Ukuqonda izinguquko zofuzo ze-brca kanye nokwelashwa komdlavuza we-Prostate eChina

Lo mhlahlandlela ophelele uhlola ukuxhumana phakathi kwezakhi zofuzo ze-brca kanye nezinketho zokwelashwa komdlavuza we-Prostate zitholakala eChina. Sithola imiphumela yalezi zinguquko zofuzo, izinqubo zokuxilonga, kanye nentuthuko yakamuva ezindaweni ezihlosiwe. Funda ngeqhaza lokuhlolwa kwezakhi zofuzo, ukuhlolwa kobungozi kanye namasu okuthola ukwelashwa okwenzelwe abantu abanomdlavuza we-Prostate ohlobene ne-BRCA.

Uhlobo lwe-brca nomdlavuza we-prostate: Ukubukeka okusondele

Yiziphi izinhlobo ze-brca?

I-BRCA1 ne-BRCA2 yizo izinhlobo zofuzo we-suppresressor. Ukuguqulwa kwezinguquko kulezi zifuzo kungakhulisa kakhulu ingozi yokuthola umdlavuza othize, kufaka phakathi umdlavuza we-Prostate. Ngenkathi amakhansela ebele kanye nama-avarari avame ukuhlotshaniswa nokuguqulwa kwe-brca, umzimba okhulayo wokucwaninga ugcizelela isixhumanisi sabo somdlavuza wendlala yesinye futhi. Lokhu kuguqulwa kungathinta indlela ukulungisa indlela ukulungisa indlela yokulimala kwe-DNA, okuholela ekukhuleni kwamaseli okungalawulwa kanye nokwakheka kwesimila.

Ukubaluleka kwe-brca izinguquko ze-brca kumdlavuza we-prostate

Abantu abane-brca cubutho ye-brca bavame ukuba khona ngezindlela ezinolaka komdlavuza we-prostate, ezingathuthuka ngokushesha futhi zingamelana kakhulu nokwelashwa okujwayelekile. Ukutholwa kusenesikhathi namasu okuphatha afanele kubalulekile ekuthuthukiseni imiphumela yamadoda nge China brca geno gene prostate cancer ixhumene ne-brca izinguquko ze-brca. Ukuba khona kwe-run ye-brca nakho kungathonya izinqumo zokwelashwa kanye nokuqanjwa kwe-prognosis.

Ukuxilongwa kanye nokuhlolwa kofuzo kwe-BRCA izinguquko ze-BRCA eChina

Ukuhlonza ama-rust we-brca

Ukuhlolwa kwezakhi zofuzo kuyindlela eyinhloko yokuhlonza izinguquko ze-brca. Lokhu kufaka ukuhlaziya isampula ye-DNA yakho ukuthola noma yikuphi ukuguqulwa kwezakhi zofuzo ze-BRCA1 ne-BRCA2. EChina, izikhungo zokuhlola zofuzo eziningana zinikeza lezi zinsizakalo. Inqubo yokuhlola imvamisa ifaka isampula yegazi noma isampula yethe, ilandelwa ukuhlaziywa kwelebhu. Imiphumela ingasiza ekuhloleni ubungozi bakho obuthile futhi baqondise izinqumo zokwelashwa. Ukutholwa kusenesikhathi ngokuhlola kubalulekile, ikakhulukazi ukucubungula imiphumela engaba khona ye I-China BRCA geno gene Prostate Cancer Terfer.

Ukufinyelela ukuhlolwa kofuzo eChina

Ukutholakala nokutholakala kokuhlolwa kwe-BRCA kungahlukahluka ngezifunda ezahlukahlukene eChina. Ukubonisana nodokotela we-oncologist noma umeluleki wezakhi zofuzo kuyisinyathelo sokuqala sokuthola indlela efanele yokuhlola. Bangakuqondisa ngenqubo futhi bahumushe imiphumela, banikeze izincomo ezenzelwe wena.

Izinketho zokwelashwa komdlavuza we-Prostate ohlobene ne-BRCA eChina

Izindlela zokwelapha ezihlosiwe

Ukuba khona kwe-BRCA MAXATIONS kuvula amathuba okubhekiswa ekwelashweni okuhlosiwe, okuhlose ngokuqondile amaseli omdlavuza ngokuguqulwa kwalezi zinguquko, ukunciphisa ukulimala kwamaseli anempilo. Lezi zindlela zokwelapha zivame ukunikela ngempumelelo futhi zinciphise imiphumela emibi uma kuqhathaniswa nezindlela ezivamile. I-Parp inhibitors iyi-CHARDE yezidakamizwa ezihlosiwe ezikhombisile imiphumela ethembisayo ekwelapheni umdlavuza we-prostate we-brca. Ukutholakala nokusetshenziswa kwalezi zindlela zokwelapha okuhlosiwe kungahluka kuzo zonke izibhedlela ezahlukene eChina. Isazi se-oncologist yakho sizonquma isu elifanele kakhulu lokwelashwa ngesimo sakho esithile.

Ukwelashwa okujwayelekile nendima yabo

Ngenkathi izindlela zokwelapha ezihlosiwe zibalulekile, ukwelashwa okujwayelekile njengokuhlinzwa, ukwelashwa kwemisebe, nokwelashwa kwama-hormone kusadlala indima ebalulekile ekuphatheni China brca geno gene prostate cancer, ngisho nasebukhoneni be-BRCA izinguquko ze-brca. Indlela yokwelashwa efanelekile imvamisa iyinhlanganisela yokwelashwa eyenziwe ngezimo ezithile kanye nezimpawu zomdlavuza.

Ukusekelwa Nezinsizakusebenza zeziguli eChina

Ukuzulazula ekuhlolweni komdlavuza wendlala yesinye kungaba yinselele. Amaqembu ambalwa okusekelwa nezinsizakusebenza ayatholakala eChina ukusiza iziguli nemindeni yazo izici ezingokomzwelo nezisebenzayo zokugula. Ukuxhuma nalawa manethiwekhi okusekela anganikeza ukusekelwa okungokomzwelo okubalulekile nokufinyelela kwisiqondiso esisebenzayo.

Ukunakekelwa komdlavuza okuphelele eChina, cabanga ngokuhlola izinketho ku- I-Shandong Baafa Cancer Research Institute. Banikela ngamakhono okuxilonga athuthukile, ukuhlelwa kokwelashwa okwenziwe ngezifiso, kanye nokufinyelela kochwepheshe abaholayo.

Nesitatimende

Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele lubhekwe njengeluleke lwezokwelapha. Hlala uthintana nomuntu oqeqeshiwe wezokunakekelwa kwezempilo ukuze kuxilongwa kanye nokwelashwa kwanoma yisiphi isimo sezokwelapha.