Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela

I-pancreatic callt calters trancer hinges ngezinto ezifana nesiteji, indawo, kanye nempilo yonke. Izindlela ezijwayelekile zifaka ukuhlinzwa, imisebe, i-chemotherapy, kanye nokwelashwa okuhlosiwe. Ukuqonda izimbangela, kusuka ekubhekeni kwezakhi zofuzo kuya ezicini zokuphila, ingculazi ekuvinjelweni nasekutholeni kusenesikhathi. Lo mhlahlandlela uhlola lezi zici futhi uqokomisa izibhedlela ezihlonishwayo ezihlolayo Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela. I-Shandong Baafa Cancer Research Institute isendaweni yangaphambili yokucwaninga ngomdlavuza kanye nokwelashwa komdlavuza we-pancreatic Cancerpancreatic ivela lapho amaseli epancreas, isitho esibalulekile sokugaya kanye nokulawulwa kwegazi. Ukutholwa kusenesikhathi kuyinselele ngenxa yezimpawu zayo ezivame ukucaca, okwenza kube lube lube lube lube lube lube lube lube lube lube lube lube lube lube lubalulekile ukuqonda izici zobungozi kanye nezimpawu ezithile zesexwayiso. Ama-pancreas adlala indima ebalulekile ekukhiqizeni ama-enzyme asiza ukugaya kanye nama-hormone aqukethe i-insulin elawula i-adenocarcinoma, esuka kumaseli we-exocrine abhekele ukukhiqiza ama-enzymes aqukethe. Izinhlobo ezijwayelekile ezijwayelekile zifaka ama-neuroendocrine tumors (ama-PNET), aqhamuka kumaseli e-endocrine akhiqiza ama-hormone.Ukwenza yini imbangela ye-pancreatic? Ngenkathi izizathu ezimbalwa zengozi zikhulisa amathuba okuthuthuka Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela. Lokhu kufaka phakathi: Ukubhema: Isici esibi esisengozini, ukukhulisa amathuba omdlavuza we-pancreatic. Ukukhuluphala: Ukukhuluphala ngokweqile noma ukukhuluphala kuphakamisa ubungozi. Isifo sikashukela: Isifo sikashukela esisukuma isikhathi eside singaba nomthelela engcupheni eyandayo. I-pancreatitis engapheli: Ukuvuvukala kwamanyikwe ngokuhamba kwesikhathi. Umlando Womndeni: Umlando womndeni we-pancreatic cancer noma ama-syndromes athile afuywayo afana ne-brca1 / 2 izilonda, i-lynch syndrome, kanye ne-pepuutz-jeggys syndrome. Iminyaka: Ubungozi bukhuphuka ngeminyaka, evame ukutholakala kakhulu kubantu abadala abadala. Ukudla: Ukudla okuphezulu ekudleni okucutshunguliwe kanye nenyama ebomvu kungakhuphula izinketho zokuhlukunyezwa kwengozi ku- Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela Kuya ngezici eziningana, kufaka phakathi isigaba somdlavuza, indawo yaso, kanye nempilo yesiguli. Izindlela ezijwayelekile zifaka phakathi: Ukuhlinzekwa kweSurgerysurgery imvamisa kuyindlela yokwelashwa eyinhloko yomdlavuza we-pancreatic ohlelekile, okusho ukuthi isimila singasuswa ngokuphelele. Uhlobo oluthile lokuhlinzwa luncike endaweni yesimila. Izinqubo ezijwayelekile zifaka: Inqubo YoShrepple (PancreaticodueneEctomy): Ukususwa kwekhanda lamanyikwe, okuyingxenye yamathumbu amancane, i-gallbladder, ne-bile duct. I-PanCreatectomy edakayo: Ukususwa komsila nomzimba wamanyikwe, kuvame ukufaka i-spleen. I-Total PanCreatectomy: Ukususwa kwawo wonke ama-pancreas, kudinga impilo ye-enzyme yempilo yonke kanye ne-insulin elibuyiselwe indawo ye-insulin. Ingasetshenziswa ngaphambi kokuhlinzwa ukuncipha isimila (i-neadjuvant Therapy), ngemuva kokuhlinzwa amaseli okugcina (ukwelashwa okusafuzo), noma ukwelashwa okungekho kwenzeke. Ingasetshenziswa yedwa noma inhlanganisela nezinye zokwelashwa njengokuhlinzwa kanye nokwelashwa kwemisebe. Izidakamizwa ezijwayelekile ze-chemotherapy zomdlavuza we-pancreatic zihlanganisa i-gemcitabine, i-paclitaxel, kanye ne-fluorouracil (5-FU) izidakamizwa zokwelapha ezihlosiwe. Le mishanguzo ivame ukusetshenziselwa iziguli ezinomdlavuza we-pancreatic osezingeni eliphezulu kanye nokuguqulwa okuthile kwezakhi zofuzo. Isibonelo izidakamizwa ziqondise i-EGFR yePakay.Immunotherapyimmunothetherapy kuqinisa amasosha omzimba okulwa nomdlavuza. Yize kungakaze kusetshenziswe kabanzi ngomdlavuza we-pancreatic, izivivinyo eziqhubekayo zemitholampilo zihlola amandla aze, ikakhulukazi amathumbu anezindlela ezithile ze-biomarkers.adwa izindlela zokwelashwa komdlavuza womdlavuza we-shandong Baofa I-Shandong Baafa Cancer Research Institute, sizinikezele ekuphayona kokulashwa kwezindlela ezintsha zokwelashwa Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela. Sinikeza uhla lwezokwelapha ezithuthukile, kufaka phakathi: Ukuhlinzwa okuncane okuhlaselayo: Isebenzisa amasu we-laparoscopic ne-robotic ukunciphisa isikhathi sokutakula futhi uthuthukise imiphumela yeziguli. Ukwelashwa kwemisebe yokunemba: Ukusebenzisa amasu athuthukile afana ne-IMRT ne-SBTT ukuletha imisebe yemisebe ebhekiswe kakhulu ngenkathi kuvinjeze izicubu ezinempilo. I-regimens ye-chemotherapy eyenzelwe wena: Ukulinganisa ama-regimens chemotherapy kususelwa ezifweni zeziguli ngazinye kanye ne-tumoy biology. Izilingo Zomtholampilo: Ukubamba iqhaza ekusikeni kokulingwa kwemitholampilo ukubheka izindlela zokwelapha ezintsha nezithembisayo ze-pancreatic cancer.Coosing Isibhedlela ukuze sikwazi ukwelashwa komdlavuza we-pancreatic Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela kubalulekile. Cabanga ngalezi zinto ezilandelayo: Isipiliyoni: Funa izibhedlela ezinevolumu ephezulu yeziguli zomdlavuza we-pancreatic kanye nodokotela ohlinzayo, oncologists, kanye nabelaphi bemisebe. Iqembu le-Multidisciplinary: Qinisekisa ukuthi isibhedlela sinethimba labanye ochwepheshe abasebenzisana nezinhlelo zokuthola ukwelashwa umuntu ngamunye. Ubuchwepheshe obuthuthukisiwe: Khetha isibhedlela nge-Technologies ye-State-of-the-art. Izilingo Zomtholampilo: Cabanga ngezibhedlela ezinikeza ukufinyelela ezilingweni zokwelashwa zezokwelapha zenoveli. Izinsizakalo Zokusekela: Funa izibhedlela ezihlinzeka ngezinsizakalo eziphelele zokusekelwa, kufaka phakathi ukwelulekwa ngokunempilo, ukuphathwa kobuhlungu kanye nokusekelwa okungokomzwelo.Izibhedlela ezithinta umdlavuza womdlavuza we-pancreatic, lolu hlu alupheleli, izibhedlela eziningana zibonwa ngobuchwepheshe bazo ngaphakathi Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela: I-Shandong Baafa Cancer Research Institute: Eyaziwa ngocwaningo lwayo oluthuthukile kanye nokunakekelwa okugxile kweziguli. I-MD Anderson Cancer Center (USA): Isikhungo Somdlavuza Esihola phambili ngokugxila okuqinile ocwaningweni lomdlavuza we-pancreatic nokwelashwa. Mayo Clinic (USA): Inikeza ukunakekelwa okuphelele kanye nendlela ehlukahlukene ye-pancreatic cancer. Johns Hopkins Hospital (USA): Idume ngobuchwepheshe bayo ekuhlinzweni kwe-pancreatic.Iving nge-pancreatic rancerving enomdlavuza we-pancreatic kungaba inselele, kepha ukusekelwa kuyatholakala. Kubalulekile ukugxila ekugcinweni kwendlela yokuphila enempilo, ukuphatha izimpawu, nokufuna ukusekelwa okungokomzwelo okuvela emndenini, kubangane, noma amasu okusekelwa.Izinhlelo zokusekelayo azikho indlela eqinisekisiwe yokuvimbela umdlavuza we-pancreatic, Ukuyeka ukubhema: Ukubhema kuyisici esikhulu sengozi. Ukugcina isisindo esinempilo: Ukukhuluphala kwandisa ingozi. Ukuphatha isifo sikashukela: Lawula amazinga akho kashukela wegazi uma unesifo sikashukela. Ukudla ukudla okunempilo: Gxila kwizithelo, imifino, kanye nezinhlamvu eziphelele. Ukunciphisa ukusetshenziswa kotshwala: Ukudla ngokweqile kotshwala kungakhulisa ubungozi.Izintela zokusinda komdlavuza we -pancreatic RounceSpancrancree ziyehluka ngokuya ngezinto eziningana, kufaka phakathi isigaba somdlavuza ekuxilongeni, impilo yesiguli ephelele, kanye nokwelashwa okutholakele. Ukutholwa kusenesikhathi nokuphathwa ngolaka kubalulekile ekwenzeni ngcono imiphumela yokusinda.Izinga eli-5 elisindile libhekisela emaphesenti eziguli ezihlala okungenani iminyaka emi-5 ngemuva kokutholakala komdlavuza wazo. Kodwa-ke, kubalulekile ukukhumbula ukuthi amanani okusinda alinganiselwa futhi angahluka ngokuya ngezimo ngazinye. Isigaba seminyaka emi-5 yokusinda kweminyaka engu-5 (Amaseli omdlavuza angama-20% atholakala kuphela ekulweni kwe-pancreatic ducts. Ibizwa nangokuthi i-carcinoma ku-situ. Isiteji Ia ~ 18% Isimila ngamasentimitha ama-2 (cm) noma ngaphansi kokuwela futhi kuphela kumanyikwe. I-Stage Ib ~ 16% Isimila singaphezu kwama-2 cm ngaphesheya futhi kumanyikwe kuphela. Isigaba IIA ~ 9% Umdlavuza usabalale ngaphesheya kwamanyikwe ezicutshini eziseduzane nezitho zangasese kepha hhayi ezifundweni ze-lymph eziseduze. Isiteji Iib ~ 7% Umdlavuza usakazekele kwizindawo eziseduzane ze-lymph futhi kungenzeka nokuthi usatshalaliswe ngaphesheya kwamanyikwe ezicutshini eziseduzane nezitho. Isiteji III ~ 5% Umdlavuza usakazeke emithanjeni emikhulu yegazi eduze kwamanyikwe futhi kungenzeka ukuthi usakazekele ukuya ezindaweni eziseduze zama-lymph. Isigaba IV ~ 3% Umdlavuza usakaze kumasayithi akude, njengesibindi, amaphaphu, noma i-peritoneum. Umthombo: I-American Cancer SocietyUkuqondisa Izimbangela, Umdlavuza we-Pancreatic wezokwelapha ubangela izibhedlela, namasu okuvimbela umdlavuza we-pancreatic kubalulekile. Ukutholwa kusenesikhathi, ukufinyelela kwezinketho zokwelashwa athuthukile, nethimba lezokunakekelwa kwempilo elisekelayo lingathinta kakhulu imiphumela. Xhumana nodokotela wakho ukuthi baxoxe ngezinto zakho zobungozi futhi bathuthukise uhlelo oluqondene nomuntu uqobo lokuvimbela nokutholwa kusenesikhathi.