Izinketho zokwelashwa zeStage 4 Renal Cell Carcinoma

Isigaba 4 Renal Cell Carcinoma (RCC) ingukuxilongwa okuyinselele, kepha intuthuko ekwelashweni inikeza ithemba lemiphumela ethuthukisiwe. Lo mhlahlandlela ophelele uhlola izindlela ezahlukahlukene zokwelashwa, ugxile emikhubeni engcono kakhulu kanye nokucatshangelwa kweziguli ezibhekene nalesi sigaba esithuthukile somdlavuza wezinso. Ukuqonda izinketho ezitholakalayo kanye nezinzuzo zabo ezingaba khona kanye nobungozi kubalulekile ekuthatheni izinqumo okunolwazi eceleni kwe-Oncologist yakho. Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi alwenzi izeluleko zezokwelapha.

Ukuqonda isigaba 4 Renal cell carcinoma

Ukuxilongwa kanye nokuqina

Ukuxilongwa okunembile kwe Isigaba 4 Renal cell carcinoma kubaluleke kakhulu. Lokhu kufaka phakathi ukuhlolwa kokucabanga okufana nezikena ze-CT kanye ne-MRI Scans, eceleni kwe-biopsy ukuqinisekisa ubukhona nohlobo lwamaseli omdlavuza. Isitayela sinquma ubukhulu bokusakazeka komdlavuza, okuthinta ukukhetha ukwelashwa. Isigaba 4 sibonisa ukuthi umdlavuza wehleliwe, okusho ukuthi usakaze ezithweni ezikude, imvamisa amaphaphu, amathambo, noma isibindi. Isazi se-Oncologist sizodingida izitebhisi zakho ezithile kanye ne-pronyothothos ngokusekelwe kwicala lakho ngalinye.

Izici ze-Prognostic

Kunezici eziningana zithonya ukugcwaliseka kwe Isigaba 4 Renal cell carcinoma, kufaka phakathi indawo nenombolo yama-metastases, impilo yesiguli ephelele, kanye nohlobo lwe-RCC. Lezi zinto zisiza ukuqondisa izinqumo zokwelashwa futhi zibikezele imiphumela engenzeka. Udokotela wakho uzobheka lokhu lapho ethuthukisa uhlelo lokwelashwa oluqondene nomuntu uqobo. Ukuxhumana okuvulekile nethimba lakho lezempilo kubalulekile kulo lonke le nqubo.

Ukwelashwa Kwendlela Yesigaba 4 Renal Cell Carcinoma

Ukwelashwa okuhlosiwe

Izindlela zokwelapha ezihlosiwe zenzelwe ukuhlasela amaseli athize umdlavuza ngenkathi kunciphisa ukulimala kumaseli anempilo. Ama-ejenti ambalwa ahlosiwe afakazele ngempumelelo ekwelapheni i-metastatic RCC, kufaka phakathi ama-tyrosine kinase inhibitors (TKIS) njenge-sunitinib, iPazoPanib, ne-axitinib. Le mithi ingahle iphathwe ngomlomo futhi ibonise ukuthuthuka okukhulu ekusindeni kwamahhala kweziguli nge Isigaba 4 Renal cell carcinoma. Ukukhethwa kokwelashwa okuhlosiwe kuzoncika ezicini ngazinye futhi kungashintshwa ngokuhamba kwesikhathi ngokuya ngemiphumela emibi. Funda kabanzi mayelana nezinketho zokwelapha ezihlosiwe ezivela kwiNational Cancer Institute.

I-ImmunoSatherapy

I-ImmunoSatherapy ihlanganisa amasosha omzimba uqobo ukuze alwe namaseli womdlavuza. Ukuhlola ama-inhibitors, njenge-nivolumab ne-ipilamab, kusetshenziselwa ukwelapha i-RCC ethuthukile. Le mishanguzo isebenza ngokuvimba amaprotheni avimbela amasosha omzimba ekuhlaseleni amaseli omdlavuza, avumele izivikelo zomzimba ukuthi zihlose ngempumelelo futhi ziqede isimila. Le ndlela ikhombisile impumelelo ebalulekile ekuthuthukiseni amanani okusinda kwezinye iziguli Isigaba 4 Renal cell carcinoma. Imiphumela emibi kungenzeka futhi kuzoxoxwa ngayo nodokotela wakho ngaphambi kokuqala kokwelashwa.

Therapy Cytokine

I-Interleukin-2 (IL-2) iyi-cytokine evuselela amasosha omzimba. Ngenkathi kuvame ukusetshenziswa ekwelashweni komugqa wokuqala we Isigaba 4 Renal cell carcinoma Manje kuqhathaniswa nezinketho ezintsha nezikhohlakele kanye ne-immunotherapy, kungabhekwa ezimweni ezithile futhi kuhlala kuyingxenye ebalulekile yendawo yokwelashwa. Udokotela wakho uzokuhlola ngokucophelela ukufaneleka kwawo kwesimo sakho ngasinye.

Okunye ukwelashwa

Kwezinye izimo, ezinye izindlela zokwelapha zingasetshenziswa ngokuhlanganiswa noma ngaphezu kwezindlela zokwelapha ezishiwo ngenhla. Lokhu kungafaka ukuhlinzwa (ukususa ama-metastases uma kungenzeka), ukwelashwa kwemisebe (ukuphatha izinhlungu noma ukulawula ukusakazeka kwasendaweni), noma ukunakekelwa okusekelwayo (ukuphatha izimpawu futhi kuthuthukiswe ikhwalithi yempilo). I-Shandong Bandoong BacceCancer Research Institute (https://www.baofahospital.com/) Isikhungo esiphambili socwaningo lomdlavuza nokwelashwa, sinikela kakhulu ekuthuthukisweni kulo mkhakha.

Ukwenza Izinqumo Ezinolwazi

Ukukhetha uhlelo lokulashwa olufanele

Uhlelo lokwelashwa olufanele lwe- Isigaba 4 Renal cell carcinoma kucatshangelwe kakhulu futhi kuya ngezinto eziningana. Lokhu kufaka phakathi impilo yesiguli ephelele, ubukhulu bomdlavuza ukusakazeka, ukwelashwa kwangaphambilini, kanye nokuthandwa ngumuntu. Kubalulekile ukuba nezingxoxo ezivulekile nezithembekile ne-Oncologist yakho ngezinzuzo ezingaba khona kanye nobungozi benketho yokwelashwa ngakunye ngaphambi kokwenza isinqumo. Le ndlela yokubambisana iqinisekisa ukuthi uthola ukunakekelwa okufanele kakhulu nokwenzelwe umuntu.

Izilingo Zomtholampilo

Ukubamba iqhaza kwecala lomtholampilo kunganikeza ukufinyelela ekwelashweni okusha futhi kufake isandla ekuthuthukiseni ucwaningo lomdlavuza. Ukuvivinywa kwemitholampilo kubhekwe ngokucophelela izifundo ezihlola ukuphepha nokusebenza kahle kokwelashwa okusha. I-Oncologist yakho ingaxoxa ukuthi ukubamba iqhaza esivivinyweni esifanele sokwelashwa kungaba inketho efanelekile kuwe. Inhlangano yeNational Cancer Institure igcina i-database ephelele yezilingo zomtholampilo.

Ukunakekelwa Okusekelayo

Ukuphila ne Isigaba 4 Renal cell carcinoma Imvamisa iveza izinselelo, futhi ukunakekelwa kokusekela kudlala indima ebalulekile ekugcineni ikhwalithi yempilo. Lokhu kufaka izinsizakalo ezahlukahlukene ukubhekana nezimpawu zomzimba, inhlala-kahle engokomzwelo, nezidingo ezingokoqobo. Ukunakekelwa kokusekelwa kungafaka ukuphathwa kwezinhlungu, ukwelulekwa kokudla okunempilo, ukwelashwa ngokomzimba, amaqembu okusekelwa ngokomzwelo, kanye nokuthola izinsiza zosizo lwezezimali. Iqembu lakho lezempilo lizoxhumanisa lezi zinsizakalo ukuze liqinisekise ukuthi uthola ukwesekwa okuphelele kulo lonke uhambo lwakho.

Ukuzikhulula: Lolu lwazi lwenzelwe izinjongo zokufundisa kuphela futhi lungenzi izeluleko zezokwelapha. Hlala uthintana nomhlinzeki wakho wezokunakekelwa kwezempilo nganoma yiziphi izinkathazo zezempilo noma ngaphambi kokwenza noma yiziphi izinqumo ezihlobene nempilo yakho noma yokwelashwa.

Imithombo:

I-National Cancer Institute