ukwelashwa okukhulu komdlavuza wamaphaphu

Umdlavuza omkhulu weseli (LCLC) kuyinto enobuntu obunolaka lomdlavuza we-cell ongelona omncane (NSCLC). Izinketho zokwelashwa ziyehluka futhi zincike esigabeni somdlavuza, impilo yonke, kanye nezintandokazi zesiguli. Izindlela ezijwayelekile zibandakanya ukuhlinzwa, ukwelashwa kwemisebe, i-chemotherapy, ukwelashwa okuhlosiwe, kanye ne-immunotherapy. Ukuhlanganisa ukwelashwa kuvame ukuveza imiphumela emihle kakhulu.Uqonde ukuqonda omkhulu umdlavuza wamaphaphu we-LUP ROVACREAT MOREL RECROCE REMPACR?Umdlavuza omkhulu weseli (LCLC) kubonakaliswa amaseli amakhulu, angajwayelekile lapho kubukwa ngaphansi kwesibonakhulu. Ibala cishe ama-5-10% abo bonke amaphuphu amaphaphu. Ngenxa yesimo sayo esinolaka, ukutholwa kanye nokwelashwa kusenesikhathi kubalulekile. Kuyinto ephansi ye-NSCLC, okusho ukuthi iziphatha ngendlela ehlukile futhi iphathwa ngendlela ehlukile kune-Cell Lung Loan Cancer (SCLC). I-LCLC, okunye okufihlayo kungenzeka kwenziwe ekuqondiseni kangcono amasu okulashwa. Lokhu kufaka phakathi: I-Cell Cell Neuroendocrine Carcinoma (LCNEC): Le ncwadi evumayo ihlanganyela izici zombili umdlavuza omkhulu weseli kanye nomdlavuza omncane weseli. I-Basaloid Carcinoma: I-subtype engajwayelekile futhi enolaka. Lymphoepithelioma-like carcinoma: Okuvame kakhulu kubantu abavela e-Asia futhi kuvame ukuhlotshaniswa nokutheleleka ngegciwane le-epstein -br. Sula Carcinoma: Kubonakaliswa amaseli ngokubukeka okucacile noma okungenalutho ngaphansi kwesibonakhulu .I -IAgnosis ye-cell cell aleng fasebeagnosing umdlavuza omkhulu weseli Imvamisa kubandakanya inhlanganisela yokuhlolwa kokucabanga kanye nama-biopsies. Ukuhlolwa kokucabanga: Isifuba i-x-ray: Imvamisa ukuhlolwa kokuqala kokucabanga okwenziwe ukukhomba izinto ezingekho emthethweni emaphashini. I-CT SCAN (I-Compled Comography): Inikeza izithombe ezinemininingwane eminingi yamaphaphu nezinhlaka ezizungezile, ukusiza ukunquma usayizi nendawo yendawo yesimila. I-PET SCAN (I-Positron Emi: I-Positron Emi: Ithola amaseli asebenzayo we-metabolically, isiza ukukhomba izicubu zomdlavuza futhi inqume ukuthi umdlavuza usakaze yini. I-MRI (I-Magnetic Resonance Imaging): Ingahle isetshenziselwe ukuhlola ukusakazeka komdlavuza engqondweni noma emgogodleni. I-Biopsy: Isampula yezicubu zithathwa ukuze ihlolwe ngaphansi kwesibonakhulu. Izindlela ze-Biopsy zifaka: Bronchoscopy: Ishubhu elincanyana eliguqukayo elinekhamera elifakwe ekhaleni noma ngomlomo ungene emaphashini ukuze ubone ngeso lengqondo futhi uqoqe amasampula wezicubu. Inaliti Biopsy: Kufakwe inaliti ngodonga lwesifuba ukuqoqa isampula yezicubu kusuka ku-isimila. Lokhu kungaba yi-CT-kuqondiswe ngokunemba okwengeziwe. Biopsy okuhlinza: Kwezinye izimo, ukuhlinzwa kungadingeka ukuthola isampula eyanele yezicubu. Izinketho ezinkulu zokwelashwa umdlavuza weseli ama-lung acceract ukwelashwa okukhulu komdlavuza wamaphaphu Kuya ngezici eziningana, kufaka phakathi isigaba somdlavuza, impilo yesiguli yonke, kanye nezinto ezizithandayo. Izinketho zokwelashwa zingasetshenziswa zodwa noma ngokuhlanganiswa.Surgerysurgery imvamisa ukwelashwa okukhethwayo kwesigaba sokuqala umdlavuza omkhulu weseli Lapho isimila senziwe sendawo futhi singasuswa ngokuphelele. Izinketho zokuhlinzwa ezifaka phakathi: Ukuvuselelwa kwe-Wedge: Ukususwa kwengxenye encane, eyenziwe nge-wedge ye-Lung equkethe isimila. I-Segmetectomy: Ukususwa kwengxenye enkulu yamaphaphu kunokuvuselelwa kwe-wedge. I-Lobectomy: Ukususwa kwe-lobe yonke yamaphaphu. Pneumonicyy: Ukususwa kozakwethu we-lung.our, I-Shandong Baafa Cancer Research Institute, at baofahospital.com, ngokukhethekile amasu okuhlinza okusha yokwelashwa we-lung cancer.radiation therapyradiation therapy isebenzisa imisebe yamandla aphezulu ukubulala umdlavuza amaseli. Ingasetshenziswa njengokwelashwa okuyinhloko kwe umdlavuza omkhulu weseli Lapho ukuhlinzwa kungeyona inketho, noma kungasetshenziswa ngemuva kokuhlinzwa ukubulala noma yimaphi amaseli omdlavuza asele. Izinhlobo zokwelapha imisebe zifaka: Ukwelashwa kwemisebe yangaphandle yangaphandle (EBRT): Imisebe ihanjiswa emshinini ngaphandle komzimba. Ukwelashwa kwemisebe yemisebe yeStereotactic (SBTT): Ihambisa imithamo ephezulu yemisebe iye endaweni encane, ehlosiwe ngqo. I-Brachytherapy (ukwelashwa kwemisebe yangaphakathi): Imbewu noma izintambo ezinemisebe zibekwa ngqo emsikeni noma eduze kwalesi similo.chemotherotherapychemothemothery isebenzisa izidakamizwa ukubulala umdlavuza. Kuvame ukusetshenziselwa umdlavuza omkhulu weseli okusatshalaliswe ngaphesheya kwamaphaphu noma lapho ukuhlinzwa kungenzeki. Izidakamizwa ze-Chemotherapy zivame ukuphathwa ngokungenamfihlo (ngokusebenzisa umthambo) noma izidakamizwa zokwelapha ze-terapytable ezihlotshisiwe ziqondise ama-molecule athile atholakalayo ekukhuleni kweseli yomdlavuza nokusinda. Le mishanguzo isebenza kakhulu lapho amaseli omdlavuza anezinqumo ezithile zofuzo. Okuhlosiwe okujwayelekile kufaka: I-EGFR (Ukwanda Kokukhula Kwe-Epidermal Isici): Ukuguqulwa kwezakhi ze-egfr kuvame kakhulu kubantu abathile. I-ALK (ANAPLAKY LYMphoma Kinase): I-Alk inhibitors ingasebenza kakhulu ezigulini ezine-alk-positive umdlavuza omkhulu weseli. Ros1: I-ROS1 inhibitors isetshenziselwa ama-tumors we-ros1-ama-ros1 ukwelashwa okukhulu komdlavuza wamaphaphu.I -Immunotherapyimmunmunotherapy isiza amasosha omzimba womzimba alwe nomdlavuza. Le mishanguzo isebenza ngokuvimba amaprotheni avimbela amasosha omzimba ekuhlaseleni amaseli omdlavuza. Izidakamizwa ze-ImmunoSatherapy zivame ukusetshenziselwa ukuthuthuka umdlavuza omkhulu weseli.Stred ngesiteji se-Stagethe umdlavuza omkhulu weseli ukuthonya kakhulu indlela yokwelashwa. Isigaba esijwayelekile sokwelashwa okusondela kusigaba I & II (ekuqaleni kwesigaba) ukuhlinzwa (i-lobectomy noma i-wedge resection) kulandelwa i-chemotherapy uma kunesidingo. Ukwelashwa kwemisebe kungabhekwa nje uma ukuhlinzwa akuyona inketho. Isiteji III (endaweni ethuthukile) inhlanganisela ye-chemotherapy kanye nokwelashwa kwemisebe. Ukuhlinzwa kungabhekwa kumacala akhethiwe. I-ImmunoSatherapy ingahle isetshenziswe ngemuva kwekhemisi. Isigaba IV (Metastatic) Chemotherapy, Therapy okuhlosiwe (uma ukuguqulwa okufanelekile kukhona), kanye ne-immunotherapy. Ukwelashwa kwemisebe kungasetshenziselwa ukudambisa izimpawu. Izilingo ze-Clinical zokuvivinya izivivinyo ziyizifundo zokucwaninga ezihlola okusha ukwelashwa okukhulu komdlavuza wamaphaphu Izinketho. Ukubamba iqhaza esivivinyweni somtholampilo kunganikeza ukufinyelela kwezindlela zokwelapha ezisika futhi kufaka isandla entuthukweni yokwelashwa komdlavuza.Qokwanathi-i-prognosos ye umdlavuza omkhulu weseli Iyahlukahluka ngokuya ngesigaba somdlavuza ekuxilongeni kanye nokwelashwa okutholakele. Ukutholwa kusenesikhathi nokuphathwa ngolaka kungathuthukisa imiphumela. Ukuqokwa okujwayelekile kokuqokwa kubalulekile ekuqapheleni kabusha ukuvela kabusha.Living nge-cell enkulu yamaphaphu umdlavuza omkhulu weseli Ukuxilongwa kungaba nzima. Amaqembu okusekela, ukwelulekwa, nokuguqulwa kwendlela yokuphila (njengokuyeka ukubhema nokugcina ukudla okunempilo) kungasiza iziguli ukuba zibhekane nezinselelo ezingokomzimba nangokomzwelo zalesi sifo.Ukuzikhulula: Lolu lwazi ngolwazi olujwayelekile kanye nezinhloso zolwazi kuphela, futhi alwenzi izeluleko zezokwelapha. Kubalulekile ukuthintana nochwepheshe wezempilo ofanelekayo nganoma yiziphi izinkathazo zezempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo yakho noma yokwelashwa. Izinketho zokwelashwa kufanele zinqunywe nguchwepheshe wezokunakekelwa kwempilo ezisuselwa ezintweni ezifundeni.Izinkomba: I-American Cancer Society: https:/www.cancer.org/ I-National Cancer Institute: https:/www.cancer.gov/