Ukuthola okulungile Ukwelashwa okungeyona i-Cell Celle Curner Lung Trancer Tarract eduze kwami

Lo mhlahlandlela ophelele kukusiza ukuba uzulazule ubulukhuni bokuthola okusebenzayo Ukwelashwa okungeyona okuncane kwe-LAMUS (NSCLC) Izinketho eduze kwakho. Sihlola izindlela ezahlukahlukene zokwelashwa, ukucatshangelwa kokukhetha ukunakekelwa okulungile, nezinsizakusebenza ukusiza uhambo lwakho.

Ukuqonda umdlavuza wamaphutha ongewona omncane

Yini i-NSCLC?

Umdlavuza wama-cell ongewona omncane uluhlobo oluvame kakhulu lomdlavuza wamaphaphu, accounting cishe ama-80-85% awo wonke umdlavuza wamaphaphu. Ihlukaniswe ngamanani ambalwa aphansi, ngalinye linezimpawu ezihlukile ezithinta amasu wokwelashwa. Ukutholwa kusenesikhathi kubalulekile ukuthola imiphumela ethuthukisiwe. Ukuqonda i-NSCLC subtype yakho ethile kuyisinyathelo esingukhiye ekunqumeni inkambo enhle kakhulu ye Ukwelashwa okungeyona i-Cell Celle Curner Lung Trancer Tarract eduze kwami.

Ukugoqa nokuxilonga

Ukunquma okunembile - ukunquma ubukhulu bomdlavuza - kubalulekile ekuhleleni Ukwelashwa okungeyona i-Cell Celle Curner Lung Trancer Tarract eduze kwami. Lokhu kufaka phakathi izivivinyo ezahlukahlukene, kufaka phakathi ukuskena kokucabanga (CT, PET), Biopsies, kanye nokuhlolwa kwegazi. Isiteji sibonisa indlela efanelekile yokwelashwa. Isibonelo, i-NSCLC yesigaba sokuqala ingalashwa ngokuhlinzwa yedwa, ngenkathi izigaba ezithuthukile zingadinga inhlanganisela yokwelashwa.

Izinketho zokwelashwa ze-NSCLC

Indawo kadokotela

Ukususwa kwe-tumor kuyindlela yokuqala yokwelashwa ye-NSCLC yesigaba sokuqala. Inqubo ethile incike endaweni kanye nosayizi kamusi. Lokhu kungafaka phakathi kwe-lobectomy (ukususwa kwe-lobe yamaphaphu), i-pneumonectomy (ukususwa kwalo lonke amaphaphu), noma i-wedge resection (ukususwa kwengxenye encane yamaphaphu). Ukuhlinzwa ngemuva, ukuvuselelwa kubalulekile ukuthola kabusha.

Chemotherapy

I-Chemotherapy isebenzisa izidakamizwa ukubulala umdlavuza amaseli. Ngokuvamile kuqashwa ngaphambi kokuhlinzwa (i-neadjun) ukuncipha isimila, ngemuva kokuhlinzwa (i-adgevant) ukuqeda amaseli omdlavuza asele, noma njengokuphathwa okuyisisekelo kwe-NSCLC ethuthukisiwe. Izidakamizwa ezijwayelekile ze-chemotherapy ze-NSCLC zifaka i-cisplatin, i-carboplatin, i-paclitaxel, ne-doncetaxel. Imiphumela emibi iyahlukahluka kepha imvamisa ingalawulwa ngokunakekelwa okusekelwayo.

Ukwelashwa kwemisebe

Ukwelashwa kwemisebe kusebenzisa imisebe ephezulu kakhulu ukulimaza nokubhubhisa amaseli womdlavuza. Ingasetshenziswa yedwa, ngaphambi noma ngemuva kokuhlinzwa, noma ukuhlanganiswa nge-chemotherapy. Imisebe yangaphandle ye-beam yangaphandle isetshenziswa kakhulu, iletha imisebe evela emshinini ongaphandle komzimba. Kwezinye izimo, i-brachytherapy (imisebe yangaphakathi) ingabhekwa.

Ukwelashwa okuhlosiwe

Izidakamizwa zokwelapha ezihlosiwe zigxile kuma-molekyuli athile ngaphakathi kwamaseli womdlavuza, ukuphazamisa ukukhula kwazo nokusinda. Lezi zindlela zokwelapha zisebenza ngokukhethekile ezigulini ze-NSCLC ezinokuguqulwa okuthile kofuzo, njenge-egfr, i-alk, noma i-ros1 dech. Ukuhlolwa njalo ukuthola ukuthi lokhu kuguqulwa kubalulekile ukuthola ukufaneleka kwezindlela zokwelapha ezihlosiwe. Izibonelo zifaka i-Osimertinib (Tagrisso), Crizotinib (Xalkori), ne-Afatiinib (GiloTrif).

I-ImmunoSatherapy

I-ImmunoSatherapy ihlanganisa amasosha omzimba wokulwa nomdlavuza. Isebenza ngokuphakamisa amandla amasosha omzimba wokubona nokuhlasela amaseli womdlavuza. Izidakamizwa ze-Immunotherapy, ezinjenge-pembrolikumab (Keytruda) kanye ne-nivolumab (OPDIVO), zisebenza ezigulini ezithile ze-NSCLC, zivame ukuhlanganiswa nge-chemotherapy noma ezinye izindlela zokwelapha. Imiphumela emibi ingafaka ukukhathala, izikhumba izikhumba, kanye nemicimbi ehlobene nokugula okuhlobene nokugula.

Ukuthola ukwelashwa okulungile eduze kwakho

Ukukhetha isikhungo sokwelashwa

Ukukhetha isikhungo se-Oncology esiqeqeshiwe kubaluleke kakhulu. Funa izikhungo ezinabane-oncologists abanolwazi, ubuchwepheshe obuthuthukile, kanye nerekhodi eliqinile lethrekhi ekwelashweni kwe-NSCLC. Cabanga ngezinto ezinjengobuso ekhaya lakho, idumela lesikhungo, kanye nokutholakala kokwelashwa okukhethekile, izivivinyo zemitholampilo kanye nezinsizakalo zokusekela. Bheka ukubuyekezwa okuku-inthanethi futhi ufune izincomo ezivela kudokotela wakho wokunakekelwa noma ochwepheshe bezempilo abathembekile.

Izilingo Zomtholampilo

Ukubamba iqhaza kwecala lomtholampilo kunikeza ukufinyelela kokutholwa kokwelashwa okuma eceleni kungatholakali kabanzi. Lezi zivivinyo zenzelwe ngokucophelela ukuvivinya izindlela zokwelapha ezintsha futhi zithuthukise imiphumela yokwelashwa. Isazi se-oncologist yakho singakusiza ekuboneni ukuthi ngabe kucace yini ukuqulwa kwecala lomtholampilo ngesimo sakho esithile. Ungahlola futhi imininingwane yesivivinyo somtholampilo efana ne-ClinicalTrials.gov ukuthola izifundo ezifanele.

Ukusekelwa Nezinsizakusebenza

Ukuzulazula kungaxilongwa umdlavuza. Funa ukusekelwa okungokomzwelo nangokoqobo ngamaqembu okusekelana, izinhlangano zomdlavuza (e.g., The American Lung Association, The Amaphaphu Cancer Foundation of America), kanye nezinsizakalo zokwelulekwa. Lezi zinsizakusebenza zinikeza imininingwane ebalulekile, ukuholwa, kanye nokusekelwa okungokomzwelo ezigulini nasemindenini yazo.

Inothi Elibalulekile

Lolu lwazi lungelolwazi olujwayelekile futhi lungenzi izeluleko zezokwelapha. Kubalulekile ukubonisana nodokotela we-ocologist ofanelekayo noma ochwepheshe bezokunakekelwa kwempilo yokuxilongwa komuntu uqobo, ukuhlela ukwelashwa kanye nokunakekelwa okuqhubekayo okuhlobene Ukwelashwa komdlavuza weseli okungewona omncane. Imininingwane eyethulwe lapha ayiyona indawo yeseluleko sokwelashwa esiqeqeshiwe. Njalo funa izeluleko zodokotela wakho noma omunye umhlinzeki wezempilo ofanelekayo nganoma yimiphi imibuzo ongaba nayo mayelana nesimo sezokwelapha.

Ngeminye imininingwane noma ukuhlola izinketho zokwelashwa esikhungweni esihamba phambili sokucwaninga umdlavuza, vakashela I-Shandong Baafa Cancer Research Institute.