I-China Renal Cell Carcinoma Pathology

I-China Renal Cell Carcinoma Pathology Ukuchazwa kwe-Pathology of Renal Cell Carcinoma ku-Chinathis Article enikezela ngezinto eziphakeme ze-Chinatis Carcinoma, egxile ekusondleni okutholakalayo, kanye nemithelela ye-prognostic. Sizohlola ukucwaninga kwakamuva nemikhombandlela yezempilo ukunikeza ukuqonda okucacile kwalo mdlavuza ojwayelekile. Lesi sisetshenziswa senzelwe ochwepheshe bezokunakekelwa kwempilo kanye nabaphenyi abanentshisekelo kwi-RCC PAYOLOGY.

Ukubhala kanye nezici zobungozi ze-RCC eChina

I-Renal Cell Carcinoma imele inselelo enkulu yezempilo yomphakathi eChina. Ngenkathi amanani anembile ezehlakalo ahluka esifundeni, ucwaningo luphakamisa umkhuba okhuphukayo, ngokuthola izibuko emhlabeni jikelele. Izici eziningana zengozi zineqhaza ekuthuthukisweni kwe-RCC, kufaka phakathi ukubhema, ukukhuluphala, umfutho wegazi ophakeme, nomlando womndeni. Ngaphezu kwalokho, ukuvezwa kobuthi obuthile bezemvelo kungadlala indima. Ukuqonda lezi zinto zobungozi kubalulekile ekuqaliseni amasu wokuvimbela asebenzayo.

Ukuhlukaniswa kwe-Pathological of RCC

I-subtype evelele ye-The Rightpe of China Renal Cell Carcinoma i-cell cell RCC (CCRCC), ibala inani elibalulekile lamacala. Kodwa-ke, amanye ama-subtypes, afana ne-papillary RCC, i-Chromophobe RCC, kanye nokuqoqa i-DCC, kuyenzeka. Ukuhlukaniswa okunembile kwe-pathological kubaluleke kakhulu ekuqondiseni izinqumo zokwelashwa nokubikezela ukubikezela kwe-prognosis. Amasu wesimanjemanje we-Pathological, okubandakanya i-immunohistochemistry kanye ne-polycale profiling, aqashwa ngokwengeziwe ukuze acwengeke ngokunemba.

Sula iseli le-renal cell carcinoma (CCRCC)

I-CCRCC ibonakala ngokucacile kwe-cytoplasm kumaseli we-tumor ngenxa yokuqukethwe okuningi kwe-glycogen kanye ne-lipid. Imvamisa ikhombisa iphethini yezidleke eziqinile namabhamuza. Izinguquko ezithile zamangqamuzana, njenge-gehl gene izilonda, zivame ukuhlotshaniswa ne-CCRCC. Ukuqonda lezi zici ze-molecular kubalulekile ekuthuthukisweni kwezokwelapha okuhlosiwe.

Amanye ama-subtypes we-RCC

I-Papillary RCC ibonakala ngezinhlaka ezifana ne-papillae-efana, imvamisa ibonisa isibonelelo esihle kakhulu kune-CCRCC. I-Chromophobe RCC ayivamile futhi ibonisa isimilo se-Eosinophilic Cytoplasm. Ukuqoqa i-Duct RCC kuyinto engajwayelekile futhi enolaka. Ukwehluka okunembile phakathi kwalezi zinhlaka eziphansi kubalulekile kumasu wokuthola ukwelashwa.

Ukuxilongwa Kwendlela ye-RCC eChina

Ukuxilonga China Renal Cell Carcinoma Imvamisa kubandakanya inhlanganisela yezifundo zokucabanga (i-CT, MRI) nokuhlolwa kwe-histopathological kwezimpawu ze-biopsy noma zokuhlinzwa. Intuthuko kumasu wokucabanga, kufaka phakathi i-multiphasic CT, ithuthukise ukutholwa kanye nokuhluzeka kwezinqwaba zezinhlamvu. I-Biod-Wistele Aipseverity Biopsy inganikeza imininingwane yokuqala ye-cytological, ngenkathi ukusetha kabusha kokuhlinza kuvumela ukuxilongwa kwe-pathological okuchazayo.

Izici Zombuso kanye Nemiphumela Yokwelashwa

Kunezici eziningana zithonya ukutholwa kwe-RCC, kufaka phakathi isigaba se-tumor (i-TNM STAGH), ibanga lomlando, kanye nokuba khona kwe-metastasis. Uhlelo lwe-TNM Stiluging lunikeza indlela ejwayelekile yokufaka ubungozi. Ngaphezu kwalokho, uhlelo lweFuhrman Grading luhlola izici zenuzi zamaseli e-RCC ukubikezela isimilo esinolaka. Lezi zinto ziqondisa izinqumo zokwelashwa, ezisukela ekuhlelweni kokuhlinzwa kwezindlela ezihlosiweyo kanye ne-immunotherapy.

Ucwaningo Nezindlela Ezizayo

Ukucwaninga okuqhubekayo eChina kugxile ekuthuthukiseni ukutholwa kusenesikhathi, kucwengeze amasu wokuxilonga, kanye nokwakha amanoveli zokwelapha China Renal Cell Carcinoma. Lokhu kufaka phakathi uphenyo olungenakutholwa kusenesikhathi, ukuhlola okuhlosiwe kwenoveli, kanye nezilingo zemitholampilo ezihlola izindlela zokwelashwa ezintsha. Ukusebenzisana phakathi kwabaphenyi, odokotela, kanye nabenzi bezinqubomgomo kubalulekile ukuqhubekisela phambili ukuqonda nokuphatha i-RCC eChina.

Ithebula: Ukuqhathaniswa kwe-RCC ephakeme

Ukuzikhulula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele lubhekwe njengeluleke lwezokwelapha. Hlala uthintana nochwepheshe wezokunakekelwa kwempilo kunoma yikuphi ukukhathazeka ngempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo yakho noma yokwelashwa.

Ngeminye imininingwane ngocwaningo lomdlavuza kanye nezinketho zokwelashwa, sicela uvakashele I-Shandong Baafa Cancer Research Institute.