Ukwelashwa komdlavuza we-4th esiteji samaphaphu

Isigaba 4 Umdlavuza wamaphaphu, owaziwa nangokuthi umdlavuza wamaphaphu we-metastatic, kusho ukuthi umdlavuza usakazekele kwezinye izingxenye zomzimba. Ngenkathi kungukuxilongwa okukhulu, intuthuko ekwelashweni inikeza ithemba lokuphatha lesi sifo kanye nokwenza ngcono impilo. Izinketho zokwelashwa zivame ukufaka i-chemotherapy, ukwelashwa okuhlosiwe, i-immunotherapy, ukwelashwa kwemisebe kanye nokunakekelwa kokudla. Indlela ethile incike ezintweni ezahlukahlukene, kufaka phakathi uhlobo lomdlavuza wamaphaphu, ukuguqulwa kwalo fuzo, kanye nempilo yomuntu ngamunye. Ukuqonda lezi zinketho futhi usebenza ngokubambisana nethimba lezokwelapha kubalulekile ngokwenza izinqumo ezinolwazi futhi uzulazule uhambo lokuvutha ama-turnerstage, okusho ukuthi umdlavuza wamaphaphu uzwakalise ukuthi umdlavuza wamaphaphu uzwakalise ukuthi ubuchopho obude njengengqondo. Lokhu kusabalala kwenzeka lapho amaseli omdlavuza ehlukana nesimila esiyinhloko futhi ahambe ngegazi noma uhlelo lwe-lymphatic kwezinye izingxenye zomzimba we-carcer, izinhlobo ezimbili eziphambili zomdlavuza wamaphaphu: Umdlavuza we-cell ongelona omncane (NSCLC): Lolu uhlobo oluvame kakhulu, accounting cishe ama-80-85% wamacala omdlavuza wamaphaphu. Ama-subtypes we-NSCLC afaka i-adenocarcinoma, squamous cell carcinoma, kanye ne-carcinoma enkulu ye-carcinoma enkulu. Umdlavuza omncane weseli (i-SCLC): Lolu hlobo aluvamile kodwa luvame ukukhula futhi lusakaze ngokushesha ukwedlula i-NSCLC.Diagnosis kanye ne-stachdiagnosis ngokuvamile kubandakanya izivivinyo zokucabanga (ama-st scans, ama-biopsies, nezinye izinqubo. Isitayela sinquma ubukhulu bokusakazeka komdlavuza. Isigaba 4 yizindlela zokuhlanza ezisezingeni eliphakeme kakhulu ze- Ukwelashwa komdlavuza we-4th esiteji samaphaphuNgenkathi ikhambi kungenzeka lingakwazi Ukwelashwa komdlavuza we-4th esiteji samaphaphu, ophathweni bahlose ukulawula umdlavuza, badambise izimpawu, futhi bathuthukise ikhwalithi yempilo. Uhlelo oluthile lokwelashwa luncike ezicini eziningana, kufaka phakathi uhlobo lomdlavuza wamaphaphu, ukuguqulwa kwezakhi zofuzo, lapho umdlavuza usakaze khona, futhi impilo yesiguli iphelele isebenzisa izidakamizwa ukubulala umdlavuza. Imvamisa isetshenziswa njengokwelashwa komugqa wokuqala Ukwelashwa komdlavuza we-4th esiteji samaphaphu, ikakhulukazi nge-SCLC kanye nezinhlobo ezithile ze-NSCLC. Ingahanjiswa nge-intravenously (ngokusebenzisa umthambo) noma ngomlomo (njengamaphilisi) izidakamizwa zokwelapha ezihlanganisiwe. Lezi zindlela zokwelapha zivame ukusetshenziselwa i-NSCLC ngokuguqulwa okuthile kwezakhi zofuzo. Amatshe ajwayelekile afaka i-EGFR, Alk, Ros1, ne-BRAF. Ukuhlola lokhu kuguqulwa kubalulekile ngaphambi kokuqala ukwelashwa.Immunotherapyimmunotherapy kusiza amasosha omzimba alwe nomdlavuza. Ukuvimbela ama-incuneice point, njenge-pembrolikumab (Keytruda), i-nivolumab (Opdivo), i-atezolikumab (Tecentriq), kanye neDurvalumab (IMFINZI), zivame ukusetshenziswa ngaphakathi Ukwelashwa komdlavuza we-4th esiteji samaphaphu. Le mishanguzo ivimba amaprotheni avimbela amaseli omzimba ekuhlaseleni amaseli omdlavuza wamaseli we-carncer cell.radiation asebenzisa imisebe ephezulu kakhulu ukubulala umdlavuza. Ingasetshenziswa ukuncipha kwamathumbu, ukudambisa izinhlungu, noma ukuphatha umdlavuza osatshalaliswe ebuchosheni noma ekunakekelweni kwe-taboaliative ye-bones.palliative Carepalliative kugxile ekunciphiseni izimpawu kanye nokwenza ngcono impilo. Kungafaka ukuphathwa kobuhlungu, ukusekelwa kokudla okunempilo, nokusekelwa okungokomzwelo. Ukunakekelwa kwePalliative kungenziwa eceleni kwezinye izindlela zokwelapha.Specific ukwelashwa okususelwa ekuthandweni komdlavuza wamaphaphu we-Stage 4 NSCLCREDEMENT STRETE STRECTIes ye-Stage 4 NSCLC kuncike kwi-subtype ethile (i-adenocarcinoma, squamous cell carcinoma, njll.) Futhi ukuba khona kwezakhi zofuzo. Izindlela ezijwayelekile zifaka: I-Adenocarcinoma nge-EGFR ukuguqulwa kwe-EGFR: I-EGFR Inhibitors (E.G., OSTERTINIBIB, GEFITINIB, ERLOTINIBIB) I-AdenocarciNoma nge-ALK RESERELANTEEN: I-Alk inhibitors (e.g., Alectinib, Crizotinib, Brigatinib) I-Adenocarcinoma nge-ros1 reyerment: I-ROS1 inhibitors (E.G., Entrectonib, Crizotinib) I-NSCLC ngenkulumo ye-PD-L1: I-ImmunoSatherapy (E.G., Pembrolikumab, Atezolikumab) I-Chemotherapy: Imvamisa kuhlangene ne-Im-i-Im-i-Im-I-Therapy.Retement eqondiwe ye-Stage 4 SCLCRETETENT ye-Stage 4 SCLC imvamisa ifaka ama-chemotherapy futhi, kwezinye izikhathi, ama-immunotherapy. I-Chemotherapy: AmaRegimens asetshenziswa kaningi afaka i-Cisplatin noma i-carboplatin ehlanganiswe ne-etoposide. I-ImmunoSatherapy: I-atezolikumab noma i-durvalumab ingangezwa ku-chemotherapy. Ukwelashwa kwemisebe: Ingahle isetshenziselwe ukwelapha ama-tums esifubeni noma ubuchopho.Nganisa uhambo lokwelashwa noShandong Bandong BAOFA Ucwaningo lwe-Institutechoosing a Ukwelashwa komdlavuza we-4th esiteji samaphaphu kubalulekile. I-Shandong Baafa Cancer Research Institute Inikeza ukunakekelwa okuphelele, kufaka phakathi ukuxilongwa okuthuthukile, amasu okwenziwa owenziwe ngezifiso, kanye nezinsizakalo zokusekela. Iqembu lethu le-Oncologists, abelaphi bemisebe, kanye nochwepheshe bezokunakekela abasekelayo basebenzisana ukuhlinzeka ngemiphumela engcono kakhulu. Siyaqonda izinselelo iziguli ezibhekana nazo futhi zizibophezele ekuhlinzekeni ngokunakekela nokunakekelwa okusebenzayo kwezilingo ze-.clinical izilingo yizifundo zokucwaninga ezivivinya ukwelashwa okusha noma izindlela ezintsha zokusebenzisa ukwelashwa okusha. Iziguli ezine Ukwelashwa komdlavuza we-4th esiteji samaphaphu kungahle kucatshangelwe ukubamba iqhaza ezivivinyweni zemitholampilo ukufinyelela ekwelashweni kokusika. Udokotela wakho angakusiza ekuboneni ukuthi ngabe kucaca ngecala lomtholampilo kuwe.Qapha kanye ne-OutloolotterferI Ukwelashwa komdlavuza we-4th esiteji samaphaphu Iyahlukahluka ngokuya ngezinto ezifana nohlobo lomdlavuza wamaphaphu, ubukhulu bokusakazeka, ukuguqulwa kwezakhi zofuzo, kanye nempilo yesiguli yonke. Ngenkathi umdlavuza wamaphaphu 4 amaphaphu awelapheki ezigulini eziningi, ukwelashwa kungasiza ukulawula lesi sifo, kuthuthukiswe ikhwalithi yempilo, futhi kwandise ukusinda. Ucwaningo oluqhubekayo luholela ekwelashweni okusha nokwengeziwe. Amanani okusinda komdlavuza we-Stage 4 Lung (5-Nami) Uhlobo olulinganiselwa lweminyaka engu-5 Izinga le-NSCLC elizungeze i-10% ye-SCLC ezungeze i-2% * Amanani okusinda ngakunye ayahlukahluka ngokusekelwe ezintweni eziningi.Living neSigaba 4 umdlavuza womdlavuza we-Stage 4 Ukwelashwa komdlavuza we-4th esiteji samaphaphu kungaba yinselele, kepha kubalulekile ukugxila kwikhwalithi yempilo. Lokhu kufaka phakathi ukuphatha izimpawu, ukugcina impilo enempilo, nokufuna ukusekelwa okungokomzwelo. Cabanga ngalezi zici: Ukuphathwa kwezimpawu zokuphathwa kwezimpawu kubalulekile ekuthuthukiseni ikhwalithi yempilo. Lokhu kungafaka umuthi wobuhlungu, izidakamizwa ezilwa nenhliziyo, kanye nezinye izindlela zokwelapha ukubhekana nezimpawu ezithile.Niserrition kanye nokuzivocavoca umzimba okunempilo nokuzibandakanya ekuzivocavoca okujwayelekile (njengoba kubekezelelwe) kungasiza ukuthuthukisa amazinga wamandla kanye nenhlala-kahle. Thintana nomeluleki wokudla obhalisiwe noma ongokomzimba wezincomo ezenzelwe wena.Izincomo zokusekelwa kwe-.monational ubalulekile ekubhekaneni nezinselelo ezingokomzwelo zomdlavuza wamaphaphu. Lokhu kungafaka ukwelashwa, amaqembu okusekela, noma ukuxhumana nabanye abantu abanomdlavuza wamaphaphu.hope for the futuresearch kube ukwelashwa okusha nokuthuthukile kwe Ukwelashwa komdlavuza we-4th esiteji samaphaphu iyaqhubeka. Lezi zinto ezithuthukayo zinikeza ithemba lokunweba ukusinda kanye nokwenza ngcono impilo yabantu abaphila nalesi sifo. Ukusebenza ngokubambisana nethimba lakho lezokwelapha futhi uhlale unolwazi ngezinketho zakamuva zokwelashwa kungakunika amandla okwenza izinqumo ezinolwazi ngokunakekelwa kwakho.Ukuzikhulula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi alwenzi izeluleko zezokwelapha. Hlala uthintana nodokotela wakho noma omunye umhlinzeki wezempilo ofanelekayo wanoma yimiphi imibuzo ongaba nayo ngesimo sezokwelapha noma ukwelashwa.