Ukwelashwa RCC

Ukuqonda nokuphatha i-Renal Cell Carcinoma (RCC) Izinketho zokwelashwa kwe-UpgerTreation ze-Renal Cell Carcinoma (I-RCC) ahlukene futhi ancike ezicini eziningana, kufaka phakathi isigaba somdlavuza, impilo yesiguli, kanye nezimpawu ezithile zesimila. Lo mhlahlandlela ophelele uhlola okuhlukahlukene ukwelapha isondela I-RCC, enikela ngokuqonda ekusebenzeni kwawo kanye nemiphumela emibi engaba khona. Sizokwenza izinketho zokuhlinzwa, izindlela zokwelapha ezihlosiwe, i-immunotherapy, nemisebe, ukuhlinzeka ngokuqonda okucacile kwalesi sifo esiyinkimbinkimbi.

Ukuqonda i-Renal Cell Carcinoma (RCC)

I-Renal Cell Carcinoma (I-RCC) Uhlobo lomdlavuza wezinso ovela ekulweni kwamabhuzu weso. Uhlobo oluvame kakhulu yiseli elicacile I-RCC, kepha amanye ama-subtype akhona, ngalinye linezimpawu zalo ezihlukile kanye nokucatshangelwa kokwelashwa. Ukutholwa kusenesikhathi kuthuthukisa kakhulu amathuba okuphumelela ukwelapha. Izici zobungozi zifaka ukubhema, ukukhuluphala, umfutho wegazi ophakeme, nomlando womndeni womdlavuza wezinso. Izimpawu zingaba ukucasuka noma zingekho ezigabeni zokuqala, kepha zingafaka igazi emchameni, izinhlungu ezithambile, kanye nesisindo esine-palpable esiswini.

Izitebhisi kanye nokuxilongwa kwe-RCC

Ukuzibandakanya okunembile kubalulekile ekunqumeni okufanele ukwelapha hlela I-RCC. Lokhu kufaka amasu wokucabanga afana ne-CT Scans kanye ne-MRI Scans ukubheka ubukhulu besimila nokusakazwa kwayo ezindaweni eziseduze ze-lymph noma ezinye izitho. I-biopsy ingahle idingeke ukuqinisekisa ukuxilongwa futhi inqume uhlobo oluthile lwe I-RCC. Izinhlelo ezihlangene, njengohlelo lwe-TNM, usizo lwe-oncologists luhlukanisa umdlavuza futhi lubikezele ukuqondiswa kwe-prognosis.

Izinketho zokwelashwa ze-RCC

Ukwelapha ingomane I-RCC Ukuhlukahluka okususelwa esiteji nasezicini zomdlavuza. Okuyisisekelo ukwelapha Izinketho zifaka:

Ukususwa Kwezinso (Nephrectomy)

Okwenzelwe okwenziwe I-RCC, nephrectomy - ukususwa kokuhlinzwa kwezinso ezithintekile - kuvame ukuba yinhloko ukwelapha. Lokhu kungenziwa ngokuhlinzwa okuvulekile, i-laparoscopy, noma ukuhlinzwa okusizwa ngamarobhothi. Ukukhethwa kwendlela yokuhlinza kuncike ezintweni ezifana nosayizi nendawo yendawo yesimila kanye nempilo yesiguli. Ingxenye ye-Nephrectomy eyingxenye, ehilela ukususa kuphela isimila nengxenye encane yezinso, kungaba yinketho kwezinye izimo ukuze ilondoloze umsebenzi wezinso.

Ukwelashwa okuhlosiwe

Izindlela zokwelapha ezihlosiwe zinemithi ebhekise ngqo amaseli omdlavuza, ukunciphisa ukulimala kwamaseli anempilo. Izidakamizwa eziningana ezibhekiswe ezibhekiswe eziqondisiwe ziye zafakazela ukuthi ngempumelelo ekwelashweni okuthuthukile I-RCC. Le mishanguzo isebenza ngokuvimbela amaprotheni athile noma izindlela ezibandakanyeka ekukhuleni kweseli yomdlavuza kanye nokusinda. Izibonelo zifaka iSunitinib, i-sorafenib, i-pazopanib, ne-axitinib. Imiphumela emibi evamile ingafaka ukukhathala, umfutho wegazi ophakeme, nesifo sangemuva kwe-hand-foot.

I-ImmunoSatherapy

I-ImmunoSatherapy ihlanganisa amasosha omzimba uqobo ukuze alwe nomdlavuza. Ukuvikelwa komzimba Huritont, njengeNivolumab ne-Ipilamab, baguqule ukwelapha Okuthuthukile I-RCC. Le mishanguzo isebenza ngokuvimba amaprotheni avimbela amasosha omzimba ekuhlaseleni amaseli omdlavuza. Ngenkathi isebenza kakhulu kwezinye iziguli, i-immunotherapy nayo ingaba nemiphumela emibi ebalulekile, kufaka phakathi ukusabela kwe-autoimmune.

Ukwelashwa kwemisebe

Ukwelashwa kwemisebe kusebenzisa imisebe yamandla aphezulu ukubulala umdlavuza amaseli. Ngokuvamile akusona okuyisisekelo ukwelapha ingomane I-RCC Kepha kungenzeka ukuthi isetshenziswe ezimweni ezithile, njengokudambisa izinhlungu ezibangelwa isifo semetastatic noma ukwelapha ukuphindaphindeka kwasendaweni ngemuva kokuhlinzwa.

Okunye ukwelashwa

-Nye nje ukwelapha Izinhlobo, ezinjenge-chemotherapy kanye nokwelashwa kwemvelo, zingasetshenziswa ezimweni ezithile ngokuya ngecala lesiguli kanye nomdlavuza. Indlela yethimba lama-multidiculinary, elibandakanya ama-norologists, ama-oncologists, kanye nabanye ochwepheshe bezokunakekelwa kwempilo, kuqinisekisa iziguli zithola ukunakekelwa okuphelele nokwenziwe ngokwezifiso.

Ukukhetha uhlelo lokulashwa olufanele

Ukukhetha okufanele kakhulu ukwelapha ingomane I-RCC kudinga ukucatshangelwa ngokucophelela kwezinto ezimbalwa. Lesi sinqumo kufanele senziwe ngokubonisana ne-Oncologist efanelekayo, sinaka isigaba nohlobo lwe I-RCC, impilo yesiguli ephelele, kanye nezingozi ezingaba khona nezinzuzo zalowo nalowo ukwelapha Inketho. Le khasi I-Shandong Baafa Cancer Research Institute ihlinzeka ngezindawo zombuso kanye nochwepheshe abanolwazi lokuxilongwa futhi ukwelapha womdlavuza ohlukahlukene, kufaka phakathi I-RCC.

Ukugcina

Le khasi ukwelapha I-Landscape for I-RCC Uhlala uvela njalo, ngezindlela ezintsha zokwelapha nokuthuthuka okunikezela ngemiphumela ethuthukisiwe yeziguli. Ukutholwa kusenesikhathi nokusheshisa ukwelapha zibalulekile ukuthola imiphumela efanele. Lo mhlahlandlela uhlinzeka ngesibukezo sabahlukahlukene ukwelapha Izinketho ziyatholakala, kepha kubalulekile ukuze uthintane nochwepheshe wezokunakekelwa kwempilo ukuze uthole ukuholwa komuntu uqobo kanye ne-a ukwelapha Hlela.