Izinketho zokwelashwa zesigaba 3 Umdlavuza wama-Inglies On-Small Lungephu

Isiteji 3 Umdlavuza we-Cell Lung Leng (NSCLC) uletha izinselelo ezihlukile, edinga indlela ehlukahlukene ekwelashweni. Lo mhlahlandlela ophelele uhlola izinketho ezahlukahlukene zokwelashwa, uchaza ukusebenza kwazo, imiphumela emibi engaba khona, kanye nokufaneleka ngokuya ngezinto ezifundeni. Ukuqonda lezi zinketho kubalulekile ngokwenza izinqumo ezinolwazi kanye ne-Oncologist yakho.

Ukuqonda isigaba 3 NSCLC

Isigaba 3 NSCLC sihlukaniswe esigabeni se-IIIA ne-IIB, okukhombisa ubukhulu bomdlavuza asakazekelayo. Isiteji I-IIII sibandakanya umdlavuza osabalale ezinhlakeni eziseduze ze-lymph, ngenkathi isigaba se-IIIB sihlanganisa ukuhilela ukuhilela okubanzi kwe-lymph node kanye / noma ukusakazekela ezakhiweni eziseduze. Izitayela ezinembile eziku-imaging (ama-CT Scans, ama-pet scans) kanye nama-biopsies kubalulekile ekunqumeni okuhle kakhulu Ukwelashwa Isigaba 3 Ukuphathwa komdlavuza we-cell okungumuntu omncane Hlela.

Izindlela zokwelashwa ze-Stage 3 NSCLC

Indawo kadokotela

Ukuhlinzwa kungaba yindlela yokukhetha okukhethiwe kwesigaba se-IIII With ukuzibandakanya okulinganiselwe kwe-nodal kanye nempilo enhle. Lokhu kungafaka i-lobectomy (ukususwa kweLung Lobe) noma i-pneumonectomy (ukususwa kwalo lonke amaphaphu). Ukuvuselelwa kokuhlinzwa kuvame ukulandela ukwelashwa okunama-admivant (chemotherapy noma imisebe) ukunciphisa ingozi yokuphindaphinda. Isinqumo sokuqhubeka nokuhlinzwa sincike ezicini eziningana, kufaka phakathi indawo nosayizi wesimila, impilo yesiguli ephelele, kanye nobungako be-Lymph Node. I-Shandong Baafa Cancer Research Institute Inikeza ubuchwepheshe obuphelele bokuhlinzwa bomdlavuza wamaphaphu.

Chemotherapy

I-Chemotherapy, isebenzisa izidakamizwa ezinamandla ukubulala umdlavuza amaseli, kuvamile Ukwelashwa Isigaba 3 Ukuphathwa komdlavuza we-cell okungumuntu omncane Nge-STATE IIIA ne-IIIB NSCLC. Ama-Regimens ahlukahluka ngokuya ngezinto ngazinye, futhi angafaka izidakamizwa ezisuselwa kwiplatinamu (i-cisplatin noma i-carboplatin) ehlanganiswe nabanye abasebenzi abanjenge-pemetred noma i-doncetaxel. I-Chemotherapy ingahanjiswa ngaphambi kokuhlinzwa (i-neadjuvant) ukuncipha isimila, ngemuva kokuhlinzwa (adgevant) ukuqeda amaseli omdlavuza asele, noma njengokuphathwa okuyisisekelo. Imiphumela emibi iyajwayelekile futhi ingafaka i-nausea, ukukhathala, kanye nokulahleka kwezinwele; Kodwa-ke, lokhu kuvame ukungalawulwa ngokunakekelwa okusekelayo.

Ukwelashwa kwemisebe

Ukwelashwa kwemisebe kusebenzisa imisebe ephakeme yamandla ukushabalalisa amaseli womdlavuza. Ingasetshenziswa yedwa noma inhlanganisela nge-chemotherapy. Ukwelapha imisebe kungahle kusetshenziswe ngaphambi kokuhlinzwa (i-neAVJuvant) ukuncipha isimila, ngemuva kokuhlinzwa (i-adjuvant) ukuqondisa noma yimaphi amaseli omdlavuza asele, noma ukwelashwa okuyisisekelo, ikakhulukazi iziguli ezingezona ezihlotshisiwe. Ukwelashwa kwemisebe yemisebe yeStereotactic (SBTT) kuyindlela eqondile yemisebe enikezela ngemithamo ephezulu yemisebe ibe yisimila ngenkathi usindisa izicubu ezinempilo. Uhlobo oluthile kanye nomthamo wokwelashwa kwemisebe kuncike esimweni somuntu ngamunye.

Ukwelashwa okuhlosiwe

Ukwelashwa okuhlosiwe kusebenzisa izidakamizwa eziqondise ngqo amaseli omdlavuza ngokususelwa ekuguqukeni kwabo kofuzo. Izinguquko ezithile zofuzo (njenge-EGFR, i-ALK, i-ROS1 Dections) zivame kakhulu ku-NSCLC futhi zingabikezela ukuphendula kwezindlela eziqondile ezihlosiwe. Uma ukuguqulwa okunjalo kukhonjwa, ukwelashwa okuhlosiwe kungaba yitshe le-Cornterstone Ukwelashwa Isigaba 3 Ukuphathwa komdlavuza we-cell okungumuntu omncane, ngokuqondene nemiphumela ethuthukisiwe kanye nemiphumela emibi embalwa ngokuqhathaniswa nendabuko ye-chemotherapy. Udokotela wakho we-oncologist uzoqhuba ukuhlolwa kofuzo ukuthola ukuthi ngabe ukwelashwa okuqondisiwe kufanelekile yini kuwe.

I-ImmunoSatherapy

I-ImmunoSatherapy ihlanganisa amandla amasosha omzimba uqobo ukuze alwe nomdlavuza. I-Imc Vipoint inhibitors, njenge-nivolumab noma i-pembrolikumab, isetshenziselwa ukuvimba amaprotheni avimbela amasosha omzimba ekuhlaseleni amaseli omdlavuza. I-ImmunoSatherapy ivame ukusetshenziswa ngokuhlanganiswa ne-chemotherapy futhi ingaba inketho yeziguli ezinamaphrofayili athile genetic noma labo abangazange baphendule kahle kwezinye izindlela zokwelapha. Imiphumela emibi kungenzeka futhi iyahluka ngokuya ngemithi ethile.

Ukukhetha uhlelo lokulashwa olufanele

Okulungile Ukwelashwa Isigaba 3 Ukuphathwa komdlavuza we-cell okungumuntu omncane Isu lincike ezicini eziningana, kufaka phakathi isigaba somdlavuza, impilo yesiguli ephelele, kanye nokuba khona kwezinguquko ezithile zofuzo. Ithimba elijwayelekile le-Oncologists, odokotela abahlinzayo, kanye nabelaphi bemisebe bazosebenza ngokubambisana ukuthuthukisa uhlelo lokwelashwa oluqondene nomuntu uqobo. Ukuxhumana okuvulekile nomhlinzeki wakho wezokunakekelwa kwezempilo kubalulekile ekuqondeni izinketho zakho nokwenza izinqumo ezinolwazi ngokunakekelwa kwakho.

Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi akufanele lubhekwe njengeluleke lwezokwelapha. Hlala uthintana nomhlinzeki wakho wezokunakekelwa kwempilo ukuze uthole ukutholakala nokwelashwa kwanoma yisiphi isimo sezokwelapha.

Ukuzikhulula: Lolu lwazi luhloselwe ulwazi olujwayelekile kanye nezinhloso zolwazi kuphela, futhi alwenzi izeluleko zezokwelapha. Kubalulekile ukuthintana nochwepheshe wezempilo ofanelekayo nganoma yiziphi izinkathazo zezempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo yakho noma yokwelashwa. Imininingwane enikeziwe lapha akufanele ibhekwe njengendawo yeseluleko esifanele sezokwelapha, ukuxilongwa, noma ukwelashwa.