Intuthuko ekwelashweni komdlavuza wamaphaphu

Ukwelashwa komdlavuza wamaphaphu kubonile inqubekela phambili emangalisayo eminyakeni yamuva. Lo mbhalo uhlola okwakamuva Intuthuko ekwelashweni komdlavuza wamaphaphu, ukumboza izindlela zokwelapha ezintsha njengokwelashwa okuhlosiwe, i-immunotherapy, namasu wokuhlasela kancane. Sithola imininingwane yalezi zindlela zokwelashwa, izinzuzo zabo, kanye nemiphumela emibi ebanzi yalabo abafuna umdlavuza wamaphaphu (izinhlobo ze-stagelung ze-cell ancrances (NSLC) kanye ne-cell cell acceract (SCLC). I-NSCLC uhlobo oluvame kakhulu, i-accounting cishe ama-80-85% awo wonke amacala omdlavuza wamaphaphu. Isigaba somdlavuza wamaphaphu siyisici esibucayi ekunqumeni isu elifanele lokwelashwa. Izitebhisi zisuselwa ngosayizi nendawo yendawo yesimila, noma ngabe isabalale kwizindawo ze-lymph, futhi uma ihlelwe nge-metastase ekwakhekeni kwezitho zomdlavuza we-orgrens.surgical e-lung cancer forkurkgery ihlala ithuluzi le-NSCLC esezingeni eliphakeme. -Bonakalayo Intuthuko ekwelashweni komdlavuza wamaphaphu Kwenziwe amasu okuhlinza, okunikeza iziguli izinketho ezingahlaseli futhi zithuthukisiwe imiphumela ethuthukisiwe: amasu okuhlinza ama-varotic kanye nokuhlinzwa kwamarobhothi yizindlela ezincane ezihlaselayo ezisebenzisa izinsimbi ezincane nezinsimbi ezikhethekile. Lawa masu anikela ngezinzuzo eziningana ngaphezulu kokuhlinzwa kwendabuko okuvulekile, okubandakanya: Ubuhlungu obuncishisiwe kanye ne-starring esifushane esibhedlela isikhathi sokuphumula sokubuyisa ngokushesha ama-timesthen kanye nokuncipha kwezinkinga, okwenza kube ukukhetha okuthandwa kakhulu kweziguli ezifanele. Ngolwazi oluthe xaxa ngezinketho zokuhlinza, bonisana nodokotela ohlinzayo ezikhungweni ezifana I-Shandong Baafa Cancer Research Institute, ochwepheshe ngale ndlela ethuthukisiwe.SBRT: I-Stereotactic yomzimba imisebe yokwelashwa kwemisebe yokwelashwa kwemisebe esetshenziselwa ukwelapha amaphaphu amaphaphu, ikakhulukazi ezigulini ezingafaneleki ngokuhlinzwa. I-SBT ihambisa imithamo ephezulu yemisebe ibe yisimila ngenkathi inciphisa ukuvezwa kokulashwa okunempilo okunempilo.Thargeged Therapy, umuthi we-Lung okhansheni osebenzisa izidakamizwa kuwo uluhlobo lwamaseli omdlavuza ngokuqondile ngenkathi unciphisa ukulimala kwamaseli ajwayelekile. Le ndlela ithembele ekuboneni ukuguqulwa okuthile kofuzo noma amaprotheni aqhuba ukukhula komdlavuza.Egfr Inhibitorsepiderrmal Fight Receptor (EGFR) inhibitors asetshenziswa ezigulini ezine-NSFRICS eneziguli. Le mishanguzo ivimba izindlela ezisayiniwe ezikhuthaza ukukhula kweseli yomdlavuza kanye nokusinda.Ilk inhibitorsanaplastic Lymphoma kinase (ALK) inhibitors asetshenziswa ezigulini ezine-NSCLC ezihlehliswa nguGene Gene. Le mishanguzo ivimba umsebenzi wamaprotheni we-ALK, akhipha ukukhula komdlavuza.Imininingwane yezidakamizwa zokwelapha ezihlosiwe zokwelapha ezihlosiwe zivunyiwe ngokwelashwa komdlavuza wamaphaphu. Nazi izibonelo ezimbalwa: I-OSIMERTININIBIB (TARGISYO): I-egfr inhibitor ye-NSCLC enokuguqulwa okuthile kwe-egfr. Crizotinib (xalkori): I-Alk inhibitor ye-NSCLC enokuhanjiswa kabusha kwe-ALK. Bevacizumab (Avastin): I-Vegf inhibitor ehlose ukukhula komkhumbi wegazi ku-tumors.Immunotherapy: Ukuhlanganisa i-immune slidewotherapy uhlobo lomdlavuza osiza amasosha omzimba alwe nomdlavuza. Le ndlela isebenzisa izidakamizwa ezivimba izindawo zokuhlola, okuvumela amasosha omzimba ukuba aqaphele futhi ahlasele amaseli womdlavuza ngokuphumelelayo.Checkpoint Le mishanguzo ivimba amaprotheni avimbela amasosha omzimba ekuhlaseleni amaseli omdlavuza. Izibonelo zifaka: Pembrolikukumab (Keytruda): I-PD-1 inhibitor Nivolumab (Opdivo): I-PD-1 inhibitor I-AtezoLiZumab (Tecentriq): I-PD-L1 inhibitorcar t-cell therapytheliserile hhayi ukwelashwa okujwayelekile kwabadlangi abaningi amaphaphu, ukwelashwa kwe-t-cell cell kukhombisa isithembiso ezimweni ezithile futhi kuyaphenywa ngenhloso yokuvivinywa kwemitholampilo. Lokhu kwelashwa kuhlanganisa ukuguqula amaseli we-T wesiguli ukuze aqaphele futhi ahlasele amaseli womdlavuza.Chemotherapy: Indlela yendabuko enenhlanganisela entsha yokuhlanganiswa ihlala iyingxenye ebalulekile yokwelashwa komdlavuza wamaphaphu, ikakhulukazi izigaba ezithuthukile. Ngenkathi ukwelashwa okusha sekuvele, i-chemotherapy ivame ukusetshenziselwa ukuhlanganiswa nokwelashwa okuhlosiwe noma i-immunotherapy ukwenza ngcono imiphumela ye-coupcomes.cliinical: Ukufinyelela izivivinyo zokwelashwa ezisetshenziswayo yizifundo zokucwaninga ngomdlavuza. Ukubamba iqhaza esivivinyweni somtholampilo kunganikeza ukufinyelela kwezindlela zokwelapha ezisikiwe ezingatholakali kabanzi. Iziguli ezinentshisekelo ezivivinyweni zemitholampilo kufanele zixoxe ngale ndlela nge-Oncologist.Side ukuphathwa kwezomphumela: Ukuthuthukisa ikhwalithi yemiphumela emibi yokuphila kuyingxenye ebalulekile yokwelashwa komdlavuza wamaphaphu. Izindlela eziningi ezintsha zokwelapha, njengokwelashwa okuhlosiwe kanye ne-immunotherapy, zinamaphrofayili we-second affect ahlukile ngokuqhathaniswa ne-chemotherapy yendabuko. Ukuphathwa Okusebenzayo Kwemiphumela Yesihlangotho kungathuthukisa kakhulu ikhwalithi yempilo yeziguli ngesikhathi sokwelashwa.Ikusasa le-LEP RASHRACTRICTRICE HORCHERTITE Inkambu yezokwelapha umdlavuza wamaphaphu ivela ngokushesha. Ucwaningo oluqhubekayo lugxile ekuthuthukiseni ukwelashwa okusha okuhlosiwe, ama-acmwoFarapies, kanye namathuluzi okuxilonga. Lezi Intuthuko ekwelashweni komdlavuza wamaphaphu Bamba isithembiso sokwenza ngcono imiphumela futhi unwebe izimpilo zeziguli ezine-Lung Cancerflect.com (Ushintsho lokwelashwa itafula elilandelayo linikeza ukuqhathanisa okwenziwe lula kwezinketho zamaphaphu. Kubalulekile ukuthintana nodokotela wakho ukuthola uhlelo lokwelashwa olungcono kakhulu lwesimo sakho esithile. Ukwelashwa okujwayelekile sebenzisa izinzuzo ezingaba khona imiphumela emibi ehlinzweni ye-NSCLC enokwenzeka yelaphe ama-chercy amaseli, ukugula, ukukhathala, izinkinga ze-alk) ezinqunyelwe i-NSCLC ethuthukisiwe Izimpendulo kokunye ukusabela kweziguli ze-autoimmune, ukukhathala, ukuqhudelana, ukuvuvukala kwezitho ze-chemotherapy Izigaba ezahlukahlukene zomdlavuza wamaphaphu zingancipha isisindo se-ranceas, ukunqamula, ukuncipha kwezinwele, ukukhathala, ukubalwa kwezitokisi zegazi Ukuzikhulula: Lo mbhalo unikeza imininingwane ejwayelekile futhi akufanele uthathwe njengeseluleko sezokwelapha. Thintana nochwepheshe wezempilo ofanelekayo wesiqondiso esenziwe umuntu ngokuxilongwa komdlavuza wamaphaphu nokwelashwa.