kwaye kube nzima ukunyanga xa kuthelekiswa nakwamanye amatyholo omhlaza wamabele. Esi sikhokelo sinika isishwankathelo esibanzi se kathathu umhlaza wamabele, egubungela iimpawu zayo, isifo, iindlela zonyango, kunye nezixhobo zenkxaso. Sijonge ukukuxhobisa ngolwazi kunye nokuqonda ukuhamba olu hambo lucelomngeni.

Ukuqonda iimpawu ze-TNBC

Yintoni eyenza i-TNBC yahlukile?

Ngokungafaniyo nezinye iintlobo zomhlaza zebele, kathathu umhlaza wamabele Ukunqongophala kwe-estrogen Ezi ndawo zikhutshelwa kuzo zihlala zijolise kunyango lwabahlobo abanomhlaza, kodwa ukungabikho kwabo kwi-TNBC kwimida yonyango. Oku kuhlala kukhokelela kwizifundo ezinobundlongondlongo kunye nomngcipheko ophezulu wokuphinda uqalise kwakhona.

Ukuxhaphaka kunye nezinto zomngcipheko

Kathathu umhlaza wamabele i-akhawunti emalunga ne-10 ukuya kwi-20% yabo bonke umhlaza webele. Izinto zomngcipheko ezinxulunyaniswa ne-TNBC zibandakanya iminyaka yobudala ekuxilongeni, i-geca1 ye-gencho1, ubuhlanga base-Afrika wase-Afrika, kunye nembali yosapho yomhlaza webele. Nangona kunjalo, uninzi lwabafazi kufunyaniswe nge-TNBC abanakho izinto ezibonakalayo zomngcipheko.

Uxilongo kunye nokuzibeka kwe-TNBC

Inkqubo yokuqonda isifo

Ukuchonga kathathu umhlaza wamabele Ngokwesiqhelo kubandakanya i-biopsy yokuhlola iiseli zethumba phantsi kwemakroskopu. Uvavanyo lwe-Shounohistochemical Stailing (IHC) lufumanisa ubukho okanye ukungabikho kwe-ER, PR, kunye neendawo zayo. Olunye uvavanyo, njengokucinga ingcinga (i-mammography, i-ultragraphind, i-MRI), inokusetyenziselwa ukuvavanya ubungakanani bomhlaza.

Isitayile kunye nePrognosis

Isitayile simisela ubungakanani kunye nobungakanani bomhlaza, ukuchaphazela izigqibo zonyango kunye neprosissis. Inkqubo ye-TNM isetyenziswa, ivavanya ubungakanani be-tumor (T), ukubandakanyeka kwe-lymph node (n), kunye ne-metastasis ekude (m). Prognosis kwi-TNBC iyahluka ngokuxhomekeke kwinqanaba kunye nezinye izinto; Ukufunyanwa kwangoko kunye nokunyanga ngexesha elifanelekileyo kubalulekile ukuze kuphuculwe iziphumo.

Izinketho zoNyango lwe-TNBC

Utyando

Utyando luhlala lungumgca wokuqala wonyango kathathu umhlaza wamabele, ejolise ekususeni ithumba elinomhlaza. Oku kunokubandakanya i-LUMPECTOMY (isusa ithumba) okanye i-mastectomy (isusa ibele). I-Sintinel Lymph Node biopsy okanye i-Axillary lymph node dismymess inokwenziwa ukuvavanya ukubandakanyeka kwe-lymph node.

Chemotherapy

Chemotherapy is a cornerstone of TNBC treatment, often used before surgery (neoadjuvant chemotherapy) to shrink the tumor or after surgery (adjuvant chemotherapy) to reduce the risk of recurrence. Iirejimeni ezahlukeneyo ze-chemotherapy ziyafumaneka, zikhethwe ngokusekelwe kwizinto ezizodwa. Uphando Iyaqhubeka nokuhlola i-commotheraperapy ye-ivel chemotheration yokuphucula ukusebenza kakuhle.

Unyango lwe-radiation

Unyango lwe-radiation lonyango lusebenzisa imitha yamandla amakhulu ukubulala iiseli zomhlaza. Ihlala isetyenziswa emva kotyando ukutshabalalisa naziphi na iiseli zomhlaza oshiyekileyo esifubeni okanye ezikufuphi ne-lymph. Ingasetyenziselwa ukuphatha isifo se-metastatic.

Unyango olujolisiweyo kunye nemmunotherapy

Ngelixa i-TNBC ayiphenduli kunyango lwehomoni okanye unyango olujolise kuye, uphando luyaqhubeka kwiindlela ezijolise kuzo kunye nomonotherapies. Ezinye iindlela ekugxilwe kuzo zigxile kwiindlela ezithile ezichaphazelekayo ekukhuleni kwe-TNBC, ngelixa i-gonoOtherapies ijolise ekukhuliseni amajoni omzimba ukuze alwe nomhlaza. Olu nyango lubonisa isithembiso kodwa lisephantsi kophando.

Ukuhlala kunye ne-TNBC

Unonophelo lokulandela

Ukuqeshwa rhoqo kubalulekile emva kokuba unyango lubeke esweni ukuphinda iphinde iphinde iphinde iphinde iqalise. Oku kuqeshwa ngokwesiqhelo kubandakanya iimviwo zomzimba, ukucinga ukuvavanya, kunye novavanyo lwegazi. Ukufunyanwa kwangoko kokuphinda kuchazwe kubalulekile kulawulo olusebenzayo.

Inkxaso kunye nezixhobo

Ukujamelana nesifo kathathu umhlaza wamabele kunokuba ngumceli mngeni. Inkxaso evela kusapho, izihlobo, kunye namaqela enkxaso kubalulekile. Imibutho emininzi inikezela ngezixhobo kunye nenkxaso kubantu abachaphazeleka yi-TNBC. Cinga ngoQhakamshelwano IZiko loPhando lweShandong Baeo ngolwazi olongezelelekileyo kunye nezixhobo. Banika ukhathalelo olubanzi lomhlaza, kubandakanya nobungcali ekunyangeni izinto ezahlukeneyo zomhlaza.

Uphando olungaphezulu kunye novavanyo lweklinikhi

Uphando kathathu umhlaza wamabele ihlala ivela, kunye nezilingo eziqhubekayo zeklinikhi ziphonononge iindlela ezintsha zonyango kunye nokuphucula iziphumo. Ugqirha wakho we-oncologist unokuxoxa ngenzondelelo unokuthatha inxaxheba kwizilingo zekliniki ezinokuthi zilungele imeko yakho ethile. Ukuhlala unolwazi malunga nenkqubela phambili yophando kwi-TNBC ibalulekile.