Ukwelashwa okusha kwemisebe yokwelashwa komdlavuza wamaphaphu

Ukwelashwa komdlavuza wamaphaphu kuvela ngokushesha, nge Ukwelashwa kwemisebe entsha yomdlavuza wamaphaphu ukunikela ngemiphumela ethuthukisiwe kanye nemiphumela emibi embalwa. Lo mbhalo uhlola intuthuko yakamuva ekwelashweni kwemisebe yomdlavuza wamaphaphu, izinzuzo nokucatshangelwa kweziguli nemindeni yazo i-Cancerlung kanye nomdlavuza wezindlela zokwelashwa kuyimbangela yokufa okuhlobene nomdlavuza emhlabeni wonke. Izindlela zokwelashwa ziyahlukahluka ngokuya ngesigaba nohlobo lomdlavuza wamaphaphu, kanye nempilo yesiguli yonke. Izinhlobo zokwelashwa ezijwayelekile zifaka ukuhlinzwa, chemotherapy, ukwelashwa okuhlosiwe, i-immunotherapy, futhi ukwelashwa kwemisebe. Lesi sigaba sizogxila ngqo kwiseluleko kanye nama-nuances ngaphakathi Ukwelashwa kwemisebe yomdlavuza wamaphaphu..Qophela onomdlavuza wamaphaphu, kunezinhlobo ezimbili eziphambili: umdlavuza we-cell ongelona omncane (NSCLC) kanye nomdlavuza omncane we-cell luyeng. I-NSCLC ivame kakhulu futhi ihlanganisa ama-subtypes amaningana, kufaka phakathi i-adenocarcinoma, i-squamous cell carcinoma, kanye ne-carcinoma enkulu ye-carcinoma enkulu. I-SCLC ivame ukuba nolaka ngokwengeziwe futhi ivame ukuhlotshaniswa nokubhema.Imbani yokwelashwa kwemisebeUkwelashwa kwemisebe Isebenzisa imisebe yamandla aphezulu ukubulala amaseli womdlavuza noma ukuncipha kwamathumbu. Ingasetshenziswa njengokwelashwa okuyinhloko, noma ngokuhlanganiswa nezinye izindlela zokwelapha ezinjenge-chemotherapy noma ukuhlinzwa. Intuthuko yezobuchwepheshe yenziwe Ukwelashwa kwemisebe yomdlavuza wamaphaphu Okuhle kakhulu futhi okusebenzayo, ukunciphisa ubungozi bomonakalo wokuzungeza izicubu ezinempilo ezizungezile ukwelashwa kwemisebe Amasu aqhamuke eminyakeni yamuva nje, enikeza imiphumela ethuthukisiwe kanye nemiphumela emibi encishisiwe yeziguli ezinomdlavuza wamaphaphu. Lokhu kufaka phakathi: I-Stereotactic body radiotherapy (SBTT) SCRT, eyaziwa nangokuthi i-stereotactic a radiotherapy (SABR), ihambisa imithamo ephezulu ye imisebe esimigcani esibhekiswe ngqo kumaseshini okulashwa ambalwa. Le ndlela isebenza ngokukhethekile kumdlavuza omncane, osezingeni eliphezulu wamaphaphu kanye neziguli ezingafaneleki ezifanele zokuhlinzwa. Ukunemba kwe-SBT kunciphisa ukulimala kwezicubu zamaphaphu ezinempilo. Ucwaningo olushicilelwe e- * International Journal of Radiation Oncology, Biology, i-physics * ikhombisa amanani amahle okulawula endawo nge-SBTT ye-NSCLC yesigaba sokuqala (umthombo). I-SBRT imele intuthuko ebalulekile ngaphakathi Ukwelashwa kwemisebe yomdlavuza wamaphaphu, Ukwenza ngcono imiphumela yeziguli eziningi ze-radiosurgery (SRS) ngenkathi ama-SRS evame ukuhlotshaniswa nama-tumors obuchopho, futhi kungasetshenziselwa ukwelapha ama-tumors amaphaphu asakazekele ebuchosheni. Kuyafana ne-SBRT ngoba ukuletha ukugxila kakhulu imisebe imithamo. Le ndlela egxile kakhulu inciphisa ukuvezwa kwezicubu ezizungezile, ukunciphisa imiphumela emibi engaba khona. I-SRS iyithuluzi elibalulekile ekuphatheni isifo semetastatic esivela kusuka umdlavuza wamaphaphuI-radiation ye-radiation ye-radixy elungiselelwe (IMRT) i-IMRT imisebe ugongolo ukuze uhambisane nokwakheka kwesimila. Lokhu kusiza ekuphuphiseni izicubu ezinempilo futhi kunciphise imiphumela emibi. I-IMRT ilusizo ikakhulukazi ekwelashweni ama-tumors akhiwe eduze kwezakhiwo ezibucayi, njengezinhliziyo nentambo yomgogodla. Ngokuguqula ubukhulu be imisebe I-Beams, i-IMRT inikeza indlela ebhekiswe kakhudlwana futhi ephumelelayo Ukwelashwa kwemisebe yomdlavuza wamaphaphu. E- I-Shandong Baafa Cancer Research Institute, sivame ukusebenzisa i-IMRT ukukhulisa ukulawulwa kwesimila ngenkathi kunciphisa ukuphazamiseka kweziguli.Proton Therapyproton Therapy uhlobo lomculo wangaphandle ukwelashwa kwemisebe esebenzisa ama-protons esikhundleni se-x-ray. Amaphrotheni afaka amanani amandla awo amaningi ekujuleni okuthile, okungasiza ukunciphisa imisebe dose ukuzungeza izicubu ezinempilo. I-Proton Therapy iwusizo ikakhulukazi ekwelashweni ama-tumors atholakala eduze kwezitho ezibucayi. Ngenkathi kungenjalo atholakala kabanzi njengabanye imisebe amasu, imelela inketho ethembisayo yokuqiniseka umdlavuza wamaphaphu amacala. Kubalulekile ukuthintana nodokotela wakho we-oncologist ukuthola ukuthi ngabe i-proton therapy ilungele yini isimo sakho esithile. Inzuzo ye-Proton Therapy ilele emandleni ayo okubhekisisa ngokunembile lesi simila ngenkathi usindisa izicubu ezinempilo. Izinzuzo Zokudla Kwemisebe Yemisebe entsha ku Ukwelashwa kwemisebe yomdlavuza wamaphaphu Nikeza izinzuzo ezimbalwa uma kuqhathaniswa namasu endabuko: Ukulawulwa kwezikhukhula okuthuthukisiwe okuncishisiwe imiphumela emibi ye-Times Times ithuthukise imiphumela kanye nokuphathwa kwabaphathi ukwelashwa okusha kwemisebe Amasu ahlose ukunciphisa imiphumela emibi, ezinye iziguli zisengase zibe nakho. Imiphumela emibi ejwayelekile ifaka ukukhathala, ukucasuka kwesikhumba, ukukhwehlela kanye nobunzima bokuphefumula. Le miphumela emibi imvamisa ingeyesikhashana futhi ingalawulwa ngemithi nokunakekelwa kokusekela. Kubalulekile ukuxhumana noma yimiphi imiphumela emibi eqenjini lakho lezempilo ngokushesha ukuze akwazi ukuhlinzeka ngokungenelela okufanele.kungenelela iziguli kanye nemindeni efanelekile ukwelashwa kwemisebe indlela idinga ukucubungula ngokucophelela kwezici eziningana, kufaka phakathi isigaba nohlobo lwe umdlavuza wamaphaphu, impilo yesiguli yonke, kanye nezinto ezizithandayo. Kubalulekile ukudingida zonke izinketho zokwelashwa ne-radiation oncologist eqeqeshiwe ukuthola inkambo efanelekayo kunazo zonke. Nayi itafula elifingqiwe elibalulekile lokucatshangelwa okubalulekile: I-Factor Devation Cancer Stage Spar-Stage Descers ingahle ilungele i-SBT, ngenkathi umdlavuza ethuthukile kakhudlwana angadinga ukwelashwa kwe-IMRT noma amaphrotheni ahambisana nezinye izindlela zokwelapha. Ama-Tumor Indawo Yendawo Eseduzane nezakhiwo ezibucayi angazuza ekwelashweni kwe-IMRT noma kwe-Proton ukunciphisa ukuvezwa kwemisebe ezicubu ezinempilo. Iziguli Zempilo Yeziguli ezinezimo zempilo ezingaphansi zidinga indlela yokwelashwa eguquliwe yokunciphisa ubungozi bezinkinga. Izinhloso zokwelashwa Uhlelo lokwelashwa kufanele livumelane nezinhloso zesiguli, noma ngabe kungokwelapha umdlavuza, lilawule ukukhula kwalo, noma linciphise izimpawu. Ikusasa lokwelashwa kwemisebe yamaphaphu Cansressearch kanye nentuthuko ku Ukwelashwa kwemisebe yomdlavuza wamaphaphu bayaqhubeka. Intuthuko yesikhathi esizayo ingafaka: I-Adaptive Radiation Therapy, elungisa uhlelo lokwelashwa olususelwa kuzinguquko ngosayizi kanye nokwakheka kwesimila ngesikhathi sokwelashwa. Ukuhlanganisa imisebe Nge-Im-i-Im-i-Im-i-Im-i-Im -lackapy ukuthuthukisa ukusabela komzimba komdlavuza emdlavuza. Ukuthuthukisa izidakamizwa ezintsha ezenza amaseli womdlavuza azwela kakhulu imisebe.ConclusionUkwelashwa kwemisebe entsha yomdlavuza wamaphaphu Inikeza ithemba lemiphumela ethuthukisiwe kanye nekhwalithi engcono yempilo yeziguli. Ukuqonda amasu ahlukile, izinzuzo, kanye nokucatshangelwa kubalulekile ngokwenza izinqumo ezinolwazi mayelana nokwelashwa. Thintana ne-radiation oncologist efanelekile, njengaleyo I-Shandong Baafa Cancer Research Institute, ukunquma okufanele kakhulu ukwelashwa kwemisebe hlela isimo sakho esithile.