renal cell carcinoma

I-Renal Cell Carcinoma (RCC) luhlobo oluvame kakhulu lomdlavuza wezinso kubantu abadala. Kuvela ekulweni kwe-tubule ye-proximal evumelanisiwe, ingxenye yamashubhu amancane kakhulu ezinso elihlunga igazi futhi lihlanze. Lo mhlahlandlela uhle ukhiphe izinkampani ze renal cell carcinoma, emboza yonke into evela ezintweni ezingozini nezimpawu ukuxilonga, izinketho zokwelashwa kanye nokuqonda kwe-prognosisveكy Renal cell carcinomaYini Renal cell carcinoma?I-Renal Cell Carcinoma (RCC) ngumdlavuza oqala ezinso. Izinso ziyizitho ezimbili ezenziwe ngobhontshisi, ngalinye licishe libe ngosayizi wenqindi, elisemuva kwezitho zakho zesisu, eyodwa ohlangothini lomgogodla wakho. Umsebenzi wabo oyinhloko ukuhlunga imfucuza kanye noketshezi oluningi oluvela egazini lakho, olube selikhishwe kumichamo yakho.Izinhlobo zakho zeDifferent ze renal cell carcinoma zikhona, ngeseli elicacile renal cell carcinoma kokuba okuvame kakhulu. Ezinye izinhlobo zifaka i-papillary renal cell carcinoma, chromophobe renal cell carcinoma, nokuqoqa i-duct renal cell carcinoma.TYTYPES of Renal cell carcinomaUkuqonda uhlobo oluthile lwe renal cell carcinoma kubalulekile ekunqumeni uhlelo olusebenza kahle lokwelashwa. Ezinye izinhlobo ezijwayelekile zifaka: Sula iseli Renal cell carcinoma: Uhlobo oluvame kakhulu, accounting cishe ama-70-80% amacala. Lawa maseli abonakala ecacile ngaphansi kwesibonakhulu. -Maphapillary Renal cell carcinoma: Uhlobo lwesibili oluvame kakhulu (10-15% lwamacala), lubonakala ngokuqagelwa okufana nomunwe. I-Chromophobe Renal cell carcinoma: Ama-akhawunti acishe abe ngu-5% wamacala futhi athambekele ekuhlolweni okungcono kuneseli elicacile renal cell carcinoma. Ukuqoqa i-duct Renal cell carcinoma: Uhlobo olungajwayelekile nolunolaka lwe renal cell carcinoma.Risk Factors for Renal cell carcinomaIzici eziningana zingakhulisa ubungozi bakho bokuthuthuka renal cell carcinoma: Ukubhema: Ukubhema kakhulu kwandisa ingozi. Ukukhuluphala: Ukukhuluphala ngokweqile noma ukukhuluphala kuhlobene nengozi ephezulu. Umfutho wegazi ophakeme: I-Hypertension ingakhuphula amathuba okuthuthuka renal cell carcinoma. Umlando Womndeni: Umlando womndeni womdlavuza wezinso ungaphakamisa ubungozi bakho. Imibandela ethile yofuzo: Izimo ezinjenge-von Hippel-Lindau (VHL) Isifo, iBirt-Hogg-Dubé Syndrome, kanye ne-tuberous sclerosis eziyinkimbinkimbi zingakhulisa ubungozi. I-Dialysis yesikhathi eside: Abantu abanokwehluleka kwezinso obungapheli abadinga i-dialysis yesikhathi eside iba nengozi ephezulu. Ukuchayeka ezintweni ezithile: ICadmium namanye ama-herbicides axhumene nengozi eyengeziwe.Symmots kanye nezimpawu zokuxilongwa Renal cell carcinomaEzigabeni zayo zokuqala, renal cell carcinoma kungenzeka kungabingeli noma yiziphi izimpawu ezibonakalayo. Njengoba isimila sikhula, izimpawu zingafaka: igazi emchameni (i-hematuria) isigaxa noma isisindo ohlangothini noma emuva olungabingelwa khona ezinye izimo, kodwa kubalulekile ukubonana nodokotela Renal cell carcinomaUkuxilonga renal cell carcinoma Imvamisa kubandakanya inhlanganisela yalokhu okulandelayo: Ukuhlolwa ngokomzimba: Udokotela uzokwenza ukuhlolwa ngokomzimba ukubheka noma yikuphi ukungahambi kahle. Ukuhlolwa komchamo: Ukubheka igazi noma okunye ukungahambi kahle emchameni. Ukuhlolwa Kwegazi: Ukuhlola umsebenzi wezinso bese ubheka ezinye izinkomba zomdlavuza. Ukuhlolwa kokucabanga: I-CT SCAN: Imvamisa ukuhlolwa kokucabanga okuyisisekelo kokuxilonga renal cell carcinoma. I-MRI: Anganikeza izithombe ezinemininingwane eminingi yezinso nezicubu ezizungezile. I-Ultrasound: Kungasiza ukwahlukanisa phakathi kwamathumbu aqinile nama-cysts. I-Bone Scan: Uma kukhona izinsolo zokuthi ithanga le-metastasis. I-Biopsy: Isampula elincane lezicubu lisuswa kwizinso futhi lihlolisiswe ngaphansi kwesibonakhulu ukuqinisekisa ukuxilongwa futhi kunqume uhlobo renal cell carcinomaIzinketho ze-.strent for Renal cell carcinomaI-RATEMURGENDERS I-RATEMURGENERS imvamisa ukwelashwa okuyinhloko okwenzelwe okwenziwa kwasendaweni renal cell carcinoma. Izinketho zokuhlinzwa ezifaka phakathi: I-Radical Nephrectomy: Ukususwa kwazo zonke izinso, izicubu ezizungezile, futhi kwesinye isikhathi ama-lymph node aseduze. Ingxenye ye-Nephrectomy eyingxenye: Ukususwa kwesimila kuphela kanye nomugqa omncane wezicubu ezinempilo. Lokhu kuvame ukukhethwa ngamathumbu amancane noma lapho isiguli sinezinso eyodwa kuphela.Non-stickitgesif ukuhlinzwa akuyona inketho noma uma umdlavuza usakaze, ezinye izindlela zokwelapha zingasetshenziswa: Ukwelashwa okuhlosiwe: Izidakamizwa ezibhekise ama-molecule athile athinteka ekukhuleni kweseli yomdlavuza kanye nokusinda. Izibonelo zifaka phakathi ama-tyrosine kinase inhibitors (TKIS) njenge-sunitinib (Sutent) ne-pazopanib (Votrient), kanye ne-MTOR inhibitors efana ne-EverLimus (Afpitor) kanye neTemirolimus (Torisel). I-ImmunoSatherapy: Izidakamizwa ezisiza amasosha omzimba alwe nomdlavuza. Izibonelo zifaka phakathi ama-inhibitors we-PD-1 anjenge-nivolumab (OPDIVO) ne-PEMBROLIZIZIZUMAB (Keytruda), kanye ne-CTLA-4 inhibitors efana ne-IPILAMAB (YERVE). Ukwelashwa kwemisebe: Kusetshenziswa imisebe yamandla aphezulu ukubulala umdlavuza amaseli. Lokhu akujwayele ukusetshenziswa renal cell carcinoma Kepha kungenzeka ukuthi isetshenziselwe ukuphatha ithambo metastasis. Izindlela zokwelapha ezihlanzekile: Usebenzisa ukushisa noma ukubanda ukushabalalisa amaseli womdlavuza. Izibonelo zifaka i-radiofrequency ablation (RFA) kanye nokukhethwa kwe-crsoakwane.Treatment Onerferment Ukuqhathanisa Incazelo imiphumela emibi ye-nephrectomy yazo zonke izinhlungu zezinso, isifo sokopha, ukuncipha kokuvuselelwa kwezokwelapha okubhekisele ekukhuleni kwamaseli womdlavuza, uhudo, ukuqubuka kwesikhumba, Ingcindezi yegazi ephezulu ye-immunewotherapy ikhuthaza amasosha omzimba okuvimbela ukukhathala komdlavuza, ukuqubuka kwesikhumba, ukuhubhula, ukuvuvukala kwezitho zomzimba kanye nokulandela ama-orgnosis okuthinta i-prognosonku renal cell carcinoma kuya ngezinto eziningana, kufaka phakathi: isigaba somdlavuza uhlobo lwe renal cell carcinoma Impilo yesiguli ephelele yokutholwa kokutholwa nokwelashwa okujwayelekile kubalulekile ekuthuthukiseni ukwelashwa kwe-prognosis.follow-up areafter areatre renal cell carcinoma, aphoyintimenti alandelayo alandelayo kubalulekile ukubheka ukuphindaphinda futhi aphathe noma yimiphi imiphumela emibi yokwelashwa. Ukulandela kungafaka izivivinyo zomzimba, ukuhlolwa kwegazi kanye nokuhlolwa kokucabanga.Living ne Renal cell carcinomaUkubhekana namasu nge renal cell carcinoma kungaba yinselele, ngokomzimba nangokomzwelo. Amanye amasu okubhekana nawo afaka phakathi: Ukufuna ukwesekwa okuvela emndenini nakubangani okujoyina iqembu lokusekelwa elikhuluma nokwelashwa noma umeluleki eligcina indlela yokuphila enempilo, kufaka phakathi ukudla okunempilo kanye nokudla okujwayelekile kwe-Baccer Cancer Research Institute futhi Renal cell carcinoma Ukucwaninga I-Shandong Baafa Cancer Research Institute, sizinikezele ekuqhubekiseleni ucwaningo nokwelashwa komdlavuza nokwelashwa, kubandakanya renal cell carcinoma. Isikhungo sethu sigxile ezindleleni ezintsha zokuxilonga nokwelashwa, ngenhloso yokwenza ngcono imiphumela yeziguli emhlabeni jikelele.Ukuzikhulula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele lubhekwe njengeluleke lwezokwelapha. Hlala uthintana nomuntu ochwepheshe bezokunakekelwa kwezempilo ofanelekayo kunoma yikuphi ukukhathazeka ngempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo noma yokwelashwa kwakho.Imithombo: I-American Cancer Society I-National Cancer Institute