Izindlela ezintsha zokwelashwa komdlavuza wamaphaphu: 2020 nangale kwalokho

Le ndatshana ihlinzeka ngesibukezo sentuthuko ebalulekile ku Ukwelashwa New Lung Rancranced Treakthrourry Precicy 2020 nangale kwalokho. Sihlola intuthuko ebalulekile ekwelashweni okuhlosiwe, ama-emcynotherapies, nezinye izindlela ezintsha, ezigxile ekusebenzeni kwazo kanye nomthelela ongaba khona emiphumeleni yeziguli. Funda mayelana nocwaningo lwakamuva nokuqhubeka kwezilingo zomtholampilo ezakha ikusasa lokunakekelwa komdlavuza wamaphaphu.

Izindlela zokwelapha ezihlosiwe: umuthi we-PRIRPION uthatha isigaba sesikhungo

Intuthuko ku-EGFR ne-ALK inhibitors

Inqubekela phambili enkulu yenziwe ezindaweni ezihlosiwe, ikakhulukazi ezigulini ezinokuguqulwa okuthile kwezakhi zofuzo. Ukwelashwa New Lung Rancranced Treakthrourry Precicy 2020 Sabona ukuvunywa kwama-EGFR amasha amasha kanye ne-ALK inhibitors, enikeza ukusebenza kahle nokubekezelelana ngokuqhathaniswa nezizukulwane zangaphambilini. Lezi zidakamizwa zihlose amaseli womdlavuza ngokutholwa ngalezi zinguquko, ukunciphisa ukulimala kwezicubu ezinempilo. Isibonelo, ukuthuthukiswa kwesizukulwane sesizukulwane sesithathu kukhombisa ukuthethekisa ekunqobeni ukunqoba ukumelana nokwelashwa kwangaphambili. OKhene oqhubekayo uyaqhubeka nokuhlola amandla alezi zindlela zokwelapha ezihlosiwe zihlanganisa nezinye izindlela zokwelapha.

Ama-EmmunoSapies: Ukuhlanganisa amandla amasosha omzimba

Ukuhlola inhibitors kanye neqhaza labo ekwelashweni komdlavuza wamaphaphu

Ama-acmunotherapies, ahlanganisa amasosha omzimba uqobo okulwa nomdlavuza, aguqule Ukwelashwa New Lung Rancranced Treakthrourry Precicy 2020. Ukuhlola ama-inhibitors, njenge-PD-1 ne-PD-L1 inhibitors, kubonise impumelelo emangalisayo ekwandiseni ukusinda ezigulini ezinomdlavuza wamaphaphu athuthukile. Le mishanguzo ivimba amasignali wokuthi amaseli omdlavuza asetshenziswa ukugwema amasosha omzimba, avumele amaseli wokuzivikela emzimbeni ahlasele futhi abhubhise isimila. Kodwa-ke, akuzona zonke iziguli ezisabe ama-Im-immunotherapy, futhi ucwaningo luyaqhubeka ukukhomba ama-biomaskers ukubikezela ukuthi yiziphi iziguli ezizozuzisa kakhulu. Ngaphezu kwalokho, izifundo zihlola ukusetshenziswa kwe-immunotherapy ngokuhlanganiswa nezinye izindlela zokwelapha, njenge-chemotherapy noma ukwelashwa okuhlosiwe, ngokusebenza kahle.

Ezinye izindlela ezithembisayo

Ukwelashwa okusafufusa kanye nokuhlolwa okuqhubekayo kwemitholampilo

Ngaphezu kwezindlela zokwelapha ezihlosiwe kanye nama-accunotherapies, ezinye izindlela eziningi ezithembisayo ziyaphenywa Ukwelashwa New Lung Rancranced Treakthrourry Precicy 2020. Lokhu kufaka phakathi ama-regimens we-checonorapy ama-regimens, ukuthuthuka kwemisebe (okufana ne-stereotactic body radiotherapy noma i-SBRT), nezinhlelo ezintsha zokulethwa kwezidakamizwa. Izilingo eziningi zemitholampilo ziyaqhubeka, zihlola ukusebenza kwalezi zindlela zokwelapha ezintsha nokuhlola inhlanganisela engaba khona ukuze uzuze imiphumela. Ukuhlala unolwazi mayelana nokulingwa okuqhubekayo kwemitholampilo kubalulekile ezigulini nasemindenini yazo zifuna izinketho zokwelashwa ezisethuthuke kakhulu. I-ClinicalTrials.gov Ingabe insiza ebalulekile yokuthola ulwazi ngezilingo zamanje.

Ikusasa lokwelashwa komdlavuza wamaphaphu

Isimo sokuphathwa komdlavuza wamaphaphu sihlala sivela, ngokucwaninga okuqhubekayo kanye nentuthuko ecindezela imingcele yalokho okungenzeka. Ukuhlanganiswa kwemithi eqondile, i-immunotherapy, nezinye izindlela ezintsha zibonisa isithembiso esikhulu sokwenza ngcono imiphumela yeziguli namanani okusinda. Kubalulekile kubantu ababhekene nokuxilongwa komdlavuza wamaphaphu ukubheka ne-Oncologist yabo ukuze baxoxe ngecebo elifanele lokwelashwa elihambisana nesimo sabo esithile nakwiphrofayili yofuzo. Ukunakekelwa komdlavuza okuphelele, cabanga ngokuhlola ubuchwepheshe obutholakala ezikhungweni ezinjenge I-Shandong Baafa Cancer Research Institute.

Ukuqhathaniswa kwedatha: Intuthuko yokwelashwa ebalulekile ()

QAPHELA: Lolu lwazi lungenxa yolwazi olujwayelekile kanye nezinhloso zolwazi kuphela, futhi alwenzi izeluleko zezokwelapha. Hlala uthintana nomuntu ochwepheshe bezokunakekelwa kwezempilo ofanelekayo kunoma yikuphi ukukhathazeka ngempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo noma yokwelashwa kwakho.