Ukwelashwa komdlavuza we-Prostate ohlobene ne-BRCA: Izinketho zesibhedlela

Lo mbhalo uhlinzeka ngemininingwane ephelele Ukwelashwa komdlavuza we-prostate ohlobene ne-brca, ukuhlola izinketho nokucatshangelwa okutholakalayo kweziguli. Sizokweluleka ngemininingwane yezakhi zofuzo ze-brca kanye nomthelela wazo kumdlavuza wendlala yesinye, futhi sixoxe ngokubaluleka kokufuna ukunakekelwa kochwepheshe abanolwazi lwezokwelapha.

Ukuqonda ukuguqulwa kofuzo kwe-brca nomdlavuza we-prostate

Yiziphi izinhlobo ze-brca?

I-BRCA1 ne-BRCA2 yizo izinhlobo zofuzo we-suppresressor. Ukuguqulwa kwalezi zinguquko zandisa kakhulu ingozi yokuthola umdlavuza onzulu, kufaka phakathi umdlavuza we-Prostate. Abantu abanezinqumo ze-gene gene ze-brca zivame ukubakhona ngezindlela ezinolaka kakhulu ngalesi sifo, okungenzeka ukuthi bafune amasu ahlukene wokwelashwa ngokuqhathaniswa nalabo ngaphandle kokuguqulwa.

Umthelela we-brca izinguquko ze-brca kumdlavuza we-prostate

Umdlavuza we-Prostate emadodeni ane-brations ye-brca evame ukutholakala eneminyaka emincane futhi angaqhubeka ngokushesha okukhulu. Imvamisa ikhombisa izici ezithile ezithonya izinqumo zokwelashwa. Ukuqonda okushiwo ukuguqulwa kwe-BRCA kubalulekile ekuphathweni okusebenzayo kwalesi sifo.

Izinketho zokwelashwa zomdlavuza we-prostate we-BRCA

Indawo kadokotela

Izinketho zokuhlinza, njenge-prostatectomy enjenge-gland ye-radical (ukususwa kwe-prostate gland), kungabhekwa njengokubi nangokonakala komdlavuza kanye nolaka lomdlavuza. Isinqumo sokuphishekela ukuhlinzwa sifaka ukucubungula ngokucophelela impilo yesiguli kanye nezimpawu zomdlavuza. Ukubonisana nodokotela ohlinzayo ungokobuchwepheshe ababalulekile.

Ukwelashwa kwemisebe

Ukwelashwa kwemisebe, kufaka phakathi imisebe yangaphandle yangaphandle kanye ne-brachytherapy (imisebe yangaphakathi), kungenye indlela evamile yokwelashwa. Ukukhetha phakathi kwalezi zindlela kuncike ezicini eziningana, kufaka phakathi indawo nobungako besimila. I-radiation oncologists esebenza ngokukhethekile ekwakheni izinhlelo zokwelashwa kwemisebe ezenziwe ngezifiso.

I-Hormone Therapy (Therapy ye-androgen dischivation - adt)

Ukwelashwa kweHormone, eyaziwa nangokuthi i-Androgen Dischivation Therapy (ADT), ihlose ukunciphisa amazinga ama-hormone wesilisa (ama-androgens) akhulisa umdlavuza womdlavuza we-prostate. I-ADT ingasetshenziswa yedwa noma inhlanganisela nezinye izindlela zokwelapha. Imiphumela yesikhathi eside ye-ADT idinga ukuqapha ngokucophelela.

Ukwelashwa okuhlosiwe

Izindlela zokwelapha ezihlosiwe zenzelwe ukuhlasela amaseli womdlavuza ngokuqondile ngenkathi zinciphisa ukulimala kwamaseli anempilo. Izindlela eziningi zokwelapha ezihlosiwe zibonisa isithembiso ekwelapheni umdlavuza we-prostate we-brca, ikakhulukazi lezo ezivimbela i-parp (poly adp-ribmerase) enzyme. Lezi zindlela zokwelapha zivame ukusetshenziswa ezigabeni ezithuthukile zesifo.

Chemotherapy

I-Chemotherapy ukwelashwa okuhlelekile okusebenzisa izidakamizwa ukubulala amaseli womdlavuza emzimbeni wonke. Yize kungenjalo ukwelashwa komugqa wokuqala womdlavuza we-BRCA-Fuated Prostate, kungadlala indima ekuphatheni isifo esithuthukile noma se-metastatic.

Ukukhetha isibhedlela esifanele ukwelashwa

Ukukhetha isibhedlela Ukwelashwa komdlavuza we-prostate ohlobene ne-brca yisinqumo esibucayi. Funa izibhedlela nge:

• Onolwazi lwe-Oncologists kanye nodokotela be-urologists abasebenza ngomdlavuza we-Prostate.
• Ukufinyelela kubuchwepheshe obuthuthukile bokuxilonga nokwelashwa.
• Indlela ebanzi yethimba leqembu elihlangene elibandakanya ochwepheshe abahlukahlukene.
• Izinsizakalo ezisezingeni eliphakeme ukunakekelwa kweziguli nezinsizakalo zokusekela.

Ezigulini ezifuna ukunakekelwa komdlavuza okuphelele eChina, The I-Shandong Baafa Cancer Research Institute yisikhungo esiholayo esinikezelwe ekuhlinzekeni ukwelashwa nokusika onqenqemeni. Banikela ngezinsizakalo ezahlukahlukene, kufaka phakathi ukuxilongwa okuthuthukile, amasu okwenziwa owenziwe ngezifiso, nokunakekelwa kweziguli okuqhubekayo.

Ukucatshangelwa Okubalulekile

Indlela engcono kakhulu yokwelashwa Umdlavuza we-prostate ohlobene ne-brca Kuya ngezinto eziningi, kufaka phakathi isigaba somdlavuza, impilo yesiguli ephelele, kanye nokuthandwa ngumuntu. Ukuxhumana okuvulekile nethimba lakho lezempilo kubalulekile kuyo yonke inqubo yokwelashwa.

Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele lubhekwe njengeluleke lwezokwelapha. Hlala uthintana nomuntu ochwepheshe bezokunakekelwa kwezempilo ofanelekayo kunoma yikuphi ukukhathazeka ngempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo noma yokwelashwa kwakho.

Ukuzikhulula: Lolu lwazi lungelolwazi olujwayelekile futhi alukha ngezeluleko zokwelashwa. Xhumana nodokotela wakho ukuthola ukuxilongwa nokwelashwa.