Ukuqonda i-Renal Cell Carcinoma Pathology: Umhlahlandlela weziguli nemindeni

Lo mhlahlandlela ophelele uhlola i-pathology ye-renal cell carcinoma (RCC), enikeza imininingwane ebalulekile yabantu kanye nemindeni yabo yokuthola lokhu kuxilongwa. Sizokwenza ezinhlotsheni ezahlukahlukene ze-RCC, izindlela zokuxilonga, kanye nendima ebalulekile ye-pathology etholakala ekunqumeni amasu okulashwa. Ukuqonda i-pathology yakho renal cell carcinoma Kubaluleke kakhulu ekuphathweni okusebenzayo kanye nemiphumela ethuthukisiwe.

Yini i-renal cell carcinoma (RCC)?

Renal cell carcinoma, eyaziwa nangokuthi umdlavuza wezinso, ivela ekulweni kwamabhuzu wezinso. Uhlobo oluvame kakhulu lomdlavuza wezinso, ukubalwa kwabalelwa ku-90% wabo bonke umdlavuza wezinso. I-RCC ihlukaniswe ngamanani ambalwa aphansi, ngalinye linezimpawu ezihlukile ze-pathological kanye nemiphumela yokwelashwa. Ukuqonda la ma-subtypes kubalulekile ekuhleleni okusebenzayo kokwelashwa.

Izinhlobo ze-Renal Cell Carcinoma

Sula Cell Renal Cell Carcinoma

I-Sula Cell RCC iyi-subtype ebaluleke kakhulu kakhulu, ebonakaliswa yi-cytoplasm ecacile kumaseli we-tumor. Lokhu kuvela ngaphansi kwesibonakhulu kungenxa yokuqukethwe okuphezulu kwe-glycogen. Izinketho ze-Prognosis kanye nokwelashwa zingahluka ngokuya esiteji nasebangeni le-RCC ecacile ye-RCC. Imibiko yokucabanga ethuthukisiwe ne-pathology ibalulekile ekutholweni okunembile nokuzihlaziya.

I-Papillary Renal Cell Carcinoma

I-Papillary RCC ibonakala ngamaphethini wokukhula we-papillary (njengomunwe). Kunama-subtypes amabili: thayipha 1 nohlobo 2, ngalinye linezici ezihlukile ze-pathological. Uhlobo 1 luvame ukuhlotshaniswa nesifo esithandekayo ukwedlula uhlobo 2. Izakhi zofuzo futhi zidlala indima ekuthuthukisweni nasekuqhubekeni kwe-papillary RCC.

I-Chromophobe Renal Cell Carcinoma

I-Chromophobe RCC iyi-subtype evamile evamile ekhombisa amaseli nge-pale, noma i-chromophobe, i-cytoplasm. Imvamisa ihlotshaniswa nenkambo engenakuqhathaniswa, okusho ukuqhubekela phambili okuhamba kancane. Kodwa-ke, ukuxilongwa okunembile kanye nezindawo zokugcina zihlala zibalulekile ngezinqumo ezifanele zokwelashwa.

Amanye ama-subtypes

Ezinye ama-subtypes ajwayelekile ajwayelekile we renal cell carcinoma Faka ukuqoqa i-duct carcinoma, i-medullary carcinoma, ne-rcc engaqondakali. Lawa ma-subtypes avame ukwethula ngezimpawu ezihlukile futhi angadinga izindlela ezikhethekile zokuxilonga kanye namasu wokwelashwa.

Indima ye-pathology ekuxilolongeni kwe-RCC kanye nokwelashwa

I-Pathology idlala indima ebalulekile ekuhlolweni nasekuzindeni renal cell carcinoma. I-biopsy, imvamisa etholwa ngesifiso senaliti noma inqubo yokuhlinzwa, ibalulekile ekuhlolweni kwesiMicroscopic. I-pathologist ye-pathologist izohlola izici zikamusi, kufaka phakathi usayizi wayo, ibanga, kanye nokuba khona kwama-metastases (ukusabalala umdlavuza kwezinye izingxenye zomzimba). Lolu lwazi lubalulekile ekunqumeni isigaba somdlavuza nokukhetha indlela efanele yokwelashwa.

Ukuthola ukunakekelwa kochwepheshe kwe-renal cell carcinoma

Lapho ubhekene nokuxilongwa kwe renal cell carcinoma, ukhetha isibhedlela nabanezincwadi ezinolwazi ze-pathologists kanye ne-oncologists kubalulekile. Izibhedlela ezinezikhungo zomdlavuza eziphelele zivame ukunikela ngamaqembu amaningi, ukuqinisekisa iziguli zithola ukunakekelwa okuphelele kanye nentuthuko yokwelashwa yakamuva. Ngokwesibonelo, I-Shandong Baafa Cancer Research Institute Kunikezelwe ekunikezeni ukunakekelwa okuthuthukile kweziguli ezinomdlavuza, okunikeza amandla okuxilonga isimo kanye nezinketho zokwelashwa.

Isitebhisi kanye nokufakwa kwe-renal cell carcinoma

Isigaba se renal cell carcinoma Kubonisa ubukhulu bokusakazeka komdlavuza, ngenkathi leli banga libonisa ubulahlo bamaseli we-tumor. Kokubili isigaba nebanga kubalulekile ekunqumeni ukuqondiswa kwe-prognosis kanye nokwelashwa. Imibiko ye-Pathology ihlinzeka ngemininingwane enemininingwane ngalezi zici, okuqondisa odokotela ezinqumweni zabo zokwelashwa.

Izinketho zokwelashwa zeRenal Cell Carcinoma

Ukwelashwa renal cell carcinoma Iyahlukahluka ngokuya ngezinto eziningana, kufaka phakathi isigaba nebanga lomdlavuza, impilo yesiguli ephelele, kanye nokuthandwa ngumuntu. Izinketho zingafaka ukuhlinzwa, ukwelashwa okuhlosiwe, i-immunotherapy, ukwelashwa kwemisebe, noma inhlanganisela yalezi zindlela. Ukutholwa kwe-Pathologists kudlala indima ebalulekile ekuqondiseni ukukhethwa kokwelashwa okufanele kakhulu.

Ukuzikhulula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele lubhekwe njengeluleke lwezokwelapha. Hlala uthintana nochwepheshe wezokunakekelwa kwempilo ukuze uthole ukutholakala nokwelashwa kwanoma yisiphi isimo sezokwelapha.